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Characterization of photosensitivity in the Smith-Lemli-Opitz syndrome: a new congenital photosensitivity syndrome.
Anstey AV, Ryan A, Rhodes LE, Charman CR, Arlett CF, Tyrrell RM, Taylor CR, Pearse AD. Anstey AV, et al. Br J Dermatol. 1999 Sep;141(3):406-14. doi: 10.1046/j.1365-2133.1999.03032.x. Br J Dermatol. 1999. PMID: 10583043 Review.
The aim of this study was to establish the photobiological features of this disorder and to examine the hypothesis that the photosensitivity is caused by the high levels of 7-dehydrocholesterol found in SLO. All known cases of SLO in the U.K. were reviewed and clinical det …
The aim of this study was to establish the photobiological features of this disorder and to examine the hypothesis that the photosensitivity …
Vemurafenib and ipilimumab: new agents for metastatic melanoma.
Banaszynski M, Kolesar JM. Banaszynski M, et al. Am J Health Syst Pharm. 2013 Jul 15;70(14):1205-10. doi: 10.2146/ajhp120260. Am J Health Syst Pharm. 2013. PMID: 23820456 Review.
Disadvantages of vemurafenib include the short duration of response; significant skin toxicities, including skin cancers and severe photosensitivity; the need for long-term daily administration; and the potential for drug interactions. ...Benefit is typically short …
Disadvantages of vemurafenib include the short duration of response; significant skin toxicities, including skin cancers and severe …
Pirfenidone in idiopathic pulmonary fibrosis: real-life experience in the referral centre of Siena.
Vietri L, Cameli P, Perruzza M, Cekorja B, Bergantini L, d'Alessandro M, Refini RM, Pieroni M, Fossi A, Bennett D, Spalletti M, Mazzei MA, Sestini P, Rottoli P, Bargagli E. Vietri L, et al. Ther Adv Respir Dis. 2020 Jan-Dec;14:1753466620906326. doi: 10.1177/1753466620906326. Ther Adv Respir Dis. 2020. PMID: 32066332 Free PMC article.
METHODS: We enrolled 91 patients with IPF (71 males) treated with pirfenidone. Clinical, survival and functional details were collected retrospectively at start of therapy and after 12, 24, 36 and 48 months of treatment. ...Treatment-related side effects were reported in 2 …
METHODS: We enrolled 91 patients with IPF (71 males) treated with pirfenidone. Clinical, survival and functional details were collect …
The use of vemurafenib in Australian patients with unresectable or metastatic melanoma containing the V600 BRAF gene mutation.
Brown MP, Long GV. Brown MP, et al. Asia Pac J Clin Oncol. 2014 Apr;10 Suppl S3:1-15. doi: 10.1111/ajco.12200. Asia Pac J Clin Oncol. 2014. PMID: 24712861 Review.
Metastatic melanoma remains one of the major causes of death related to skin cancers and has been resistant to traditional anticancer therapies. The clinical development of vemurafenib in the treatment of metastatic melanoma with the V600 mutation of the BRAF gene has prov …
Metastatic melanoma remains one of the major causes of death related to skin cancers and has been resistant to traditional anticancer therap …
Novel Treatment Using Cimetidine for Erythropoietic Protoporphyria in Children.
Tu JH, Sheu SL, Teng JM. Tu JH, et al. JAMA Dermatol. 2016 Nov 1;152(11):1258-1261. doi: 10.1001/jamadermatol.2016.2303. JAMA Dermatol. 2016. PMID: 27410690
IMPORTANCE: Erythropoietic protoporphyria (EPP) is a rare hereditary disease of heme biosynthesis that manifests as severe photosensitivity and hepatotoxicity. There have been no effective treatments to date. ...MAIN OUTCOMES AND MEASURES: Resolution of skin photoda …
IMPORTANCE: Erythropoietic protoporphyria (EPP) is a rare hereditary disease of heme biosynthesis that manifests as severe photose …
Erythroid-Progenitor-Targeted Gene Therapy Using Bifunctional TFR1 Ligand-Peptides in Human Erythropoietic Protoporphyria.
