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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 4
1987 2
1988 1
1989 4
1990 10
1991 28
1992 38
1993 41
1994 51
1995 45
1996 37
1997 47
1998 63
1999 89
2000 74
2001 116
2002 151
2003 280
2004 390
2005 431
2006 412
2007 466
2008 420
2009 411
2010 442
2011 449
2012 452
2013 460
2014 403
2015 422
2016 472
2017 450
2018 389
2019 178
2020 1
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7,027 results
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Page 1
Protein Engineering Approaches in the Post-Genomic Era.
Singh RK, et al. Curr Protein Pept Sci 2018 - Review. PMID 27855603
Protein engineering aims to design new proteins or modify the sequence of a protein to create proteins with new or desirable functions. ...Rational design is an effective method of protein engineering when the threedimensional structure and mechanism of the protein is well known. ...
Protein engineering aims to design new proteins or modify the sequence of a protein to create proteins with new or desi
Protein Engineering: Past, Present, and Future.
Lutz S and Iamurri SM. Methods Mol Biol 2018 - Review. PMID 29086300
This trend has to a significant degree been fueled by advances in scientists' and engineers' ability to customize native enzymes by protein engineering. ...Herein, we use history to guide a brief overview of the major strategies for protein engineering-past, present, and future....
This trend has to a significant degree been fueled by advances in scientists' and engineers' ability to customize native enzymes
Protein engineering and its applications in food industry.
Kapoor S, et al. Crit Rev Food Sci Nutr 2017 - Review. PMID 26065315
Protein produced properly from genetic engineering process means a protein that is able to fold correctly and to do particular function(s) efficiently even after being subjected to engineering practices. Protein is modified through its gene or chemically. However, modification of protein through gene is easier. There is no specific limitation of Protein Engineering tools; any technique that can lead to change the protein constituent of amino acid and result in the modification of protein structure/function is in the frame of Protein Engineering. ...
Protein produced properly from genetic engineering process means a protein that is able to fold correctly and to do par
Current Trends in Protein Engineering: Updates and Progress.
Sinha R and Shukla P. Curr Protein Pept Sci 2019 - Review. PMID 30451109
Given its tremendous relevance, protein engineering has emerged as significant biotechnological intervention in this area. Strategic utilization of protein engineering methods and approaches has enabled better enzymatic properties, better stability, increased catalytic activity and most importantly, interesting and wide range applicability of proteins. ...Protein engineering has also evolved to become a powerful tool contributing significantly to the developments in both synthetic biology and metabolic engineering. ...
Given its tremendous relevance, protein engineering has emerged as significant biotechnological intervention in this area. Str …
Unified rational protein engineering with sequence-based deep representation learning.
Alley EC, et al. Nat Methods 2019. PMID 31636460
Rational protein engineering requires a holistic understanding of protein function. Here, we apply deep learning to unlabeled amino-acid sequences to distill the fundamental features of a protein into a statistical representation that is semantically rich and structurally, evolutionarily and biophysically grounded. ...UniRep further enables two orders of magnitude efficiency improvement in a protein engineering task. UniRep is a versatile summary of fundamental protein features that can be applied across protein engineering informatics....
Rational protein engineering requires a holistic understanding of protein function. Here, we apply deep learning to unl …
Protein engineering approaches to chemical biotechnology.
Chen Z and Zeng AP. Curr Opin Biotechnol 2016 - Review. PMID 27525565
Although widely used in single-enzyme catalysis process, protein engineering is only being increasingly explored in recent years to achieve more complex in vitro and in vivo biocatalytic processes. This review focuses on major contributions of protein engineering to chemical biotechnology in the field of multi-enzymatic cascade catalysis and metabolic engineering. ...
Although widely used in single-enzyme catalysis process, protein engineering is only being increasingly explored in rec …
Protein engineering: the potential of remote mutations.
Wilding M, et al. Biochem Soc Trans 2019 - Review. PMID 30902926
This minireview will discuss the current state of the art in protein engineering, with a particular focus on engineering regions that are remote from active- or ligand-binding sites. As the use of protein technologies expands, exploiting the potential improvements made possible through modifying remote regions will become vital if we are to realise the full potential of protein engineering and design....
This minireview will discuss the current state of the art in protein engineering, with a particular focus on engineering
Membrane protein engineering to the rescue.
Rawlings AE. Biochem Soc Trans 2018 - Review. PMID 30381335 Free article.
For many years, the only way of working with membrane proteins was to optimise the environment to suit the protein, through the use of different detergents, solubilising additives, and other adaptations. However, with innovative protein engineering methodologies, the membrane proteins themselves are now being adapted to suit the environment. ...
For many years, the only way of working with membrane proteins was to optimise the environment to suit the protein, through th …
Just (protein) engineering?
Hollfelder F and Lutz S. Curr Opin Struct Biol 2013. PMID 23886559
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