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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1950 1
1951 14
1952 36
1953 73
1954 89
1955 66
1956 69
1957 85
1958 62
1959 38
1960 3
1963 1
1964 6
1965 121
1966 253
1967 407
1968 499
1969 660
1970 695
1971 762
1972 853
1973 872
1974 863
1975 738
1976 641
1977 680
1978 685
1979 782
1980 749
1981 835
1982 903
1983 979
1984 1107
1985 1209
1986 1164
1987 1369
1988 1265
1989 1328
1990 1299
1991 1341
1992 1437
1993 1516
1994 1534
1995 1436
1996 1548
1997 1490
1998 1532
1999 1554
2000 1466
2001 1559
2002 1616
2003 1659
2004 1722
2005 1769
2006 1950
2007 2208
2008 2260
2009 2435
2010 2616
2011 2734
2012 2892
2013 2921
2014 2939
2015 2919
2016 2959
2017 2814
2018 2534
2019 1143
2020 15
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75,942 results
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Page 1
Xanthines and Phosphodiesterase Inhibitors
Spina D and Page CP. Handb Exp Pharmacol 2017 - Review. PMID 27844172
However, in most treatment guidelines, xanthines have now been consigned to third-line therapy because of their narrow therapeutic window and propensity for drug-drug interactions. ...Although theophylline has a narrow therapeutic window, other xanthines are in clinical use that are claimed to have a better tolerability such as doxofylline and bamifylline. ...
However, in most treatment guidelines, xanthines have now been consigned to third-line therapy because of their narrow therapeutic wi …
Commentary
Stocco G. Clin Chem 2013. PMID 23813429
Commentary
Reid AE. Clin Chem 2013. PMID 23813428
A position statement on the management of patients with pityriasis rosea
Chuh A, et al. J Eur Acad Dermatol Venereol 2016 - Review. PMID 27406919
Our statement comprises the follows: (i) The diagnosis of PR should be ascertained; (ii) The patients should be assessed for rash severity and impacts on quality of life; (iii) PR is a self-limiting disease, and most patients do not necessitate any treatment; (iv) For patients necessitating active treatment, oral acyclovir as 400 mg three times daily for 7 days can be considered; (v) Attention should be given to adverse effects and contraindications of acyclovir; (vi) When PR occurs in early pregnancy, oral antiviral therapy could be considered after consulting experienced clinicians; (vii) Inadequate information exists in the use of acyclovir to treatment PR in children and breastfeeding women; and (viii) Treating PR is an off-label use of acyclovir, and this has to be discussed with experienced colleagues and the patients....
Our statement comprises the follows: (i) The diagnosis of PR should be ascertained; (ii) The patients should be assessed for rash severity a …
Comparative Efficacy and Safety of Caffeine and Aminophylline for Apnea of Prematurity in Preterm (≤34 weeks) Neonates: A Randomized Controlled Trial
Shivakumar M, et al. Indian Pediatr 2017 - Clinical Trial. PMID 28474588 Free article.
Association of efficacy with therapeutic drug levels was also evaluated. RESULTS: Infants on aminophylline experienced less apnea spells in 4-7 days of therapy (P=0.03). ...
Association of efficacy with therapeutic drug levels was also evaluated. RESULTS: Infants on aminophylline experienced less apnea spe …
Switching from tenofovir disoproxil fumarate to tenofovir alafenamide in antiretroviral regimens for virologically suppressed adults with HIV-1 infection: a randomised, active-controlled, multicentre, open-label, phase 3, non-inferiority study
Mills A, et al. Lancet Infect Dis 2016 - Clinical Trial. PMID 26538525
With use of a third-party computer-generated sequence, patients were randomly assigned (2:1) to receive a once-a-day single-tablet containing elvitegravir 150 mg, cobicistat 150 mg, emtricitabine 200 mg, and tenofovir alafenamide 10 mg (tenofovir alafenamide group) or to carry on taking one of four previous tenofovir disoproxil fumarate-containing regimens (tenofovir disoproxil fumarate group) for 96 weeks. ...
With use of a third-party computer-generated sequence, patients were randomly assigned (2:1) to receive a once-a-day single-tablet co …
Allopurinol
Rundles W. N Engl J Med 1969. PMID 5775639
Azathioprine
[No authors listed] Br Med J 1966. PMID 5957425 Free PMC article.
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