Mirmiran A, Schmitt C, Lefebvre T, Manceau H, Daher R, Oustric V, Poli A, Lacapère JJ, Moulouel B, Puy H, Karim Z, Peoc'h K, Lenglet H, Simonin S, Deybach JC, Nicolas G, Gouya L. Mirmiran A, et al. Am J Hum Genet. 2019 Feb 7;104(2):341-347. doi: 10.1016/j.ajhg.2018.12.021. Epub 2019 Jan 31. Am J Hum Genet. 2019. PMID: 30712775 Free PMC article.
FECH activity is responsible for the accumulation of protoporphyrin IX (PPIX). Without etiopathogenic treatment, EPP manifests as severe photosensitivity. 95% of affected individuals present a hypomorphic FECH allele trans to a loss-of-function (LOF) FECH mutation, …
FECH activity is responsible for the accumulation of protoporphyrin IX (PPIX). Without etiopathogenic treatment, EPP manifests as severe …
The impact of photosensitivity disorders on aspects of lifestyle.
Stafford R, Farrar MD, Kift R, Durkin MT, Berry JL, Webb AR, Rhodes LE. Stafford R, et al. Br J Dermatol. 2010 Oct;163(4):817-22. doi: 10.1111/j.1365-2133.2010.09905.x. Epub 2010 Sep 10. Br J Dermatol. 2010. PMID: 20545692
METHODS: Questionnaires were completed by ambulant photosensitive and healthy adults aged 18-60 years residing in Greater Manchester. RESULTS: Forty-five adults with moderate-severe photosensitivity and 124 healthy adults completed the questionnaire. ...
METHODS: Questionnaires were completed by ambulant photosensitive and healthy adults aged 18-60 years residing in Greater Manchester. RESULT …
Radiation-induced dermatitis after administration of mogamulizumab for adult T-cell leukaemia/lymphoma: a multi-institutional retrospective study.
Maemoto H, Ariga T, Kusada T, Heianna J, Manabe Y, Miyakawa A, Nakachi S, Morishima S, Iraha S, Ganaha F, Masuzaki H, Murayama S. Maemoto H, et al. Jpn J Clin Oncol. 2019 Feb 1;49(2):153-159. doi: 10.1093/jjco/hyy172. Jpn J Clin Oncol. 2019. PMID: 30452692
Cases of Stevens-Johnson syndrome, toxic epidermal necrolysis and severe photosensitivity related to mogamulizumab have been reported. ...
Cases of Stevens-Johnson syndrome, toxic epidermal necrolysis and severe photosensitivity related to mogamulizumab have been r …
Ongoing Photosensitivity in An Elderly Patient With Jeavons Sydrome.
Gülen Abanoz Y, Abanoz Y, Özkara Ç. Gülen Abanoz Y, et al. Neurologist. 2018 May;23(3):94-97. doi: 10.1097/NRL.0000000000000175. Neurologist. 2018. PMID: 29722743
CASE REPORT: We describe a 63-year-old male patient with eyelid myoclonia with absences, generalized tonic-clonic seizures, and severe photosensitivity accompanied by eyelid myoclonia. Seizures were treated with antiepileptic treatment, whereas photosensitivity stil …
CASE REPORT: We describe a 63-year-old male patient with eyelid myoclonia with absences, generalized tonic-clonic seizures, and severe …
Severe photosensitivity reaction to vandetanib.
Chang CH, Chang JW, Hui CY, Yang CH. Chang CH, et al. J Clin Oncol. 2009 Sep 20;27(27):e114-5. doi: 10.1200/JCO.2009.21.8479. Epub 2009 Jun 29. J Clin Oncol. 2009. PMID: 19564539 No abstract available.
34 results