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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2003 1
2009 1
2010 2
2011 111
2012 335
2013 350
2014 337
2015 329
2016 333
2017 359
2018 291
2019 175
2020 17
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2,268 results
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Page 1
Targeted protein degradation: expanding the toolbox.
Schapira M, Calabrese MF, Bullock AN, Crews CM. Schapira M, et al. Nat Rev Drug Discov. 2019 Dec;18(12):949-963. doi: 10.1038/s41573-019-0047-y. Epub 2019 Oct 30. Nat Rev Drug Discov. 2019. PMID: 31666732
Targeted protein degradation by PROTACs.
Neklesa TK, Winkler JD, Crews CM. Neklesa TK, et al. Pharmacol Ther. 2017 Jun;174:138-144. doi: 10.1016/j.pharmthera.2017.02.027. Epub 2017 Feb 14. Pharmacol Ther. 2017. PMID: 28223226 Review.
Development of targeted protein degradation therapeutics.
Chamberlain PP, Hamann LG. Chamberlain PP, et al. Nat Chem Biol. 2019 Oct;15(10):937-944. doi: 10.1038/s41589-019-0362-y. Epub 2019 Sep 16. Nat Chem Biol. 2019. PMID: 31527835 Review.
Ubiquitin System.
Nakamura N. Nakamura N. Int J Mol Sci. 2018 Apr 4;19(4):1080. doi: 10.3390/ijms19041080. Int J Mol Sci. 2018. PMID: 29617326 Free PMC article.
PROTACs- a game-changing technology.
Konstantinidou M, Li J, Zhang B, Wang Z, Shaabani S, Ter Brake F, Essa K, Dömling A. Konstantinidou M, et al. Expert Opin Drug Discov. 2019 Dec;14(12):1255-1268. doi: 10.1080/17460441.2019.1659242. Epub 2019 Sep 20. Expert Opin Drug Discov. 2019. PMID: 31538491 Free PMC article. Review.
Targeted Protein Degradation: from Chemical Biology to Drug Discovery.
Cromm PM, Crews CM. Cromm PM, et al. Cell Chem Biol. 2017 Sep 21;24(9):1181-1190. doi: 10.1016/j.chembiol.2017.05.024. Epub 2017 Jun 22. Cell Chem Biol. 2017. PMID: 28648379 Free PMC article. Review.
Protein degradation for drug discovery.
Ciulli A, Farnaby W. Ciulli A, et al. Drug Discov Today Technol. 2019 Apr;31:1-3. doi: 10.1016/j.ddtec.2019.04.002. Drug Discov Today Technol. 2019. PMID: 31200853 No abstract available.
SIRT5 regulation of ammonia-induced autophagy and mitophagy.
Polletta L, Vernucci E, Carnevale I, Arcangeli T, Rotili D, Palmerio S, Steegborn C, Nowak T, Schutkowski M, Pellegrini L, Sansone L, Villanova L, Runci A, Pucci B, Morgante E, Fini M, Mai A, Russo MA, Tafani M. Polletta L, et al. Autophagy. 2015;11(2):253-70. doi: 10.1080/15548627.2015.1009778. Autophagy. 2015. PMID: 25700560 Free PMC article.
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H. Takahashi D, et al. Mol Cell. 2019 Dec 5;76(5):797-810.e10. doi: 10.1016/j.molcel.2019.09.009. Epub 2019 Oct 9. Mol Cell. 2019. PMID: 31606272
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