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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1974 1
1975 16
1976 34
1977 36
1978 43
1979 69
1980 59
1981 61
1982 55
1983 83
1984 80
1985 123
1986 99
1987 121
1988 104
1989 112
1990 127
1991 114
1992 133
1993 142
1994 99
1995 98
1996 84
1997 98
1998 90
1999 92
2000 90
2001 97
2002 93
2003 95
2004 73
2005 94
2006 82
2007 101
2008 58
2009 70
2010 59
2011 59
2012 73
2013 58
2014 50
2015 54
2016 50
2017 40
2018 24
2019 9
2020 2
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3,397 results
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Page 1
Biomarkers of Nutrition for Development (BOND)-Vitamin A Review
Tanumihardjo SA, et al. J Nutr 2016 - Review. PMID 27511929 Free PMC article.
Furthermore, serum retinol concentrations are depressed during infection and inflammation because retinol-binding protein (RBP) is a negative acute-phase reactant, which makes status assessment challenging. Thus, this review describes the clinical and functional indicators related to eye health and biochemical biomarkers of vitamin A status (i.e., serum retinol, RBP, breast-milk retinol, dose-response tests, isotope dilution methodology, and serum retinyl esters). ...
Furthermore, serum retinol concentrations are depressed during infection and inflammation because retinol-binding prote …
Retinoids: a journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effects
Khalil S, et al. J Dermatolog Treat 2017 - Review. PMID 28318351
Inside the body, retinoids bind to several classes of proteins including retinoid-binding proteins and retinoid nuclear receptors. ...
Inside the body, retinoids bind to several classes of proteins including retinoid-binding proteins and retinoid nuclear …
Retinol-Binding Protein Interferes with Transthyretin-Mediated β-Amyloid Aggregation Inhibition.
Mangrolia P and Murphy RM. Biochemistry 2018. PMID 30024734 Free PMC article.
TTR is a homotetrameric protein that circulates in blood and cerebrospinal fluid; its normal physiological role is as a carrier for thyroxine and retinol-binding protein (RBP). RBP forms a complex with retinol, and the holoprotein (hRBP) binds with high affinity to TTR. In this study, the role of TTR ligands in TTR-mediated inhibition of Aβ aggregation was investigated. hRBP strongly reduced the ability of TTR to inhibit Aβ aggregation. ...
TTR is a homotetrameric protein that circulates in blood and cerebrospinal fluid; its normal physiological role is as a carrier for thyroxin …
Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils.
Zhan B, et al. PLoS Negl Trop Dis 2018. PMID 30296268 Free PMC article.
Parasitic nematodes produce an unusual class of fatty acid and retinol (FAR)-binding proteins that may scavenge host fatty acids and retinoids. Two FARs from Brugia malayi (Bm-FAR-1 and Bm-FAR-2) were expressed as recombinant proteins, and their ligand binding, structural characteristics, and immunogenicities examined. ...
Parasitic nematodes produce an unusual class of fatty acid and retinol (FAR)-binding proteins that may scavenge host fa …
Signaling by retinol and its serum binding protein.
Noy N. Prostaglandins Leukot Essent Fatty Acids 2015. PMID 25481334 Free PMC article.
Vitamin A, retinol, circulates in blood bound to retinol-binding protein (RBP) which, in turn, associates with transthyretin (TTR) to form a retinol-RBP-TTR ternary complex. ...STRA6-mediated retinol transport and cell signaling are critically inter-dependent, and they both require the presence of cellular retinol-binding protein 1 (CRBP1), an intracellular retinol acceptor, as well as a retinol-metabolizing enzyme such as lecithin:retinol acyltransferase (LRAT). ...
Vitamin A, retinol, circulates in blood bound to retinol-binding protein (RBP) which, in turn, associates with transthy …
Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection.
Derebe MG, et al. Elife 2014. PMID 25073702 Free PMC article.
Here we show that mouse and human SAAs are retinol binding proteins. Mouse and human SAAs bound retinol with nanomolar affinity, were associated with retinol in vivo, and limited the bacterial burden in tissues after acute infection. ...Our results thus identify SAAs as a family of microbe-inducible retinol binding proteins, reveal a unique protein architecture involved in retinol binding, and suggest how retinol is circulated during infection....
Here we show that mouse and human SAAs are retinol binding proteins. Mouse and human SAAs bound retinol with nan …
Transthyretin: a multifaceted protein
Vieira M and Saraiva MJ. Biomol Concepts 2014 - Review. PMID 25372741
The aim of this review is to stress the relevance of TTR, besides its well-known role on transport of thyroxine and retinol-binding protein....
The aim of this review is to stress the relevance of TTR, besides its well-known role on transport of thyroxine and retinol-bindin
Vitamin A and retinol-binding protein deficiency among chronic liver disease patients.
Chaves GV, et al. Nutrition 2015. PMID 25837210
The aim in this study was to assess levels of serum retinol and retinol-binding protein (RBP) as well as liver vitamin A stores in the presence of liver cirrhosis and hepatocellular carcinoma. ...CONCLUSIONS: Our findings suggest serum retinol and RBP are relevant as indicators of vitamin A nutritional status in the presence of CLD. ...
The aim in this study was to assess levels of serum retinol and retinol-binding protein (RBP) as well as liver vitamin …
Retinol-binding site in interphotoreceptor retinoid-binding protein (IRBP): a novel hydrophobic cavity.
Gonzalez-Fernandez F, et al. Invest Ophthalmol Vis Sci 2009. PMID 19608538 Free PMC article.
Binding of 11-cis and all-trans retinol were observed in titrations monitoring retinol fluorescence enhancement, quenching of tryptophan fluorescence, and energy transfer. ...Oleic acid inhibited the binding of 11-cis and all-trans retinol in an apparent noncompetitive manner. CONCLUSIONS: The binding site for 11-cis and all-trans retinol is a novel hydrophobic cavity that is highly restrictive and probably distinct from the long chain fatty acid-binding site....
Binding of 11-cis and all-trans retinol were observed in titrations monitoring retinol fluorescence enhancement, quench
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