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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1972 2
1973 3
1976 4
1980 1
1991 1
1992 4
1993 53
1994 115
1995 211
1996 220
1997 184
1998 265
1999 329
2000 411
2001 504
2002 637
2003 559
2004 479
2005 482
2006 573
2007 541
2008 506
2009 480
2010 489
2011 387
2012 362
2013 281
2014 289
2015 262
2016 276
2017 269
2018 234
2019 76
2020 0
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8,784 results
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Page 1
Coupling of exocytosis and endocytosis at the presynaptic active zone.
Maritzen T and Haucke V. Neurosci Res 2018 - Review. PMID 29221907
The presynaptic AZ comprises an assembly of large multidomain proteins that link the machinery for vesicle fusion to sites of voltage-dependent Ca(2+) entry. ...Here we discuss the evidence supporting such exo-endocytic coupling as well as possible modes and mechanisms that may underlie coupling of exocytosis and endocytosis at and around AZs in presynaptic nerve terminals. ...
The presynaptic AZ comprises an assembly of large multidomain proteins that link the machinery for vesicle fusion to sites of voltage …
Mitochondria at the neuronal presynapse in health and disease
Devine MJ and Kittler JT. Nat Rev Neurosci 2018 - Review. PMID 29348666
Presynaptically, this communication requires energy and generates large fluctuations in calcium concentrations. Mitochondria are optimized for supplying energy and buffering calcium, and they are actively recruited to presynapses. ...Here, we discuss the importance of presynaptic mitochondria in maintaining neuronal homeostasis and how dysfunctional presynaptic mitochondria might contribute to the development of disease....
Presynaptically, this communication requires energy and generates large fluctuations in calcium concentrations. Mitochondria are opti
Presynaptic Calcium Channels.
Mochida S. Int J Mol Sci 2019 - Review. PMID 31064106 Free PMC article.
Presynaptic Ca(2+) entry occurs through voltage-gated Ca(2+) (Ca(V)) channels which are activated by membrane depolarization. ...The presynaptic Ca(V)2 channel gene family (comprising Ca(V)2.1, Ca(V)2.2, and Ca(V)2.3 isoforms) encode the pore-forming α1 subunit. ...
Presynaptic Ca(2+) entry occurs through voltage-gated Ca(2+) (Ca(V)) channels which are activated by membrane depolarization. ...The
Strength and precision of neurotransmission at mammalian presynaptic terminals.
Takahashi T. Proc Jpn Acad Ser B Phys Biol Sci 2015 - Review. PMID 26194855 Free PMC article.
Classically, the basic concept of chemical synaptic transmission was established at the frog neuromuscular junction, and direct intracellular recordings from presynaptic terminals at the squid giant presynaptic terminal have further clarified principles of neurotransmitter release. ...The mechanisms by which presynaptic terminals acquire strong, precise neurotransmission during postnatal development are also discussed....
Classically, the basic concept of chemical synaptic transmission was established at the frog neuromuscular junction, and direct intracellula …
Excitement about inhibitory presynaptic terminals.
Vandael DH, et al. Neuron 2015. PMID 25789750 Free article.
In this issue of Neuron, using subcellular patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba (2015) show that at Purkinje cell-deep cerebellar nuclei neuron synapses, changes in presynaptic action potential waveform substantially contribute to synaptic depression....
In this issue of Neuron, using subcellular patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba ( …
Presynaptic origins of distinct modes of neurotransmitter release.
Chanaday NL and Kavalali ET. Curr Opin Neurobiol 2018 - Review. PMID 29597140 Free PMC article.
Presynaptic nerve terminals release neurotransmitter synchronously, asynchronously or spontaneously. During synchronous neurotransmission release is precisely coupled to action potentials, in contrast, asynchronous release events show only loose temporal coupling to presynaptic activity whereas spontaneous neurotransmission occurs independent of presynaptic activity. ...Recent studies have described several presynaptic molecular pathways controlling synaptic vesicle pool segregation and recycling, which in turn may dictate distinct modes of neurotransmitter release. ...
Presynaptic nerve terminals release neurotransmitter synchronously, asynchronously or spontaneously. During synchronous neurot
The Eloquent Silent Synapse
Vincent-Lamarre P, et al. Trends Neurosci 2018 - Review. PMID 30143180
Autophagy in the presynaptic compartment.
Lüningschrör P and Sendtner M. Curr Opin Neurobiol 2018 - Review. PMID 29549710
Regulated release of neurotransmitter depends on the orchestrated function of a large number of proteins in the presynaptic compartment. ...The corresponding presynaptic autophagy system thus appears also important for synaptic maintenance and plasticity. Exciting new studies provide evidence how the autophagy machinery recognizes and degrades synaptic components and lay the ground to understand how autophagy in the presynaptic compartment contributes to modulation and maintenance of synaptic function....
Regulated release of neurotransmitter depends on the orchestrated function of a large number of proteins in the presynaptic compartme …
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