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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1975 1
1977 3
1978 27
1979 167
1980 275
1981 244
1982 299
1983 263
1984 318
1985 459
1986 489
1987 607
1988 624
1989 848
1990 1037
1991 1224
1992 1131
1993 1198
1994 1238
1995 1499
1996 1686
1997 1770
1998 1842
1999 1781
2000 1931
2001 1841
2002 1769
2003 1771
2004 2203
2005 2296
2006 2704
2007 2910
2008 3265
2009 3648
2010 3485
2011 3689
2012 3680
2013 3295
2014 3349
2015 3367
2016 2838
2017 3064
2018 3116
2019 1283
2020 26
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69,164 results
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Page 1
Pattern recognition receptors and inflammation.
Takeuchi O and Akira S. Cell 2010 - Review. PMID 20303872 Free article.
The initial sensing of infection is mediated by innate pattern recognition receptors (PRRs), which include Toll-like receptors, RIG-I-like receptors, NOD-like receptors, and C-type lectin receptors. ...
The initial sensing of infection is mediated by innate pattern recognition receptors (PRRs), which include Toll-like receptors
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity.
Kawai T and Akira S. Immunity 2011 - Review. PMID 21616434 Free article.
Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that play a central role in host cell recognition and responses to microbial pathogens. TLR-mediated recognition of components derived from a wide range of pathogens and their role in the subsequent initiation of innate immune responses is widely accepted; however, the recent discovery of non-TLR PRRs, such as C-type lectin receptors, NOD-like receptors, and RIG-I-like receptors, suggests that many aspects of innate immunity are more sophisticated and complex. ...
Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that play a central role in host cell rec …
Universal CARs, universal T cells, and universal CAR T cells
Zhao J, et al. J Hematol Oncol 2018 - Review. PMID 30482221 Free PMC article.
Currently, the two approved T cell products with chimeric antigen receptors (CAR) are from autologous T cells. These CAR T cells approved for clinical use must be generated on a custom-made basis. ...
Currently, the two approved T cell products with chimeric antigen receptors (CAR) are from autologous T cells. These CAR T cells appr …
Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells.
Kim N and Kim HS. Front Immunol 2018 - Review. PMID 30250471 Free PMC article.
These emerging targets include natural killer (NK) cell-directed checkpoint receptors (KIR and CD94/NKG2A) as well as the NK- and T cell-expressed checkpoints TIM-3, TIGIT, CD96, and LAG-3. ...
These emerging targets include natural killer (NK) cell-directed checkpoint receptors (KIR and CD94/NKG2A) as well as the NK- and T c …
Tuning Natural Killer Cell Anti-multiple Myeloma Reactivity by Targeting Inhibitory Signaling via KIR and NKG2A
Mahaweni NM, et al. Front Immunol 2018 - Review. PMID 30564241 Free PMC article.
NK cells express killer immunoglobulin-like receptors (KIRs) and the NKG2A receptor important for NK cells education as well as providing inhibitory signals upon encountering HLA-expressing target cells. ...
NK cells express killer immunoglobulin-like receptors (KIRs) and the NKG2A receptor important for NK cells education as well as provi …
Assembly and localization of Toll-like receptor signalling complexes
Gay NJ, et al. Nat Rev Immunol 2014 - Review. PMID 25060580
Signal transduction by the Toll-like receptors (TLRs) is central to host defence against many pathogenic microorganisms and also underlies a large burden of human disease. ...
Signal transduction by the Toll-like receptors (TLRs) is central to host defence against many pathogenic microorganisms and also unde …
Regulation of adaptive immunity by the innate immune system
Iwasaki A and Medzhitov R. Science 2010 - Review. PMID 20075244 Free PMC article.
Twenty years after the proposal that pattern recognition receptors detect invasion by microbial pathogens, the field of immunology has witnessed several discoveries that have elucidated receptors and signaling pathways of microbial recognition systems and how they control the generation of T and B lymphocyte-mediated immune responses. ...
Twenty years after the proposal that pattern recognition receptors detect invasion by microbial pathogens, the field of immunology
PRR Function of Innate Immune Receptors in Recognition of Bacteria or Bacterial Ligands.
Gulati A, et al. Adv Exp Med Biol 2018 - Review. PMID 30637703
Towards this, the host innate immune system employs pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs), nucleotide-binding leucine-rich repeat-containing receptors (NLRs) and scavenger receptors (SRs) present mostly in innate immune cells. ...This review is focussed mainly on their role in the bacterial recognition and how these receptors play a role in eliciting an immune response against bacteria in the host....
Towards this, the host innate immune system employs pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs), n …
69,164 results
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