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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 19
1993 31
1994 58
1995 118
1996 133
1997 144
1998 163
1999 204
2000 254
2001 266
2002 297
2003 342
2004 379
2005 467
2006 421
2007 398
2008 507
2009 654
2010 677
2011 637
2012 709
2013 726
2014 790
2015 778
2016 858
2017 811
2018 767
2019 366
2020 19
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10,939 results
Results by year
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Page 1
Proton pump inhibitors: use and misuse in the clinical setting.
Savarino V, et al. Expert Rev Clin Pharmacol 2018 - Review. PMID 30295105
The introduction of proton pump inhibitors (PPIs) into clinical practice has greatly improved our therapeutic approach to acid-related diseases for their efficacy and safety. ...
The introduction of proton pump inhibitors (PPIs) into clinical practice has greatly improved our therapeutic approach …
The appropriate use of proton-pump inhibitors.
Savarino V, et al. Minerva Med 2018 - Review. PMID 29856192
The introduction of proton-pump inhibitors (PPIs) into clinical practice since about thirty years has greatly improved our therapeutic approach to acid-related diseases for their well recognized efficacy and safety. ...
The introduction of proton-pump inhibitors (PPIs) into clinical practice since about thirty years has greatly improved …
Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline.
Farrell B, et al. Can Fam Physician 2017. PMID 28500192 Free PMC article.
OBJECTIVE: To develop an evidence-based guideline to help clinicians make decisions about when and how to safely taper or stop proton pump inhibitors (PPIs); to focus on the highest level of evidence available and seek input from primary care professionals in the guideline development, review, and endorsement processes. ...
OBJECTIVE: To develop an evidence-based guideline to help clinicians make decisions about when and how to safely taper or stop proton
Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine.
El Rouby N, et al. Expert Opin Drug Metab Toxicol 2018 - Review. PMID 29620484 Free PMC article.
Proton Pump inhibitors (PPIs) are commonly used for a variety of acid related disorders. Despite the overall effectiveness and safety profile of PPIs, some patients do not respond adequately or develop treatment related adverse events. ...
Proton Pump inhibitors (PPIs) are commonly used for a variety of acid related disorders. Despite the overall effectiven
Proton pump inhibitors for functional dyspepsia.
Pinto-Sanchez MI, et al. Cochrane Database Syst Rev 2017 - Review. PMID 29161458 Free PMC article.
Acid suppressive therapy, including proton pump inhibitors (PPIs), has been proposed as a therapeutic option in FD, but its efficacy remains controversial. ...OBJECTIVES: To determine the efficacy of proton pump inhibitors in the improvement of global symptoms of dyspepsia and quality of life compared to placebo, H2 receptor antagonists or prokinetics, in people with functional dyspepsia. ...
Acid suppressive therapy, including proton pump inhibitors (PPIs), has been proposed as a therapeutic option in FD, but …
Proton Pump Inhibitors: Risks and Rewards and Emerging Consequences to the Gut Microbiome.
Singh A, et al. Nutr Clin Pract 2018 - Review. PMID 30071147
In recent years, proton pump inhibitors (PPIs) have been criticized for their various adverse interactions and side effects, creating a dilemma among practitioners regarding their use. ...
In recent years, proton pump inhibitors (PPIs) have been criticized for their various adverse interactions and side eff …
Proton Pump Inhibitors: Risk for Myopathy?
Colmenares EW and Pappas AL. Ann Pharmacother 2017 - Review. PMID 27539734
OBJECTIVE: The purpose of this article is to describe the relationship between proton pump inhibitors (PPIs) and symptoms of myopathy based on case reports. DATA SOURCES: A literature search was conducted in PubMed (1946 to June 2016) using MeSH terms proton pump inhibitors, omeprazole, esomeprazole, lansoprazole, dexlansoprazole, rabeprazole, pantoprazole, and muscular diseases. ...
OBJECTIVE: The purpose of this article is to describe the relationship between proton pump inhibitors (PPIs) and sympto …
Proton pump inhibitors affect the gut microbiome.
Imhann F, et al. Gut 2016. PMID 26657899 Free PMC article.
BACKGROUND AND AIMS: Proton pump inhibitors (PPIs) are among the top 10 most widely used drugs in the world. PPI use has been associated with an increased risk of enteric infections, most notably Clostridium difficile. ...
BACKGROUND AND AIMS: Proton pump inhibitors (PPIs) are among the top 10 most widely used drugs in the world. PPI use ha …
Proton Pump Inhibitors: What the Internist Needs to Know.
Spechler SJ. Med Clin North Am 2019 - Review. PMID 30466666
This report reviews the physiology of gastric acid suppression by proton pump inhibitors (PPIs) and anti-inflammatory effects of PPIs that are independent of their acid-suppressive effects. ...
This report reviews the physiology of gastric acid suppression by proton pump inhibitors (PPIs) and anti-inflammatory e …
Interchangeable Use of Proton Pump Inhibitors Based on Relative Potency.
Graham DY and Tansel A. Clin Gastroenterol Hepatol 2018. PMID 28964908 Free PMC article.
Although proton pump inhibitors (PPIs) are widely used, their relative potency and ideal dosing regimens remain unclear. We analyzed data from randomized clinical trials that performed pH testing in patients receiving solid-dose PPI formulations (omeprazole, esomeprazole, lansoprazole, pantoprazole, rabeprazole) for a minimum of 5 days. ...
Although proton pump inhibitors (PPIs) are widely used, their relative potency and ideal dosing regimens remain unclear …
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