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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 1
1955 2
1957 2
1958 1
1959 1
1965 4
1966 6
1967 20
1968 8
1969 17
1970 18
1971 22
1972 26
1973 21
1974 27
1975 30
1976 21
1977 27
1978 11
1979 24
1980 31
1981 36
1982 25
1983 30
1984 48
1985 46
1986 62
1987 61
1988 61
1989 95
1990 81
1991 103
1992 93
1993 121
1994 122
1995 143
1996 155
1997 148
1998 157
1999 106
2000 118
2001 110
2002 103
2003 93
2004 109
2005 129
2006 137
2007 133
2008 155
2009 121
2010 147
2011 144
2012 155
2013 136
2014 127
2015 119
2016 116
2017 146
2018 130
2019 52
2020 0
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4,195 results
Results by year
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Page 1
Effects of cigarette smoke on pulmonary endothelial cells.
Lu Q, et al. Am J Physiol Lung Cell Mol Physiol 2018 - Review. PMID 29351435 Free PMC article.
Growing evidence supports the injurious effect of cigarette smoke on pulmonary endothelial cells and the roles of endothelial cell injury in development of acute respiratory distress syndrome (ARDS), emphysema, and pulmonary hypertension. ...The discussion is focused on effects of cigarette smoke-induced endothelial injury in the development of ARDS, emphysema, and vascular remodeling in chronic obstructive pulmonary disease....
Growing evidence supports the injurious effect of cigarette smoke on pulmonary endothelial cells and the roles of endothelial cell in …
The differential effects of systemic vasoconstrictors on human pulmonary artery tension.
Hussain A, et al. Eur J Cardiothorac Surg 2017. PMID 28164217
The aim of this study was to use human pulmonary artery to characterize the pharmacological effects of clinically used vasopressors on the human pulmonary vasculature. ...These effects may need to be taken into account in the clinical setting because they might result in the development of pulmonary hypertension....
The aim of this study was to use human pulmonary artery to characterize the pharmacological effects of clinically used …
The effects of dexmedetomidine on pulmonary artery pressure in experiment.
Unal Y, et al. Bratisl Lek Listy 2014. PMID 25174057
AIM: The primary purpose of this study is to assess the effects of dexmedetomidine (DEX) infusion on pulmonary artery pressures (PAP), heart rate (HR), and mean arterial pressure (MAP) in pigs. The secondary purpose is to evaluate whether DEX infusion via the pulmonary artery has any beneficial effect over the peripheral IV route. ...
AIM: The primary purpose of this study is to assess the effects of dexmedetomidine (DEX) infusion on pulmonary artery p …
<Editors' Choice> Pulmonary Hypertension: Diagnosis, Management, and Treatment.
Kondo T, et al. Nagoya J Med Sci 2019 - Review. PMID 30962652 Free PMC article.
Pulmonary hypertension (PH) is a hemodynamic state that is characterized by a resting mean pulmonary artery pressure ≧ 25 mmHg. ...Previously regarded as untreatable, the treatment of PAH has dramatically advanced since the introduction of the drug epoprostenol in 1999, with three-year survival rates improving from 30%-40% to over 85%. ...
Pulmonary hypertension (PH) is a hemodynamic state that is characterized by a resting mean pulmonary artery pressure ≧
Modern treatment to reduce pulmonary arterial pressure in pulmonary arterial hypertension.
Akagi S, et al. J Cardiol 2018 - Review. PMID 29898864 Free article.
Treatment goals in pulmonary arterial hypertension (PAH) include improved quality of life and exercise capacity as well as improved life prognosis. ...PAH is often a comorbidity with other diseases including congenital heart defect, connective tissue diseases, and pulmonary arterial aneurysm. ...
Treatment goals in pulmonary arterial hypertension (PAH) include improved quality of life and exercise capacity as well as improved l …
Effects of propofol and thiopental in isolated rat aorta and pulmonary artery.
Park WK, et al. Anesthesiology 1992. PMID 1443750
The effects of propofol were compared with those of thiopental on isolated vascular ring preparations from rat thoracic aorta and pulmonary artery. ...Propofol also caused marked vasodilation in pulmonary arteries. In contrast, thiopental had no vasodilating effect in aortic or pulmonary artery preparations. ...
The effects of propofol were compared with those of thiopental on isolated vascular ring preparations from rat thoracic aorta and …
Pulmonary Arterial Hypertension: Combination Therapy in Practice.
Burks M, et al. Am J Cardiovasc Drugs 2018 - Review. PMID 29511993 Free PMC article.
Combination therapy is now regarded as the standard of care in pulmonary arterial hypertension (PAH) and is becoming widely used in clinical practice. ...In initial combination therapy regimens in particular, this may lead to additive side effects and reduced tolerability compared with monotherapy. ...
Combination therapy is now regarded as the standard of care in pulmonary arterial hypertension (PAH) and is becoming widely used in c …
Effects of a localized high-flow anastomosis between the aorta and left lower lobe pulmonary artery on great vessel flow and pulmonary arterial reactivity in the contralateral lung.
Somberg L, et al. J Thorac Cardiovasc Surg 2011. PMID 21075384 Free PMC article.
OBJECTIVES: We sought to assess the effects of a localized anastomosis between the aorta and left lower lobe pulmonary artery on flows through central vessels and on the vascular reactivity of small pulmonary arteries distal or contralateral to the shunt. ...CONCLUSIONS: Our studies are the first to identify enhanced reactivity of pulmonary arteries in a lung contralateral to a localized high-output shunt between an aorta and pulmonary artery. ...
OBJECTIVES: We sought to assess the effects of a localized anastomosis between the aorta and left lower lobe pulmonary arte
Carfilzomib reverses pulmonary arterial hypertension.
Wang X, et al. Cardiovasc Res 2016. PMID 26952044 Free PMC article.
Agents that can reduce the pulmonary vascular thickness thus have therapeutic potential. The present study investigated the efficacy of carfilzomib (CFZ), a proteasome inhibitor and a cancer chemotherapeutic drug, on reversing PAH. ...In human pulmonary artery smooth muscle cells, knocking down mediators of autophagy attenuated CFZ-induced cell death. The cell death role of autophagy was promoted by the participation of tumour protein p53-inducible nuclear protein 1. ...
Agents that can reduce the pulmonary vascular thickness thus have therapeutic potential. The present study investigated the efficacy …
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