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720 results

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Quoted phrase not found in phrase index: "Rheumatoid arthritis aggravated"
Page 1
Fusobacterium nucleatum aggravates rheumatoid arthritis through FadA-containing outer membrane vesicles.
Hong M, Li Z, Liu H, Zheng S, Zhang F, Zhu J, Shi H, Ye H, Chou Z, Gao L, Diao J, Zhang Y, Zhang D, Chen S, Zhou H, Li J. Hong M, et al. Cell Host Microbe. 2023 May 10;31(5):798-810.e7. doi: 10.1016/j.chom.2023.03.018. Epub 2023 Apr 12. Cell Host Microbe. 2023. PMID: 37054714 Free article.
Rheumatoid arthritis (RA) is an autoimmune disorder that has been associated with the gut microbiota. ...Here, we observed that Fusobacterium nucleatum is enriched in RA patients and positively associated with RA severity. F. nucleatum similarly aggravates
Rheumatoid arthritis (RA) is an autoimmune disorder that has been associated with the gut microbiota. ...Here, we observed tha
Identification of immune-related genes in diagnosing atherosclerosis with rheumatoid arthritis through bioinformatics analysis and machine learning.
Liu F, Huang Y, Liu F, Wang H. Liu F, et al. Front Immunol. 2023 Mar 9;14:1126647. doi: 10.3389/fimmu.2023.1126647. eCollection 2023. Front Immunol. 2023. PMID: 36969166 Free PMC article.
BACKGROUND: Increasing evidence has proven that rheumatoid arthritis (RA) can aggravate atherosclerosis (AS), and we aimed to explore potential diagnostic genes for patients with AS and RA. ...
BACKGROUND: Increasing evidence has proven that rheumatoid arthritis (RA) can aggravate atherosclerosis (AS), and we ai …
Metabolic Control of Autoimmunity and Tissue Inflammation in Rheumatoid Arthritis.
Qiu J, Wu B, Goodman SB, Berry GJ, Goronzy JJ, Weyand CM. Qiu J, et al. Front Immunol. 2021 Apr 2;12:652771. doi: 10.3389/fimmu.2021.652771. eCollection 2021. Front Immunol. 2021. PMID: 33868292 Free PMC article. Review.
Like other autoimmune diseases, rheumatoid arthritis (RA) develops in distinct stages, with each phase of disease linked to immune cell dysfunction. ...Early in their life cycle, RA T cells fail to repair mitochondrial DNA, resulting in a malfunctioning metabolic ma …
Like other autoimmune diseases, rheumatoid arthritis (RA) develops in distinct stages, with each phase of disease linked to im …
Recent advances on signaling pathways and their inhibitors in rheumatoid arthritis.
Liu S, Ma H, Zhang H, Deng C, Xin P. Liu S, et al. Clin Immunol. 2021 Sep;230:108793. doi: 10.1016/j.clim.2021.108793. Epub 2021 Jul 6. Clin Immunol. 2021. PMID: 34242749 Review.
Rheumatoid arthritis (RA) is characterized by systemic synovitis leading to joint destruction in which imbalances in pro-inflammatory and anti-inflammatory cytokines promote the induction of autoimmunity. Some pro-inflammatory cytokines can trigger the signaling pat
Rheumatoid arthritis (RA) is characterized by systemic synovitis leading to joint destruction in which imbalances in pro-infla
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, Weng W, Zhao J, Shi X, Chen J, Dong B, Zhong S, Ren J, Li Y, Wang J, Zhang J, Sun J, Xu H, Lu Y, Brand D, Zheng SG, Pan Y. Liu Y, et al. Redox Biol. 2024 Feb;69:103008. doi: 10.1016/j.redox.2023.103008. Epub 2023 Dec 20. Redox Biol. 2024. PMID: 38142586 Free PMC article.
Focal iron overload is frequently observed in patients with rheumatoid arthritis (RA), yet its functional significance remains elusive. Herein, we report that iron deposition in lesion aggravates arthritis by inducing macrophage ferroptosis. ...Of note …
Focal iron overload is frequently observed in patients with rheumatoid arthritis (RA), yet its functional significance remains …
The Effects of Vitamin D on Immune System and Inflammatory Diseases.
