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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 11
2008 56
2009 87
2010 121
2011 109
2012 127
2013 121
2014 124
2015 118
2016 130
2017 138
2018 139
2019 62
2020 2
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1,181 results
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Proton pump inhibitors: Risks of long-term use.
Eusebi LH, et al. J Gastroenterol Hepatol 2017 - Review. PMID 28092694
Proton pump inhibitors are among the most commonly prescribed classes of drugs, and their use is increasing, in particular for long-term treatment, often being over-prescribed and used for inappropriate conditions. ...The most recent literature regarding these adverse effects and their association with long-term proton pump inhibitor treatment is reviewed, and the mechanisms through which these possible complications might develop are discussed....
Proton pump inhibitors are among the most commonly prescribed classes of drugs, and their use is increasing, in particular for
Proton-pump inhibitors: understanding the complications and risks.
Malfertheiner P, et al. Nat Rev Gastroenterol Hepatol 2017 - Review. PMID 28930292
Proton-pump inhibitors (PPIs) are the most effective therapy for the full spectrum of gastric-acid-related diseases. However, in the past decade, a steadily increasing list of complications following long-term use of PPIs has been reported. ...
Proton-pump inhibitors (PPIs) are the most effective therapy for the full spectrum of gastric-acid-related diseases. However,
Adverse effects of proton pump inhibitors: fact or fake news?
Schubert ML. Curr Opin Gastroenterol 2018 - Review. PMID 30102612
PURPOSE OF REVIEW: The present review summarizes the past year's literature, both clinical and basic science, regarding potential adverse effects of proton pump inhibitors. ...SUMMARY: Most of the recent highly publicized serious adverse effects ascribed to proton pump inhibitors are not based on demonstrable evidence. ...
PURPOSE OF REVIEW: The present review summarizes the past year's literature, both clinical and basic science, regarding potential adverse ef …
Proton pump inhibitors and osteoporosis.
Andersen BN, et al. Curr Opin Rheumatol 2016 - Review. PMID 27224743
PURPOSE OF REVIEW: The purpose of the review is to provide an update on recent advances in the evidence based on proton pump inhibitors (PPI) as a possible cause of osteoporosis and osteoporotic fractures. ...
PURPOSE OF REVIEW: The purpose of the review is to provide an update on recent advances in the evidence based on proton pump i …
Proton Pump Inhibitors: What the Internist Needs to Know.
Spechler SJ. Med Clin North Am 2019 - Review. PMID 30466666
This report reviews the physiology of gastric acid suppression by proton pump inhibitors (PPIs) and anti-inflammatory effects of PPIs that are independent of their acid-suppressive effects. ...
This report reviews the physiology of gastric acid suppression by proton pump inhibitors (PPIs) and anti-inflammatory effects …
Side Effects of Long-Term Proton Pump Inhibitor Use: A Review.
Haastrup PF, et al. Basic Clin Pharmacol Toxicol 2018 - Review. PMID 29658189 Free article.
Proton pump inhibitors (PPIs) are widely used, and concerns about overuse have been raised. Therefore, side effects are important to be aware of and several suggested side effects of long-term use have been studied. ...
Proton pump inhibitors (PPIs) are widely used, and concerns about overuse have been raised. Therefore, side effects are import
The relationship between proton pump inhibitors and renal disease.
Morschel CF, et al. J Bras Nefrol 2018 - Review. PMID 30010692 Free PMC article.
Proton pump inhibitors (PPIs) bind to enzyme H+/K+-ATPase and inhibit its activity in the stomach, thus decreasing the secretion of gastric acid. ...
Proton pump inhibitors (PPIs) bind to enzyme H+/K+-ATPase and inhibit its activity in the stomach, thus decreasing the secreti
Adverse Events of Proton Pump Inhibitors: Potential Mechanisms.
Corsonello A, et al. Curr Drug Metab 2018 - Review. PMID 29219052
OBJECTIVE: We aimed at summarizing current evidence about mechanisms for potentially harmful effects of Proton Pump Inhibitors (PPIs). ...
OBJECTIVE: We aimed at summarizing current evidence about mechanisms for potentially harmful effects of Proton Pump Inhibitors …
Proton Pump Inhibitors: Risks and Rewards and Emerging Consequences to the Gut Microbiome.
Singh A, et al. Nutr Clin Pract 2018 - Review. PMID 30071147
In recent years, proton pump inhibitors (PPIs) have been criticized for their various adverse interactions and side effects, creating a dilemma among practitioners regarding their use. ...
In recent years, proton pump inhibitors (PPIs) have been criticized for their various adverse interactions and side effects, c …
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