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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1972 5
1973 16
1974 18
1975 16
1976 21
1977 22
1978 29
1979 17
1980 22
1981 34
1982 47
1983 72
1984 115
1985 155
1986 201
1987 183
1988 216
1989 231
1990 272
1991 247
1992 235
1993 239
1994 247
1995 240
1996 254
1997 327
1998 321
1999 334
2000 381
2001 402
2002 341
2003 401
2004 420
2005 473
2006 449
2007 526
2008 518
2009 572
2010 581
2011 594
2012 597
2013 506
2014 380
2015 322
2016 240
2017 192
2018 179
2019 102
2020 2
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11,529 results
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Page 1
S100 Proteins in Acute Myeloid Leukemia.
Brenner AK and Bruserud Ø. Neoplasia 2018 - Review. PMID 30366122 Free PMC article.
Like in other cancers, it appears as if S100 proteins are potential biomarkers for leukemogenesis. Furthermore, several S100 members seem to be involved in maintaining the leukemic phenotype. For these reasons, specific S100 proteins might serve as prognostic biomarkers, especially in the patient subset with intermediate/undetermined risk, and as potential targets for patient-adjusted therapy. ...
Like in other cancers, it appears as if S100 proteins are potential biomarkers for leukemogenesis. Furthermore, several S10
S100 proteins in rheumatic diseases.
Austermann J, et al. Nat Rev Rheumatol 2018 - Review. PMID 30076385
A growing body of evidence supports a pivotal role for the pro-inflammatory calcium-binding S100 family of proteins in the pathogenesis of rheumatic diseases. ...Some S100 proteins are also valid biomarkers for predicting response to treatment, systemic organ involvement or disease flares in rheumatic diseases. ...
A growing body of evidence supports a pivotal role for the pro-inflammatory calcium-binding S100 family of proteins in the pat …
S100 proteins: An emerging cynosure in pregnancy & adverse reproductive outcome.
Verma R, et al. Indian J Med Res 2018 - Review. PMID 30964086 Free PMC article.
S100 proteins are calcium (Ca(2+))-binding proteins and these have an important function in progression, manifestation and therapeutic aspects of various inflammatory, metabolic and neurodegenerative disorders. ...S100 proteins are expressed particularly in vertebrates and have cell-specific expression. Functionally, S100 proteins act through their surface receptors and regulate cell functions in autocrine or paracrine mode. ...
S100 proteins are calcium (Ca(2+))-binding proteins and these have an important function in progression, manifestation
S100 Proteins in the Innate Immune Response to Pathogens.
Kozlyuk N, et al. Methods Mol Biol 2019. PMID 30710280 Free PMC article.
S100 proteins are distinct dimeric EF-hand Ca(2+)-binding proteins that can bind Zn(2+), Mn(2+), and other transition metals with high affinity at two sites in the dimer interface. Certain S100 proteins, including S100A7, S100A12, S100A8, and S100A9, play key roles in the innate immune response to pathogens. ...
S100 proteins are distinct dimeric EF-hand Ca(2+)-binding proteins that can bind Zn(2+), Mn(2+), and other transition m
S100 proteins in oral squamous cell carcinoma.
Raffat MA, et al. Clin Chim Acta 2018 - Review. PMID 29453969
The aim of the present study was to systematically review the expression of S100 protein family members among OSCC and healthy controls and to evaluate whether S100 protein members serve as diagnostic marker in OSCC. ...With the findings of the present systematic review, the threshold for diagnostic levels of S100 proteins cannot be proposed. ...
The aim of the present study was to systematically review the expression of S100 protein family members among OSCC and healthy contro …
Urine S100 proteins as potential biomarkers of lupus nephritis activity.
Turnier JL, et al. Arthritis Res Ther 2017. PMID 29065913 Free PMC article.
METHODS: In this multicenter study, S100 proteins were measured in the serum and urine of four cSLE cohorts and healthy control subjects using commercial enzyme-linked immunosorbent assays. ...RESULTS: All urine S100 proteins were elevated in patients with active LN compared with patients with active extrarenal disease and healthy control subjects. ...
METHODS: In this multicenter study, S100 proteins were measured in the serum and urine of four cSLE cohorts and healthy contro …
HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins.
Bertheloot D and Latz E. Cell Mol Immunol 2017 - Review. PMID 27569562 Free PMC article.
However, a group of proteins referred to as alarmins have both intracellular and extracellular functions which have been the subject of intense research. ...This group of proteins includes the high-mobility group box 1 protein (HMGB1), interleukin (IL)-1α, IL-33 and the Ca(2+)-binding S100 proteins. ...
However, a group of proteins referred to as alarmins have both intracellular and extracellular functions which have been the subject …
S100 proteins: Diagnostic and prognostic biomarkers in laboratory medicine.
Heizmann CW. Biochim Biophys Acta Mol Cell Res 2019 - Review. PMID 30392897
S100 proteins are members of the superfamily of Ca(2+)-binding proteins characterized by the specific Ca(2+)-binding motif, the EF-hand. ...S100 proteins, the largest sub-group within the EF-hand protein family, are closely associated with cardiovascular diseases, various types of cancer, inflammation and autoimmune pathologies and brain diseases. ...
S100 proteins are members of the superfamily of Ca(2+)-binding proteins characterized by the specific Ca(2+)-binding mo
Serum S100 Proteins as a Marker of Disease Activity in Large Vessel Vasculitis.
Springer JM, et al. J Clin Rheumatol 2018 - Clinical Trial. PMID 29470262 Free PMC article.
This study aimed to determine if levels of serum S100 proteins perform as markers in a comparable fashion to standard markers of disease activity in large-vessel vasculitis. ...A mixed effects model compared S100 proteins during active and inactive disease states. Receiver operating characteristic curves compared models using S100 proteins to models using ESR and CRP. ...
This study aimed to determine if levels of serum S100 proteins perform as markers in a comparable fashion to standard markers …
Binding of transition metals to S100 proteins.
Gilston BA, et al. Sci China Life Sci 2016 - Review. PMID 27430886 Free PMC article.
The S100 proteins are a unique class of EF-hand Ca(2+) binding proteins distributed in a cell-specific, tissue-specific, and cell cycle-specific manner in humans and other vertebrates. ...Here we summarize current knowledge of S100 protein binding of Zn(2+), Cu(2+) and Mn(2+) ions, focusing on binding affinities, conformational changes that arise from metal binding, and the roles of transition metal binding in S100 protein function....
The S100 proteins are a unique class of EF-hand Ca(2+) binding proteins distributed in a cell-specific, tissue-specific …
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