Ao T, Kikuta J, Ishii M. Ao T, et al. Biomolecules. 2021 Nov 3;11(11):1624. doi: 10.3390/biom11111624. Biomolecules. 2021. PMID: 34827621 Free PMC article. Review.
Recent epidemiological evidence has indicated a significant association between vitamin D deficiency and an increased incidence, or aggravation, of infectious diseases and inflammatory autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythema …
Recent epidemiological evidence has indicated a significant association between vitamin D deficiency and an increased incidence, or aggra
miR-144-3p aggravated cartilage injury in rheumatoid arthritis by regulating BMP2/PI3K/Akt axis.
Mo ML, Jiang JM, Long XP, Xie LH. Mo ML, et al. Mod Rheumatol. 2022 Oct 15;32(6):1064-1076. doi: 10.1093/mr/roab105. Mod Rheumatol. 2022. PMID: 34850093
OBJECTIVES: Present study aimed to illustrate the role of miR-144-3p in rheumatoid arthritis (RA). METHODS: N1511 chondrocytes were stimulated by interleukin (IL)-1beta to mimic RA injury model in vitro. ...CONCLUSION: Collectively, miR-144-3p could aggravate
OBJECTIVES: Present study aimed to illustrate the role of miR-144-3p in rheumatoid arthritis (RA). METHODS: N1511 chondrocytes …
Infectious mimics of rheumatoid arthritis.
Sharma V, Sharma A. Sharma V, et al. Best Pract Res Clin Rheumatol. 2022 Mar;36(1):101736. doi: 10.1016/j.berh.2021.101736. Epub 2021 Dec 31. Best Pract Res Clin Rheumatol. 2022. PMID: 34974970 Review.
Rheumatoid arthritis (RA) can have various infectious mimics. As immunosuppressive agents used in treatment can aggravate the underlying infections, correct diagnosis of RA and ruling out infections is important. Numerous viral infections (Parvovirus B19, Hep
Rheumatoid arthritis (RA) can have various infectious mimics. As immunosuppressive agents used in treatment can aggravate
Ultrasmall iron-quercetin metal natural product nanocomplex with antioxidant and macrophage regulation in rheumatoid arthritis.
Han Z, Gao X, Wang Y, Cheng S, Zhong X, Xu Y, Zhou X, Zhang Z, Liu Z, Cheng L. Han Z, et al. Acta Pharm Sin B. 2023 Apr;13(4):1726-1739. doi: 10.1016/j.apsb.2022.11.020. Epub 2022 Nov 22. Acta Pharm Sin B. 2023. PMID: 37139421 Free PMC article.
Oxidative stress, due to the disruption of the balance between reactive oxygen species (ROS) generation and the antioxidant defense system, plays an important role in the pathogenesis of rheumatoid arthritis (RA). Excessive ROS leads to the loss of biological molecu …
Oxidative stress, due to the disruption of the balance between reactive oxygen species (ROS) generation and the antioxidant defense system, …
An ROS-responsive artesunate prodrug nanosystem co-delivers dexamethasone for rheumatoid arthritis treatment through the HIF-1alpha/NF-kappaB cascade regulation of ROS scavenging and macrophage repolarization.
Li Y, Liang Q, Zhou L, Cao Y, Yang J, Li J, Liu J, Bi J, Liu Y. Li Y, et al. Acta Biomater. 2022 Oct 15;152:406-424. doi: 10.1016/j.actbio.2022.08.054. Epub 2022 Aug 30. Acta Biomater. 2022. PMID: 36055613
The signaling cascade between nuclear factor-kappa B (NF-kappaB) and hypoxia-inducible factor-1alpha (HIF-1alpha) can be activated by proinflammatory M1 macrophages in rheumatoid arthritis (RA), which produces reactive oxygen species (ROS) and enhances M1 macrophage …
The signaling cascade between nuclear factor-kappa B (NF-kappaB) and hypoxia-inducible factor-1alpha (HIF-1alpha) can be activated by proinf …
720 results