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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1997 1
1998 2
1999 1
2001 1
2002 3
2003 3
2004 16
2005 5
2006 13
2007 11
2008 24
2009 24
2010 32
2011 28
2012 17
2013 24
2014 27
2015 26
2016 34
2017 24
2018 25
2019 15
2020 0
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318 results
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Page 1
Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway.
Herbertz S, Sawyer JS, Stauber AJ, Gueorguieva I, Driscoll KE, Estrem ST, Cleverly AL, Desaiah D, Guba SC, Benhadji KA, Slapak CA, Lahn MM. Herbertz S, et al. Drug Des Devel Ther. 2015 Aug 10;9:4479-99. doi: 10.2147/DDDT.S86621. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 26309397 Free PMC article. Review.
Heterobicyclic inhibitors of transforming growth factor beta receptor I (TGFβRI).
Harikrishnan LS, Warrier J, Tebben AJ, Tonukunuru G, Madduri SR, Baligar V, Mannoori R, Seshadri B, Rahaman H, Arunachalam PN, Dikundwar AG, Fink BE, Fargnoli J, Fereshteh M, Fan Y, Lippy J, Ho CP, Wautlet B, Sheriff S, Ruzanov M, Borzilleri RM. Harikrishnan LS, et al. Bioorg Med Chem. 2018 Mar 1;26(5):1026-1034. doi: 10.1016/j.bmc.2018.01.014. Epub 2018 Jan 31. Bioorg Med Chem. 2018. PMID: 29422332
Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells.
Spender LC, Ferguson GJ, Liu S, Cui C, Girotti MR, Sibbet G, Higgs EB, Shuttleworth MK, Hamilton T, Lorigan P, Weller M, Vincent DF, Sansom OJ, Frame M, Dijke PT, Marais R, Inman GJ. Spender LC, et al. Oncotarget. 2016 Dec 13;7(50):81995-82012. doi: 10.18632/oncotarget.13226. Oncotarget. 2016. PMID: 27835901 Free PMC article.
Design, synthesis and evaluation of small molecule imidazo[2,1-b][1,3,4]thiadiazoles as inhibitors of transforming growth factor-β type-I receptor kinase (ALK5).
Patel HM, Sing B, Bhardwaj V, Palkar M, Shaikh MS, Rane R, Alwan WS, Gadad AK, Noolvi MN, Karpoormath R. Patel HM, et al. Eur J Med Chem. 2015 Mar 26;93:599-613. doi: 10.1016/j.ejmech.2014.09.002. Epub 2014 Sep 3. Eur J Med Chem. 2015. PMID: 25234355
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