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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1953 1
1955 1
1956 3
1957 21
1958 15
1959 11
1962 1
1963 2
1965 13
1966 47
1967 95
1968 113
1969 115
1970 117
1971 142
1972 142
1973 225
1974 186
1975 171
1976 190
1977 155
1978 169
1979 186
1980 192
1981 230
1982 205
1983 250
1984 244
1985 313
1986 253
1987 246
1988 243
1989 289
1990 284
1991 297
1992 303
1993 316
1994 320
1995 280
1996 278
1997 275
1998 340
1999 327
2000 340
2001 344
2002 329
2003 357
2004 368
2005 416
2006 394
2007 425
2008 429
2009 406
2010 398
2011 429
2012 389
2013 374
2014 320
2015 282
2016 255
2017 220
2018 192
2019 49
2020 0
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13,424 results
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Page 1
[Effects of morphine on pupillary light reflex in monkeys].
Meng ZQ, et al. Dongwuxue Yanjiu 2010. PMID 20672416 Chinese. Free article.
Thus, the properties of pupillary light reflex could serve as an indicator for drug abuse detection. However, the effect of drug abuse on pupillary light reflex is till unclear. To assess the effects of addictive drugs on pupillary light reflex quantificationally, in the present study, we examined the effects of morphine on pupil diameter and pupillary light reflex in rhesus monkeys. ...
Thus, the properties of pupillary light reflex could serve as an indicator for drug abuse detection. However, the effect of …
[Hyperexplexia]
Chevrel J, et al. Arch Pediatr 1995 - Review. PMID 7640741 French.
Hyperexplexia is a disease of neonatal onset characterized by an exaggerated startle reflex. Early diagnosis is important to rule out epilepsy. Clinical findings are mainly hypertony and generalized startle reflex which is exaggerated by tiredness and some exogenous stimuli. ...
Hyperexplexia is a disease of neonatal onset characterized by an exaggerated startle reflex. Early diagnosis is important to rule out …
Effects of sevoflurane and propofol on the nociceptive withdrawal reflex and on the H reflex.
Baars JH, et al. Anesthesiology 2009. PMID 19512883
METHODS: In a crossover design, the authors compared in 13 volunteers the effects of sevoflurane and propofol on the amplitudes of the H reflex, which is mediated exclusively in the ventral horn and a withdrawal reflex (RIII Reflex), which integrates dorsal and ventral horn function. ...Sevoflurane produces a larger inhibitory effect on the H reflex than propofol, which confirms that the ventral horn is a more important target for volatile anesthetics, whereas effects of propofol on this site of action are rather limited. ...
METHODS: In a crossover design, the authors compared in 13 volunteers the effects of sevoflurane and propofol on the amplitudes of th …
[Effects of cocaine on prepulse inhibition of the startle response].
Arenas MC, et al. Rev Neurol 2017 - Review. PMID 29178109 Spanish. Free article.
DEVELOPMENT: A comprehensive review is carried out, covering both clinical and preclinical studies with animal models that have evaluated the effects of cocaine exposure on the PPI paradigm. ...However, the effects of cocaine on PPI appear to depend on the baseline levels of PPI shown by the individual. Thus, since a deficit in PPI has been associated with a greater vulnerability to developing mental pathologies such as schizophrenia, PPI level in subjects could be considered as a biomarker of psychiatric vulnerability. ...
DEVELOPMENT: A comprehensive review is carried out, covering both clinical and preclinical studies with animal models that have evaluated th …
Baclofen and velocity storage: a model of the effects of the drug on the vestibulo-ocular reflex in the rhesus monkey.
Cohen B, et al. J Physiol 1987. PMID 3446808 Free PMC article.
Each aspect of nystagmus that is dependent on the velocity-storage mechanism in the vestibulo-ocular reflex (v.o.r.) was altered by the drug: (a) Baclofen reduced the dominant time constant of the v.o.r. in a dose-dependent manner up to 5 mg/kg, the highest dosage used. ...This indicates that it is possible to use baclofen to manipulate the dominant time constant of the v.o.r. and of o.k.a.n. in relative isolation from effects on other oculomotor components. 3. ...
Each aspect of nystagmus that is dependent on the velocity-storage mechanism in the vestibulo-ocular reflex (v.o.r.) was altered by t …
Effects of caffeine on sensorimotor gating of the startle reflex in normal control subjects: impact of caffeine intake and withdrawal.
Swerdlow NR, et al. Psychopharmacology (Berl) 2000 - Clinical Trial. PMID 11026744
RESULTS: There were significant effects of caffeine and/or caffeine withdrawal on several self-rating and autonomic measures, and on startle reflex habituation, but not on acoustic or tactile startle magnitude or PPI. ...CONCLUSIONS: While a physiologically active dose of caffeine has no simple effects on PPI in normal humans, both withdrawal states and normal levels of caffeine consumption may be important factors in understanding this drug's effects on sensorimotor gating....
RESULTS: There were significant effects of caffeine and/or caffeine withdrawal on several self-rating and autonomic measures, and on …
Does trait anxiety influence effects of oxytocin on eye-blink startle reactivity? A randomized, double-blind, placebo-controlled crossover study.
Schumacher S, et al. PLoS One 2018 - Clinical Trial. PMID 29300752 Free PMC article.
CONCLUSION: Results indicate that effects of oxytocin on defense system activation depend on individual differences in trait anxiety. Trait anxiety may be an important moderator variable that should be considered in human studies on oxytocin effects....
CONCLUSION: Results indicate that effects of oxytocin on defense system activation depend on individual differences in trait anxiety. …
Effects of alcohol on the acoustic reflex threshold in the chinchilla.
Uhles ML, et al. Acta Otolaryngol 2000. PMID 10958405
The effect of ethanol on the acoustic reflex threshold was examined in a repeated measure design study in six chinchillas. Each subject was weighed and orally administered the control (water) at a dosage of 7.5 ml/kg. Commencing 1 h after alcohol ingestion, the acoustic middle ear reflex measures (AMRs) were taken every other hour, for a total of four recording sessions. ...
The effect of ethanol on the acoustic reflex threshold was examined in a repeated measure design study in six chinchillas. Each subje …
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