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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 21
1990 10
1991 8
1992 17
1993 14
1994 25
1995 35
1996 34
1997 52
1998 60
1999 68
2000 81
2001 100
2002 113
2003 95
2004 112
2005 117
2006 143
2007 94
2008 120
2009 156
2010 160
2011 184
2012 166
2013 177
2014 177
2015 163
2016 134
2017 135
2018 131
2019 52
2020 2
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2,742 results
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Page 1
Reporting of Multi-Arm Parallel-Group Randomized Trials: Extension of the CONSORT 2010 Statement.
Juszczak E, et al. JAMA 2019. PMID 31012939
IMPORTANCE: The quality of reporting of randomized clinical trials is suboptimal. In an era in which the need for greater research transparency is paramount, inadequate reporting hinders assessment of the reliability and validity of trial findings. The Consolidated Standards of Reporting Trials (CONSORT) 2010 Statement was developed to improve the reporting of randomized clinical trials, but the primary focus was on parallel-group trials with 2 groups. ...
IMPORTANCE: The quality of reporting of randomized clinical trials is suboptimal. In an era in which the need for greater research tr …
Randomized controlled trials in children's heart surgery in the 21st century: a systematic review.
Drury NE, et al. Eur J Cardiothorac Surg 2018. PMID 29186478 Free PMC article.
OBJECTIVES: Randomized controlled trials are the gold standard for evaluating health care interventions, yet are uncommon in children's heart surgery. ...METHODS: We searched MEDLINE, CENTRAL and LILACS, and manually screened retrieved references and systematic reviews to identify all randomized controlled trials reporting the effect of any intervention on the conduct or outcomes of heart surgery in children published in any language since January 2000; secondary publications and those reporting inseparable adult data were excluded. ...
OBJECTIVES: Randomized controlled trials are the gold standard for evaluating health care interventions, yet are uncommon in children …
Randomized controlled trials in plastic surgery: a 20-year review of reporting standards, methodologic quality, and impact.
Taghinia AH, et al. Plast Reconstr Surg 2008. PMID 18827662
The relative impact of randomized controlled trials in plastic surgery was compared with that in other specialties. RESULTS: A total of 163 randomized controlled trials were evaluated. ...Randomized controlled trials in plastic surgery had relatively lower impact as compared with randomized controlled trials in other specialties. ...
The relative impact of randomized controlled trials in plastic surgery was compared with that in other specialties. RESULTS: A total …
Absence of evidence is not evidence of absence
Altman DG and Bland JM. BMJ 1995. PMID 7647644 Free PMC article.
Randomized controlled clinical trials are conducted to determine whether differences of clinical importance exist between selected treatment regimens. ...
Randomized controlled clinical trials are conducted to determine whether differences of clinical importance exist between selected tr
Cluster-randomized controlled trials evaluating complex interventions in general practices are mostly ineffective: a systematic review.
Siebenhofer A, et al. J Clin Epidemiol 2018 - Review. PMID 29111470
OBJECTIVES: The aim of this study was to evaluate how frequently complex interventions are shown to be superior to routine care in general practice-based cluster-randomized controlled studies (c-RCTs) and to explore whether potential differences explain results that come out in favor of a complex intervention. ...
OBJECTIVES: The aim of this study was to evaluate how frequently complex interventions are shown to be superior to routine care in general p …
The quality of placebos used in randomized, controlled trials of lumbar and pelvic joint thrust manipulation-a systematic review.
Puhl AA, et al. Spine J 2017 - Review. PMID 27888138
STUDY DESIGN: This is a systematic review of randomized, placebo-controlled trials. METHODS: We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Index to Chiropractic Literature, and relevant bibliographies. We included randomized, placebo or sham-controlled trials where the index treatment was manually applied LP-SMT. There were no restrictions on the type of condition being investigated. ...
STUDY DESIGN: This is a systematic review of randomized, placebo-controlled trials. METHODS: We searched MEDLINE, EMBASE, Cochrane Ce …
Systematic review on the reporting quality of randomized controlled trials in patients with hepatitis B or C in China.
Zeng N, et al. Int J Infect Dis 2018 - Review. PMID 29138012 Free article.
BACKGROUND: The numbers of articles reporting randomized controlled trials (RCTs) on viral hepatitis in China have been increasing, but there have been few systematic studies evaluating the reporting quality of RCTs in this field. ...METHODS: Articles published between January 1991 and December 2015 were identified via the PubMed, MEDLINE, and Embase databases using the key words "randomized clinical trials", "treatment", "therapy", "hepatitis B", "HBV", "hepatitis C", "HCV", "China", and "Chinese". ...
BACKGROUND: The numbers of articles reporting randomized controlled trials (RCTs) on viral hepatitis in China have been increasing, b …
Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials
Schulz KF, et al. JAMA 1995. PMID 7823387
OBJECTIVE: To determine if inadequate approaches to randomized controlled trial design and execution are associated with evidence of bias in estimating treatment effects. ...
OBJECTIVE: To determine if inadequate approaches to randomized controlled trial design and execution are associated with evidence of …
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