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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 10
1988 18
1989 22
1990 32
1991 40
1992 45
1993 31
1994 53
1995 45
1996 55
1997 47
1998 87
1999 116
2000 115
2001 121
2002 129
2003 166
2004 137
2005 159
2006 173
2007 201
2008 219
2009 213
2010 200
2011 252
2012 253
2013 265
2014 252
2015 261
2016 280
2017 309
2018 356
2019 201
2020 5
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4,448 results
Results by year
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Page 1
Prodrugs - Recent approvals and a glimpse of the pipeline.
Rautio J, Kärkkäinen J, Sloan KB. Rautio J, et al. Eur J Pharm Sci. 2017 Nov 15;109:146-161. doi: 10.1016/j.ejps.2017.08.002. Epub 2017 Aug 4. Eur J Pharm Sci. 2017. PMID: 28782609 Review.
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses.
Siegel D, Hui HC, Doerffler E, Clarke MO, Chun K, Zhang L, Neville S, Carra E, Lew W, Ross B, Wang Q, Wolfe L, Jordan R, Soloveva V, Knox J, Perry J, Perron M, Stray KM, Barauskas O, Feng JY, Xu Y, Lee G, Rheingold AL, Ray AS, Bannister R, Strickley R, Swaminathan S, Lee WA, Bavari S, Cihlar T, Lo MK, Warren TK, Mackman RL. Siegel D, et al. J Med Chem. 2017 Mar 9;60(5):1648-1661. doi: 10.1021/acs.jmedchem.6b01594. Epub 2017 Feb 14. J Med Chem. 2017. PMID: 28124907
Self-assembling prodrugs.
Cheetham AG, Chakroun RW, Ma W, Cui H. Cheetham AG, et al. Chem Soc Rev. 2017 Oct 30;46(21):6638-6663. doi: 10.1039/c7cs00521k. Chem Soc Rev. 2017. PMID: 29019492 Free PMC article. Review.
Special focus: metals in medicine.
Spencer J, Walden B. Spencer J, et al. Future Med Chem. 2018 Mar 1;10(6):607-609. doi: 10.4155/fmc-2018-9999. Future Med Chem. 2018. PMID: 29508658 Free article. No abstract available.
Lipid-Drug Conjugate for Enhancing Drug Delivery.
Irby D, Du C, Li F. Irby D, et al. Mol Pharm. 2017 May 1;14(5):1325-1338. doi: 10.1021/acs.molpharmaceut.6b01027. Epub 2017 Jan 24. Mol Pharm. 2017. PMID: 28080053 Free PMC article. Review.
Prodrugs of triterpenoids and their derivatives.
Zhou M, Zhang RH, Wang M, Xu GB, Liao SG. Zhou M, et al. Eur J Med Chem. 2017 May 5;131:222-236. doi: 10.1016/j.ejmech.2017.03.005. Epub 2017 Mar 6. Eur J Med Chem. 2017. PMID: 28329729 Review.
Amino Acids in the Development of Prodrugs.
Vale N, Ferreira A, Matos J, Fresco P, Gouveia MJ. Vale N, et al. Molecules. 2018 Sep 11;23(9):2318. doi: 10.3390/molecules23092318. Molecules. 2018. PMID: 30208629 Free PMC article. Review.
The Taxonomy of Covalent Inhibitors.
Tuley A, Fast W. Tuley A, et al. Biochemistry. 2018 Jun 19;57(24):3326-3337. doi: 10.1021/acs.biochem.8b00315. Epub 2018 Apr 30. Biochemistry. 2018. PMID: 29689165 Free PMC article. Review.
Strategies toward Organic Carbon Monoxide Prodrugs.
Ji X, Wang B. Ji X, et al. Acc Chem Res. 2018 Jun 19;51(6):1377-1385. doi: 10.1021/acs.accounts.8b00019. Epub 2018 May 15. Acc Chem Res. 2018. PMID: 29762011
Prodrug Strategies for Paclitaxel.
Meng Z, Lv Q, Lu J, Yao H, Lv X, Jiang F, Lu A, Zhang G. Meng Z, et al. Int J Mol Sci. 2016 May 23;17(5):796. doi: 10.3390/ijms17050796. Int J Mol Sci. 2016. PMID: 27223283 Free PMC article. Review.
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