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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 37
1982 32
1983 34
1984 34
1985 40
1986 37
1987 39
1988 38
1989 35
1990 39
1991 38
1992 45
1993 38
1994 36
1995 31
1996 41
1997 32
1998 38
1999 50
2000 49
2001 43
2002 42
2003 44
2004 61
2005 47
2006 40
2007 38
2008 43
2009 42
2010 40
2011 39
2012 42
2013 46
2014 48
2015 45
2016 43
2017 36
2018 41
2019 63
2020 13
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1,604 results
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Page 1
Regression of Liver Fibrosis.
Campana L and Iredale JP. Semin Liver Dis 2017 - Review. PMID 28201843
Liver fibrosis is the final common pathway of chronic or iterative liver damage. Advanced chronic fibrosis is described as cirrhosis with a loss of architecture and attendant functional failure and the development of life-threatening complications. ...Liver disease is a major unmet medical need; currently, the sole approaches are the withdrawal of the injurious stimulus and liver transplantation. ...
Liver fibrosis is the final common pathway of chronic or iterative liver damage. Advanced chronic fibrosis is described as cir
Overview of microRNA biology
Mohr AM and Mott JL. Semin Liver Dis 2015 - Review. PMID 25632930 Free PMC article.
Inflammasomes in Liver Fibrosis.
Alegre F, et al. Semin Liver Dis 2017 - Review. PMID 28564720
Cell death and inflammation are two central elements in the development of liver fibrosis. Inflammasomes are intracellular multiprotein complexes expressed in both hepatocytes and nonparenchymal cells in the liver that are key regulators of inflammation and cell fate. ...From the various inflammasomes, the NLRP3 inflammasome has been increasingly implicated in the pathogenesis of chronic inflammatory liver diseases, including nonalcoholic steatohepatitis, a disease process that is soaring and has evolved as a primary cause of liver fibrosis and need for liver transplantation. ...
Cell death and inflammation are two central elements in the development of liver fibrosis. Inflammasomes are intracellular multiprote …
Acute-on-Chronic Liver Failure: Definition, Diagnosis, and Clinical Characteristics.
Arroyo V and Jalan R. Semin Liver Dis 2016 - Review. PMID 27172351
Organ failure(s) is defined by the Chronic Liver Failure-Sequential Organ Failure (CLIF-SOFA) score or by its simplified version Chronic Liver Failure-Organ Failure Assessment (CLIF-OF) score. ...Acute-on-chronic liver failure may develop at any phase during the clinical course of the disease. Patients without prior AD develop a severe form of ACLF....
Organ failure(s) is defined by the Chronic Liver Failure-Sequential Organ Failure (CLIF-SOFA) score or by its simplified version Chro …
Role of TGR5 (GPBAR1) in Liver Disease.
Keitel V and Häussinger D. Semin Liver Dis 2018 - Review. PMID 30357770
Absence of TGR5 renders mice more susceptible toward infectious, inflammatory, metabolic as well as cholestatic liver injuries. ...While TGR5 agonists may improve various aspects of metabolic, inflammatory, and cholestatic liver diseases, TGR5 inhibitors may attenuate disease progression in polycystic liver disease and cholangiocarcinoma....
Absence of TGR5 renders mice more susceptible toward infectious, inflammatory, metabolic as well as cholestatic liver injuries. ...Wh …
Modified RECIST (mRECIST) assessment for hepatocellular carcinoma
Lencioni R and Llovet JM. Semin Liver Dis 2010 - Review. PMID 20175033
The World Health Organization (WHO) criteria underestimate the actual response rate; thus, they were amended in 2000 by a panel of experts convened by the European Association for the Study of the Liver (EASL) to take into account treatment-induced tumor necrosis. ...In 2008, a group of experts convened by the American Association for the Study of Liver Diseases (AASLD) developed a set of guidelines aimed at providing a common framework for the design of clinical trials in HCC and adapted the concept of viable tumor-tumoral tissue showing uptake in arterial phase of contrast-enhanced radiologic imaging techniques-to formally amend RECIST. ...
The World Health Organization (WHO) criteria underestimate the actual response rate; thus, they were amended in 2000 by a panel of experts c …
Liver Sinusoidal Endothelial Cell: An Update.
DeLeve LD and Maretti-Mira AC. Semin Liver Dis 2017 - Review. PMID 29272898 Free PMC article.
First, recent developments in our understanding of liver sinusoidal endothelial cell (LSEC) function will be reviewed, specifically elimination of blood-borne waste, immunological function of LSECs, interaction of LSECs with liver metastases, LSECs and liver regeneration, and LSECs and hepatic fibrosis. ...
First, recent developments in our understanding of liver sinusoidal endothelial cell (LSEC) function will be reviewed, specifically e …
Liver fibrosis in alcoholic liver disease.
Bataller R and Gao B. Semin Liver Dis 2015 - Review. PMID 25974900
Excessive alcohol consumption causes a wide spectrum of liver disease, ranging from simple steatosis to severe forms of liver injury such as steatohepatitis, liver fibrosis, cirrhosis, and liver cancer. Moreover, alcohol consumption also accelerates liver fibrosis in patients with other types of liver diseases such as viral hepatitis and nonalcoholic fatty liver disease. ...
Excessive alcohol consumption causes a wide spectrum of liver disease, ranging from simple steatosis to severe forms of liver
Update on the Mechanisms of Liver Regeneration.
Preziosi ME and Monga SP. Semin Liver Dis 2017 - Review. PMID 28564722 Free PMC article.
That may be why liver is uniquely bestowed with a capacity to regenerate. A commonly studied procedure to understand the cellular and molecular basis of liver regeneration is that of surgical resection. ...This review highlights recent discoveries in the cellular and molecular basis of liver regeneration....
That may be why liver is uniquely bestowed with a capacity to regenerate. A commonly studied procedure to understand the cellular and …
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