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1968 1
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1975 2
1977 2
1978 1
1979 1
1981 1
1982 2
1983 1
1984 1
1985 5
1986 4
1987 3
1988 6
1989 7
1991 5
1992 4
1993 1
1994 2
1996 3
1997 4
1998 2
1999 2
2000 2
2001 4
2002 3
2003 4
2004 5
2005 6
2006 4
2007 6
2008 6
2009 3
2010 1
2011 3
2012 2
2013 2
2014 2
2015 7
2016 3
2017 3
2018 1
2019 1
2020 0
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Page 1
The corticospinal tract: Evolution, development, and human disorders.
Welniarz Q, et al. Dev Neurobiol 2017 - Review. PMID 27706924 Free article.
A comparison of CST anatomy and development across mammalian species first highlights important similarities. In particular, most CST axons cross the anatomical midline at the junction between the brainstem and spinal cord, forming the pyramidal decussation. ...These latter disorders result in altered midline crossing at the pyramidal decussation or in the spinal cord, but spare the rest of the CST. ...
A comparison of CST anatomy and development across mammalian species first highlights important similarities. In particular, most CST …
Development of the Corticospinal and Callosal Tracts from Extremely Premature Birth up to 2 Years of Age.
Braga RM, et al. PLoS One 2015. PMID 25955638 Free PMC article.
White matter tracts mature asymmetrically during development, and this development can be studied using diffusion magnetic resonance imaging. ...We found evidence for asymmetric development across the fiber bundles studied, with the corticospinal tracts showing earlier maturation (as measured by fractional anisotropy) but slower volumetric growth compared to the callosal fibers. ...
White matter tracts mature asymmetrically during development, and this development can be studied using diffusion magne …
Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo.
Arlotta P, et al. Neuron 2005. PMID 15664173 Free article.
In order to elucidate molecular mechanisms underlying the specification and development of corticospinal motor neurons (CSMN), we purified CSMN at distinct stages of development in vivo and compared their gene expression to two other pure populations of cortical projection neurons: callosal projection neurons and corticotectal projection neurons. We found genes that are potentially instructive for CSMN development, as well as genes that are excluded from CSMN and are restricted to other populations of neurons, even within the same cortical layer. ...
In order to elucidate molecular mechanisms underlying the specification and development of corticospinal motor neurons (CSMN), we pur …
[Development and maturation of the pyramidal tract].
Kubis N and Catala M. Neurochirurgie 2003 - Review. PMID 12746689 French.
The growth of these axons is highly regulated and the mechanisms that control this growth begin to be unravelled. For example, netrins could serve as chemattractants, the adhesion molecule L1 plays a crucial role in the control of axonal decussation at the level of the medulla, the ephrin B3-Eph A4 couple prevents the axons from crossing the midline. During development, the total number of pyramidal axons increases progressively and then decreases by regression of exuberant collaterals. ...
The growth of these axons is highly regulated and the mechanisms that control this growth begin to be unravelled. For example, …
The development of functional and directed corticomuscular connectivity during tonic ankle muscle contraction across childhood and adolescence.
Spedden ME, et al. Neuroimage 2019. PMID 30818025
However, little is known about the developmental trajectory of task-related corticomuscular connectivity relating to the voluntary control of the ankle muscles. ...These findings may contribute to the development of novel intervention strategies targeting improved sensorimotor control in children and adolescents with central motor disorders....
However, little is known about the developmental trajectory of task-related corticomuscular connectivity relating to the voluntary co …
Temporal and spatial distribution of growth-associated molecules and astroglial cells in the rat corticospinal tract during development.
Hsu JY, et al. J Neurosci Res 2005. PMID 15789366
To understand better the role of growth-promoting and -inhibiting molecules in the development of the corticospinal tract (CST), temporospatial expression of embryonic neural cell adhesion molecule (E-NCAM), growth-associated protein-43 (GAP-43), and chondroitin sulfate proteoglycan (CSPG) was studied in developing rats. ...Our study thus demonstrated dynamic changes of multiple growth-related molecules and astroglial environment that contribute to postnatal development of the CST....
To understand better the role of growth-promoting and -inhibiting molecules in the development of the corticospinal tract (CST …
Growth of the corticospinal tract and the development of placing reactions in the postnatal rat.
Donatelle JM. J Comp Neurol 1977. PMID 893740
The growth of corticospinal axons into the spinal cord has been demonstrated using the autoradiographic and the Fink-Heimer silver degeneration methods. ...While a causative relationship between the growth of corticospinal axons into the spinal cord and the development of placing has not been established, a close temporal relationship has been found between first: the appearance of fore-or hindlimb placing responses and the appearance of corticospinal axons within the spinal gray at the appropriate levels of the cord and second: between the completion of the primary growth of corticospinal axons at the light microscopic level and the maturation of the placing reactions....
The growth of corticospinal axons into the spinal cord has been demonstrated using the autoradiographic and the Fink-Heimer silver de …
Corticospinal tract development and spinal cord innervation differ between cervical and lumbar targets.
Kamiyama T, et al. J Neurosci 2015. PMID 25609632 Free PMC article.
The corticospinal (CS) tract is essential for voluntary movement, but what we know about the organization and development of the CS tract remains limited. ...This suggests that neuronal circuits involved in the CS tract to C7 are largely reorganized during development. By contrast, the cortical areas innervating L4 are limited to the conventional hindlimb area, and the cell distribution and density do not change during development. ...
The corticospinal (CS) tract is essential for voluntary movement, but what we know about the organization and development of the CS t …
Plasticity in One Hemisphere, Control From Two: Adaptation in Descending Motor Pathways After Unilateral Corticospinal Injury in Neonatal Rats
Wen TC, et al. Front Neural Circuits 2018. PMID 29706871 Free PMC article.
After injury to the corticospinal tract (CST) in early development there is large-scale adaptation of descending motor pathways. ...
After injury to the corticospinal tract (CST) in early development there is large-scale adaptation of descending motor pathways. ...
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