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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1994 3
1995 2
1996 1
1997 12
1998 17
1999 35
2000 39
2001 39
2002 52
2003 105
2004 78
2005 114
2006 111
2007 82
2008 80
2009 110
2010 116
2011 110
2012 109
2013 126
2014 105
2015 106
2016 79
2017 82
2018 71
2019 47
2020 3
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1,624 results
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Page 1
Melanocortin-4 receptor-regulated energy homeostasis.
Krashes MJ, Lowell BB, Garfield AS. Krashes MJ, et al. Nat Neurosci. 2016 Feb;19(2):206-19. doi: 10.1038/nn.4202. Nat Neurosci. 2016. PMID: 26814590 Free PMC article. Review.
Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.
Collet TH, Dubern B, Mokrosinski J, Connors H, Keogh JM, Mendes de Oliveira E, Henning E, Poitou-Bernert C, Oppert JM, Tounian P, Marchelli F, Alili R, Le Beyec J, Pépin D, Lacorte JM, Gottesdiener A, Bounds R, Sharma S, Folster C, Henderson B, O'Rahilly S, Stoner E, Gottesdiener K, Panaro BL, Cone RD, Clément K, Farooqi IS, Van der Ploeg LHT. Collet TH, et al. Mol Metab. 2017 Oct;6(10):1321-1329. doi: 10.1016/j.molmet.2017.06.015. Epub 2017 Jul 8. Mol Metab. 2017. PMID: 29031731 Free PMC article. Clinical Trial.
Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.
Ayers KL, Glicksberg BS, Garfield AS, Longerich S, White JA, Yang P, Du L, Chittenden TW, Gulcher JR, Roy S, Fiedorek F, Gottesdiener K, Cohen S, North KE, Schadt EE, Li SD, Chen R, Van der Ploeg LHT. Ayers KL, et al. J Clin Endocrinol Metab. 2018 Jul 1;103(7):2601-2612. doi: 10.1210/jc.2018-00258. J Clin Endocrinol Metab. 2018. PMID: 29726959
Melanocortin-4 receptor regulation of pain.
Li ZX, Liu BW, He ZG, Xiang HB. Li ZX, et al. Biochim Biophys Acta Mol Basis Dis. 2017 Oct;1863(10 Pt A):2515-2522. doi: 10.1016/j.bbadis.2017.05.021. Epub 2017 May 26. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28552734 Free article. Review.
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
Kühnen P, Clément K, Wiegand S, Blankenstein O, Gottesdiener K, Martini LL, Mai K, Blume-Peytavi U, Grüters A, Krude H. Kühnen P, et al. N Engl J Med. 2016 Jul 21;375(3):240-6. doi: 10.1056/NEJMoa1512693. N Engl J Med. 2016. PMID: 27468060 Free article. Clinical Trial.
Melanocortin Receptor 4 Signaling Regulates Vertebrate Limb Regeneration.
Zhang M, Chen Y, Xu H, Yang L, Yuan F, Li L, Xu Y, Chen Y, Zhang C, Lin G. Zhang M, et al. Dev Cell. 2018 Aug 20;46(4):397-409.e5. doi: 10.1016/j.devcel.2018.07.021. Dev Cell. 2018. PMID: 30130530 Free PMC article.
A neural basis for melanocortin-4 receptor-regulated appetite.
Garfield AS, Li C, Madara JC, Shah BP, Webber E, Steger JS, Campbell JN, Gavrilova O, Lee CE, Olson DP, Elmquist JK, Tannous BA, Krashes MJ, Lowell BB. Garfield AS, et al. Nat Neurosci. 2015 Jun;18(6):863-71. doi: 10.1038/nn.4011. Epub 2015 Apr 27. Nat Neurosci. 2015. PMID: 25915476 Free PMC article.
Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy.
Litt MJ, Okoye GD, Lark D, Cakir I, Moore C, Barber MC, Atkinson J, Fessel J, Moslehi J, Cone RD. Litt MJ, et al. Elife. 2017 Aug 22;6:e28118. doi: 10.7554/eLife.28118. Elife. 2017. PMID: 28829041 Free PMC article.
RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals.
Chen KY, Muniyappa R, Abel BS, Mullins KP, Staker P, Brychta RJ, Zhao X, Ring M, Psota TL, Cone RD, Panaro BL, Gottesdiener KM, Van der Ploeg LH, Reitman ML, Skarulis MC. Chen KY, et al. J Clin Endocrinol Metab. 2015 Apr;100(4):1639-45. doi: 10.1210/jc.2014-4024. Epub 2015 Feb 12. J Clin Endocrinol Metab. 2015. PMID: 25675384 Free PMC article. Clinical Trial.
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