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Page 1
Brazilian experts' consensus on the treatment of infantile epileptic spasm syndrome in infants.
Sampaio LPB, Henriques-Souza AMM, Silveira MRMD, Seguti L, Santos MLSF, Montenegro MA, Antoniuk S, Manreza MLG. Sampaio LPB, et al. Arq Neuropsiquiatr. 2023 Sep;81(9):844-856. doi: 10.1055/s-0043-1772835. Epub 2023 Oct 4. Arq Neuropsiquiatr. 2023. PMID: 37793406 Free PMC article.
BACKGROUND: Infantile epileptic spasms syndrome (IESS) is a rare but severe condition affecting children early and is usually secondary to an identifiable brain disorder. It is related to psychomotor deterioration in childhood and epilepsy in adult life. Treatment i …
BACKGROUND: Infantile epileptic spasms syndrome (IESS) is a rare but severe condition affecting children early and is usually secondary to a …
Evaluation of the cognitive, psychomotor and pharmacokinetic profiles of rupatadine, hydroxyzine and cetirizine, in combination with alcohol, in healthy volunteers.
Barbanoj MJ, García-Gea C, Antonijoan R, Izquierdo I, Donado E, Pérez I, Solans A, Jané F. Barbanoj MJ, et al. Hum Psychopharmacol. 2006 Jan;21(1):13-26. doi: 10.1002/hup.741. Hum Psychopharmacol. 2006. PMID: 16389668 Clinical Trial.
METHODS: Eighteen healthy young volunteers of both sexes participated in a phase I, randomised, crossover, double-blind, placebo-controlled study. At 2-week intervals they received six treatments: (a) placebo (PLA), (b) ALC alone and ALC in combination with: (c) hydroxyzin …
METHODS: Eighteen healthy young volunteers of both sexes participated in a phase I, randomised, crossover, double-blind, placebo-cont …
Psychomotor deterioration during exposure to heat.
Epstein Y, Keren G, Moisseiev J, Gasko O, Yachin S. Epstein Y, et al. Aviat Space Environ Med. 1980 Jun;51(6):607-10. Aviat Space Environ Med. 1980. PMID: 7417123
The effect of different heat loads on vigilance and complex cognitive tasks involved in a mission of different intensities were examined. Nine healthy volunteers were randomly exposed for 2 h to three climatic conditions: comfort (21 degrees C ET), moderate heat load (30 d …
The effect of different heat loads on vigilance and complex cognitive tasks involved in a mission of different intensities were examined. Ni …
Vigabatrin-associated brain abnormalities on MRI and other neurological symptoms in patients with West syndrome.
Reyes Valenzuela G, Crespo A, Princich J, Fassulo L, Semprino M, Gallo A, Rugilo C, Pociecha J, Calvo A, Caraballo RH. Reyes Valenzuela G, et al. Epilepsy Behav. 2022 Apr;129:108606. doi: 10.1016/j.yebeh.2022.108606. Epub 2022 Feb 15. Epilepsy Behav. 2022. PMID: 35180571
In the majority, these adverse events were asymptomatic; however, some of the patients developed movement disorders and acute encephalopathy. METHODS: This is a retrospective analysis of our epilepsy clinical and EEG database of 288 patients with WS seen between 2014 and 2 …
In the majority, these adverse events were asymptomatic; however, some of the patients developed movement disorders and acute encephalopathy …
Hypsarrhythmia paroxysm index: A tool for early prediction of infantile spasms.
Altunel A, Sever A, Altunel EÖ. Altunel A, et al. Epilepsy Res. 2015 Mar;111:54-60. doi: 10.1016/j.eplepsyres.2015.01.005. Epub 2015 Jan 25. Epilepsy Res. 2015. PMID: 25769373
Recurrence of infantile spasms (ISs) is common subsequent to treatment with adrenocorticotropic hormone (ACTH) for West syndrome, and prolonged hypsarrhythmia results in psychomotor deterioration. The evolution to hypsarrhythmia involves conversion of prehypsarrhyth …
Recurrence of infantile spasms (ISs) is common subsequent to treatment with adrenocorticotropic hormone (ACTH) for West syndrome, and prolon …
Developmental outcome in five children with Hurler syndrome after stem cell transplantation: a pilot study.
