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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 4
1963 1
1964 1
1974 1
1975 16
1976 21
1977 39
1978 23
1979 25
1980 28
1981 24
1982 30
1983 35
1984 42
1985 52
1986 59
1987 85
1988 74
1989 68
1990 91
1991 69
1992 51
1993 67
1994 65
1995 81
1996 82
1997 70
1998 111
1999 164
2000 231
2001 256
2002 359
2003 433
2004 527
2005 533
2006 551
2007 542
2008 545
2009 617
2010 650
2011 785
2012 761
2013 813
2014 854
2015 770
2016 631
2017 498
2018 392
2019 135
2020 2
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11,289 results
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Page 1
Ribavirin for treating Crimean Congo haemorrhagic fever.
Johnson S, et al. Cochrane Database Syst Rev 2018 - Review. PMID 29869797 Free PMC article.
There is uncertainty and controversy about treating CCHF with the antiviral drug ribavirin. OBJECTIVES: To assess the effects of ribavirin for treating people with Crimean Congo haemorrhagic fever. ...One non-randomized study assessed mortality in people receiving ribavirin and supportive care within four days or less from symptom onset compared to after four days since symptom onset: mortality was lower in the group receiving early supportive care and ribavirin, but it is not possible to distinguish between the effects of ribavirin and early supportive medical care alone.In the subsidiary analysis, 18 studies compared people receiving ribavirin with those not receiving ribavirin. ...
There is uncertainty and controversy about treating CCHF with the antiviral drug ribavirin. OBJECTIVES: To assess the effects of r
Hepatitis E virus infection
Kamar N, et al. Nat Rev Dis Primers 2017 - Review. PMID 29154369
Management of immunocompromised individuals involves lowering the dose of immunosuppressive drugs and/or treatment with the antiviral agent ribavirin....
Management of immunocompromised individuals involves lowering the dose of immunosuppressive drugs and/or treatment with the antiviral agent …
Determining Ribavirin's mechanism of action against Lassa virus infection.
Carrillo-Bustamante P, et al. Sci Rep 2017. PMID 28916737 Free PMC article.
Ribavirin is a broad spectrum antiviral which inhibits Lassa virus (LASV) replication in vitro but exhibits a minor effect on viremia in vivo. ...Here, we used an interdisciplinary approach combining mathematical models and experimental data in LASV-infected mice that were treated with ribavirin alone or in combination with the drug favipiravir to explore different putative mechanisms of action for ribavirin. ...
Ribavirin is a broad spectrum antiviral which inhibits Lassa virus (LASV) replication in vitro but exhibits a minor effect on viremia
Efficacy of Sofosbuvir and Velpatasvir, With and Without Ribavirin, in Patients With Hepatitis C Virus Genotype 3 Infection and Cirrhosis.
Esteban R, et al. Gastroenterology 2018 - Clinical Trial. PMID 29958855
It is unclear whether adding ribavirin to this treatment regimen increases SVRs in patients with genotype 3 HCV infection and cirrhosis. ...Patients were assigned to groups given sofosbuvir and velpatasvir for 12 weeks (n = 101) or sofosbuvir and velpatasvir plus ribavirin for 12 weeks (n = 103). ...
It is unclear whether adding ribavirin to this treatment regimen increases SVRs in patients with genotype 3 HCV infection and cirrhos …
Case report: Ribavirin and vitamin A in a severe case of measles.
Bichon A, et al. Medicine (Baltimore) 2017. PMID 29390321 Free PMC article.
OUTCOMES: The evolution was good after administration of intramuscular vitamin A as well as intravenous ribavirin. LESSONS: Measles remains a fatal and serious disease. The early use of ribavirin and vitamin A shows significant improvements regarding morbimortality and should be systematic in severe cases....
OUTCOMES: The evolution was good after administration of intramuscular vitamin A as well as intravenous ribavirin. LESSONS: Measles r …
Comparative effectiveness of aerosolized versus oral ribavirin for the treatment of respiratory syncytial virus infections: A single-center retrospective cohort study and review of the literature.
Trang TP, et al. Transpl Infect Dis 2018 - Review. PMID 29360277
In January 2015, our institution switched from aerosolized to oral ribavirin (RBV) for primary treatment of RSV infection among high-risk immunocompromised adult patients. ...
In January 2015, our institution switched from aerosolized to oral ribavirin (RBV) for primary treatment of RSV infection among high- …
Sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 hepatitis C who failed direct-acting antivirals.
Izumi N, et al. Hepatol Int 2018 - Clinical Trial. PMID 30030720 Free PMC article.
In this Phase 3 study, we evaluated sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 HCV infection who previously received DAAs. ...CONCLUSION: Sofosbuvir-velpatasvir plus ribavirin was highly effective and well tolerated in Japanese patients who previously failed a DAA-based regimen. ...
In this Phase 3 study, we evaluated sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 HCV infection who …
Growth inhibition and transcriptional effects of ribavirin in lymphoma.
Dominguez-Gomez G, et al. Oncol Rep 2019. PMID 31322273
To further investigate the potential of ribavirin as an anticancer treatment for lymphoma, the tumor‑suppressive effects of ribavirin were analyzed in lymphoma cell lines. ...Our results provide insight into the anti‑lymphoma potential of ribavirin; however, further investigations in preclinical and clinical studies are required to determine the effectiveness of ribavirin as a therapeutic agent for treating lymphoma....
To further investigate the potential of ribavirin as an anticancer treatment for lymphoma, the tumor‑suppressive effects of ribavi
Efficacy of ribavirin against malignant glioma cell lines: Follow-up study.
Ochiai Y, et al. Oncol Rep 2018. PMID 29251333 Free PMC article.
Furthermore, the potential antitumor efficacy of ribavirin has attracted increasing interest. Recently, we demonstrated a dose-dependent antitumor effect of ribavirin for seven types of malignant glioma cell lines. ...Dotted accumulations of γH2AX were found in the nuclei and increased levels of ATM and phosphorylated ATM protein expression were also observed following ribavirin treatment (10 µM of ribavirin, clinical relevant concentration) in both the malignant glioma cells, indicating double-strand breaks as one possible mechanism underlying the antitumor effect of ribavirin. ...
Furthermore, the potential antitumor efficacy of ribavirin has attracted increasing interest. Recently, we demonstrated a dose-depend …
Efficacy and safety of sofosbuvir-velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial.
Takehara T, et al. J Gastroenterol 2019 - Clinical Trial. PMID 30203225 Free PMC article.
Most adverse events (AEs) were consistent with clinical sequelae of advanced liver disease or known toxicities of ribavirin. ...Ribavirin did not improve efficacy but increased toxicity....
Most adverse events (AEs) were consistent with clinical sequelae of advanced liver disease or known toxicities of ribavirin. ...Ri
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