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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 4
1963 4
1964 8
1965 3
1966 1
1972 1
1973 3
1974 46
1975 212
1976 250
1977 259
1978 248
1979 309
1980 213
1981 234
1982 198
1983 195
1984 214
1985 183
1986 173
1987 201
1988 245
1989 217
1990 230
1991 249
1992 231
1993 293
1994 262
1995 283
1996 267
1997 261
1998 287
1999 313
2000 306
2001 340
2002 339
2003 317
2004 331
2005 368
2006 343
2007 362
2008 360
2009 366
2010 421
2011 397
2012 397
2013 413
2014 439
2015 413
2016 363
2017 411
2018 334
2019 180
2020 6
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12,640 results
Results by year
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Page 1
Ribosomal Proteins Control Tumor Suppressor Pathways in Response to Nucleolar Stress.
Lessard F, et al. Bioessays 2019 - Review. PMID 30706966
Ribosome biogenesis includes the making and processing of ribosomal RNAs, the biosynthesis of ribosomal proteins from their mRNAs in the cytosol and their transport to the nucleolus to assemble pre-ribosomal particles. ...Several ribosomal proteins can activate the p53 tumor suppressor pathway but cells without p53 can still arrest their proliferation in response to an imbalance between ribosomal proteins and mature rRNA production. ...
Ribosome biogenesis includes the making and processing of ribosomal RNAs, the biosynthesis of ribosomal proteins from t …
Structural Aspects of Ribosomal RNA Recognition by Ribosomal Proteins.
Nikulin AD. Biochemistry (Mosc) 2018 - Review. PMID 29544435 Free article.
This review is focused on the structural aspects of interaction between ribosomal proteins and ribosomal RNA in bacterial ribosomes and complexes of ribosomal proteins with specific fragments of ribosomal RNA. Special attention is given to the recognition of specific spatial architecture of the double-stranded ribosomal RNA by ribosomal proteins and to the role of unstructured protein regions in stabilization of distant ribosomal RNA segments....
This review is focused on the structural aspects of interaction between ribosomal proteins and ribosomal RNA in bacteri …
Phosphorylation of the Ribosomal Protein RPL12/uL11 Affects Translation during Mitosis.
Imami K, et al. Mol Cell 2018. PMID 30220558 Free article.
Until now, research mainly focused on differences in core ribosomal proteins and associated factors. The effect of posttranslational modifications has not been studied systematically. ...Together, our results show that posttranslational modification of ribosomal proteins can regulate translation....
Until now, research mainly focused on differences in core ribosomal proteins and associated factors. The effect of posttransla …
Revising the Structural Diversity of Ribosomal Proteins Across the Three Domains of Life.
Melnikov S, et al. Mol Biol Evol 2018. PMID 29529322 Free PMC article.
Ribosomal proteins are indispensable components of a living cell, and yet their structures are remarkably diverse in different species. ...We then illustrate that these variations reflect an apparent adaptation of ribosomal proteins to the specific environments and lifestyles of living species. ...
Ribosomal proteins are indispensable components of a living cell, and yet their structures are remarkably diverse in different
Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis
Khajuria RK, et al. Cell 2018. PMID 29551269 Free PMC article.
By studying a genetic blood disorder, Diamond-Blackfan anemia (DBA), where the majority of mutations affect ribosomal proteins and the erythroid lineage is selectively perturbed, we are able to gain mechanistic insight into how lineage commitment is programmed normally and disrupted in disease. ...
By studying a genetic blood disorder, Diamond-Blackfan anemia (DBA), where the majority of mutations affect ribosomal proteins
Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide
Shi Z, et al. Mol Cell 2017. PMID 28625553 Free PMC article.
However, an outstanding question is whether ribosome heterogeneity at the level of core ribosomal proteins (RPs) exists and enables ribosomes to preferentially translate specific mRNAs genome-wide. ...
However, an outstanding question is whether ribosome heterogeneity at the level of core ribosomal proteins (RPs) exists and en …
Ribosomal proteins: insight into molecular roles and functions in hepatocellular carcinoma.
Xie X, et al. Oncogene 2018 - Review. PMID 28945227
Ribosomes, which are important sites for the synthesis of proteins related to expression and transmission of genetic information in humans, have a complex structure and diverse functions. They consist of a variety of ribosomal proteins (RPs), ribosomal RNAs (rRNAs) and small nucleolar RNAs. Owing to the involvement of ribosomes in many important biological processes of cells, their major components, rRNAs and RPs, have an important role in human diseases, including the initiation and evolvement of malignancies. ...
Ribosomes, which are important sites for the synthesis of proteins related to expression and transmission of genetic information in h …
Co-Assembly of 40S and 60S Ribosomal Proteins in Early Steps of Eukaryotic Ribosome Assembly.
Fox JM, et al. Int J Mol Sci 2019. PMID 31181743 Free PMC article.
However, the relative timing of association of ribosomal proteins with the ribosomal precursor particles and the cleavage of the precursor rRNA into the subunit-specific moieties is not known. To address this question, we searched for ribosomal precursors containing components from both subunits. Particles containing specific ribosomal proteins were targeted by inducing synthesis of epitope-tagged ribosomal proteins followed by pull-down with antibodies targeting the tagged protein. ...
However, the relative timing of association of ribosomal proteins with the ribosomal precursor particles and the cleava …
The Discovery of Ribosome Heterogeneity and Its Implications for Gene Regulation and Organismal Life
Genuth NR and Barna M. Mol Cell 2018 - Review. PMID 30075139 Free PMC article.
The first emerging examples of direct changes in ribosome composition at the RNA and protein level, coupled with an increased awareness of the role individual ribosomal components play in the translation of specific mRNAs, is opening a new field of study centered on ribosome-mediated control of gene regulation. ...
The first emerging examples of direct changes in ribosome composition at the RNA and protein level, coupled with an increased awareness of t …
Targeted profiling of RNA translation reveals mTOR-4EBP1/2-independent translation regulation of mRNAs encoding ribosomal proteins.
Li BB, et al. Proc Natl Acad Sci U S A 2018. PMID 30224479 Free PMC article.
Pharmacological inhibition of this pathway preferentially and coordinately suppresses, in a 4EBP1/2-dependent manner, translation of mRNAs encoding ribosomal proteins. ...Together, we describe a translation assay that is directly applicable to large-scale RNA translation studies, and that enabled us to identify a noncanonical, mTOR-independent mode for translation regulation of ribosomal proteins....
Pharmacological inhibition of this pathway preferentially and coordinately suppresses, in a 4EBP1/2-dependent manner, translation of mRNAs e …
12,640 results
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