Lücke T, Das AM, Hartmann H, Sykora KW, Donnerstag F, Schmid-Ott G, Grigull L. Lücke T, et al. Dev Med Child Neurol. 2007 Sep;49(9):693-6. doi: 10.1111/j.1469-8749.2007.00693.x. Dev Med Child Neurol. 2007. PMID: 17718826 Free article.
Hematopoietic stem cell transplantation (SCT) is the only treatment known to prevent psychomotor deterioration. However, the classical transplantation protocols resulted in a high incidence of graft failure and regimen-related toxicity. ...
Hematopoietic stem cell transplantation (SCT) is the only treatment known to prevent psychomotor deterioration. However, the c …
Lack of effect of terfenadine on the pharmacokinetics of the CYP3A4 substrate buspirone.
Lamberg TS, Kivistö KT, Neuvonen PJ. Lamberg TS, et al. Pharmacol Toxicol. 1999 Apr;84(4):165-9. doi: 10.1111/j.1600-0773.1999.tb00894.x. Pharmacol Toxicol. 1999. PMID: 10227067 Clinical Trial.
The effects of terfenadine, a non-sedating antihistamine on the pharmacokinetics and pharmacodynamics of buspirone, a CYP3A4 substrate, were investigated in a randomised, placebo-controlled, two-phase cross-over study. Ten healthy volunteers took either 120 mg terfenadine …
The effects of terfenadine, a non-sedating antihistamine on the pharmacokinetics and pharmacodynamics of buspirone, a CYP3A4 substrate, were …
Early childhood hepatocerebral degeneration misdiagnosed as valproate hepatotoxicity.
Bicknese AR, May W, Hickey WF, Dodson WE. Bicknese AR, et al. Ann Neurol. 1992 Dec;32(6):767-75. doi: 10.1002/ana.410320610. Ann Neurol. 1992. PMID: 1471867
Two of these children each had 1 sibling who was not exposed to VPA, but who developed the same clinical picture including liver failure. At the time of autopsy, all 6 children had similar neuropathological findings with focal areas of spongiosis and neuronal loss, diffuse …
Two of these children each had 1 sibling who was not exposed to VPA, but who developed the same clinical picture including liver fail …
Utility of high doses of melatonin as adjunctive anticonvulsant therapy in a child with severe myoclonic epilepsy: two years' experience.
Molina-Carballo A, Muñoz-Hoyos A, Reiter RJ, Sánchez-Forte M, Moreno-Madrid F, Rufo-Campos M, Molina-Font JA, Acuña-Castroviejo D. Molina-Carballo A, et al. J Pineal Res. 1997 Sep;23(2):97-105. doi: 10.1111/j.1600-079x.1997.tb00341.x. J Pineal Res. 1997. PMID: 9392448
The child was initially treated with various anticonvulsants. Severe neurological and psychomotor deterioration combined with increased seizure activity showed a lack of response to the treatment. ...Melatonin has proven to be useful as adjunctive therapy in the …
The child was initially treated with various anticonvulsants. Severe neurological and psychomotor deterioration combined with …
Clinical and EEG video-polygraphic features of epileptic spasms in a child with dihydropteridine reductase deficiency. Efficiency of hydrocortisone.
Mikaeloff Y, Plouin P, Dhondt JL, Ponsot G, Dulac O. Mikaeloff Y, et al. Epileptic Disord. 2000 Dec;2(4):213-7. Epileptic Disord. 2000. PMID: 11174152 Free article.
West syndrome is an epileptic encephalopathy which includes psychomotor deterioration. In rare cases, it is due to an inherited, progressive metabolic disease. ...
West syndrome is an epileptic encephalopathy which includes psychomotor deterioration. In rare cases, it is due to an inherite …
13 results