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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 2
1991 46
1992 164
1993 244
1994 307
1995 380
1996 429
1997 483
1998 408
1999 384
2000 427
2001 453
2002 399
2003 459
2004 469
2005 487
2006 455
2007 498
2008 544
2009 565
2010 537
2011 475
2012 495
2013 516
2014 560
2015 508
2016 451
2017 447
2018 401
2019 148
2020 4
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10,994 results
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Page 1
c-Fos and related immediate early gene products as markers of activity in neuroendocrine systems.
Hoffman GE, et al. Front Neuroendocrinol 1993 - Review. PMID 8349003
Expression of c-Fos, or other immediate early gene products, by individual neurons can be used as a marker of cell activation, making staining of these proteins an extremely useful technique for functional anatomical mapping of neuroendocrine systems. ...In our studies, we focus primarily on expression of one immediate early gene product, the c-Fos protein. We also include some experiments using expression of other members of the Fos family and Jun proteins as markers for neuronal activation. ...
Expression of c-Fos, or other immediate early gene products, by individual neurons can be used as a marker of cell activation, …
From c-Fos to MMP-9: In control of synaptic plasticity to produce healthy and diseased mind, a personal view.
Kaczmarek L. Postepy Biochem 2018. PMID 30656892 Free article.
c-Fos is a component of AP-1 transcription factor. Three lines of evidence support pivotal role of c-Fos in learning and memory: (i) learning experience markedly enhances its expression; (ii) blocking od c-Fos impairs, while optogenetic activation of c-Fos expressing neurons supports learning and memory; (iii) c-Fos/AP-1 gene targets in activated neurons, encoding tissue inhibitor of metalloproteinases-1 (TIMP-1) and matrix metalloproteinase 9 (MMP- 9) play a major role in synaptic plasticity that underlies learning and memory. ...
c-Fos is a component of AP-1 transcription factor. Three lines of evidence support pivotal role of c-Fos in lear
A Neuronal Hub Binding Sleep Initiation and Body Cooling in Response to a Warm External Stimulus
Harding EC, et al. Curr Biol 2018. PMID 30017485 Free PMC article.
To address whether external warmth induces sleep through defined circuitry, we used c-Fos-dependent activity tagging, which captures populations of activated cells and allows them to be reactivated to test their physiological role. ...
To address whether external warmth induces sleep through defined circuitry, we used c-Fos-dependent activity tagging, which ca …
∆FosB: a transcriptional regulator of stress and antidepressant responses
Nestler EJ. Eur J Pharmacol 2015 - Review. PMID 25446562 Free PMC article.
ΔFosB is a member of the Fos family of transcription factors. While other family members are induced rapidly but transiently in response to a host of acute stimuli, ΔFosB is unique in that it accumulates in response to repeated stimulation due to its unusual protein stability. ...
ΔFosB is a member of the Fos family of transcription factors. While other family members are induced rapidly but transiently in respo …
c-Fos immunoreactivity in the hypothalamus and reward system of young rats after social novelty exposure.
Gómez-Gómez YM, et al. Neuroreport 2019. PMID 30896675
After stimuli exposure, brains were fixed and cut in coronal sections for c-Fos immunohistochemistry. The number of c-Fos-immunoreactive (c-Fos-ir) neurons in the paraventricular nucleus and supraoptic nucleus, the main producers of oxytocin and vasopressin, was compared, as well as in the nucleus accumbens and ventral pallidum, the main areas involved in reinforced behavior. A significantly higher number of c-Fos-ir neurons were found in animals exposed to social novelty in all areas, except in the supraoptic nucleus. ...
After stimuli exposure, brains were fixed and cut in coronal sections for c-Fos immunohistochemistry. The number of c- …
c-Fos induction by gut hormones and extracellular ATP in osteoblastic-like cell lines.
Pacheco-Pantoja EL, et al. Purinergic Signal 2016. PMID 27439698 Free PMC article.
It is widely accepted that the c-Fos gene has a role in proliferation and differentiation of bone cells. ATP-induced c-Fos activation is relevant to bone homeostasis, because nucleotides that are present in the environment of bone cells can contribute to autocrine/paracrine signalling. Gut hormones have previously been shown to have an effect on bone metabolism. In this study, we used the osteoblastic Saos-2 cell line transfected with a c-Fos-driven reporter stimulated with five gut hormones: glucose inhibitory peptide (GIP), glucagon-like peptide-1 (GLP-1), glucagon-like peptide-2 (GLP-2), ghrelin and obestatin, in the presence or absence of ATP. ...
It is widely accepted that the c-Fos gene has a role in proliferation and differentiation of bone cells. ATP-induced c- …
The mechanism of acute fasting-induced antidepressant-like effects in mice
Cui R, et al. J Cell Mol Med 2018. PMID 28782175 Free PMC article.
Therefore, in this study the antidepressant-like effects of acute fasting on c-Fos expression and BDNF levels were investigated. ...Fasting-induced c-Fos expression was further enhanced by DOI in prefrontal cortex, and these enhancements were inhibited by ketanserin. ...
Therefore, in this study the antidepressant-like effects of acute fasting on c-Fos expression and BDNF levels were investigate …
Effects of electrical stimulation of the rat vestibular labyrinth on c-Fos expression in the hippocampus.
Hitier M, et al. Neurosci Lett 2018. PMID 29694841
We found that vestibular stimulation increased the number of animals expressing c-Fos in the dorsal HPC compared to sham control rats (P ≤ 0.02), but not in the ventral HPC. c-Fos was also expressed in an increased number of animals in the dorsal dentate gyrus (DG) compared to sham control rats (P ≤ 0.0001), and to a lesser extent in the ventral DG (P ≤ 0.006). The results of this study show that activation of the vestibular system results in a differential increase in the expression of c-Fos across different regions of the HPC....
We found that vestibular stimulation increased the number of animals expressing c-Fos in the dorsal HPC compared to sham contr …
Experience-dependent c-Fos expression in the primary chemosensory cortices of the rat.
Bamji-Stocke S, et al. Brain Res 2018. PMID 30244018 Free PMC article.
To determine how previous experience impacts the primary chemosensory cortices, we compared the expression of the immediate early gene, c-Fos, between rats presented with a taste, an odor, or an odor-taste mixture for the first-time with rats that had many days of prior experience. Compared to rats with prior experience, we found that first-time sampling of all three chemosensory stimuli led to significantly greater c-Fos expression in gustatory cortex. ...
To determine how previous experience impacts the primary chemosensory cortices, we compared the expression of the immediate early gene, c
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