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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1991 6
1992 23
1993 33
1994 37
1995 59
1996 61
1997 58
1998 74
1999 59
2000 67
2001 58
2002 38
2003 42
2004 40
2005 40
2006 42
2007 37
2008 47
2009 47
2010 49
2011 49
2012 51
2013 35
2014 39
2015 40
2016 32
2017 25
2018 18
2019 11
2020 0
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1,139 results
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Page 1
Natural RNA circles function as efficient microRNA sponges
Hansen TB, et al. Nature 2013. PMID 23446346
We further show that the testis-specific circRNA, sex-determining region Y (Sry), serves as a miR-138 sponge, suggesting that miRNA sponge effects achieved by circRNA formation are a general phenomenon. ...
We further show that the testis-specific circRNA, sex-determining region Y (Sry), serves as a miR-138 sponge, su …
Bovine Sex Determining Region Y: Cloning, Optimized Expression, and Purification.
Soleymani B, et al. Anim Biotechnol 2017. PMID 27715460
Sex determining region Y gene (SRY) is located on Y chromosome and encodes a protein with 229 amino acids. In this study, ORF region of SRY with a length of 690 bp was synthesized using PCR and ligated to pET28a (+), then transformed in E.coli DH5α. ...Results showed that temperature points and different concentrations of IPTG and glucose had a significant effect (p < 0.01) on total protein and recombinant bovine SRY. ...
Sex determining region Y gene (SRY) is located on Y chromosome and encodes a protein with 229 amin
Sex reversal following deletion of a single distal enhancer of Sox9.
Gonen N, et al. Science 2018. PMID 29903884 Free PMC article.
Sox9, a direct target of SRY, is pivotal in mammalian sex determination. In vivo high-throughput chromatin accessibility techniques, transgenic assays, and genome editing revealed several novel gonadal regulatory elements in the 2-megabase gene desert upstream of Sox9 Although others are redundant, enhancer 13 (Enh13), a 557-base pair element located 565 kilobases 5' from the transcriptional start site, is essential to initiate mouse testis development; its deletion results in XY females with Sox9 transcript levels equivalent to those in XX gonads. ...Enh13 is conserved and embedded within a 32.5-kilobase region whose deletion in humans is associated with XY sex reversal, suggesting that it is also critical in humans....
Sox9, a direct target of SRY, is pivotal in mammalian sex determination. In vivo high-throughput chromatin accessibility techniques, …
Label-free detection of sex determining region Y (SRY) via capacitive biosensor.
Sivashankar S, et al. Conf Proc IEEE Eng Med Biol Soc 2016. PMID 28269241
In this work, we present for the first time, the use of a simple fractal capacitive biosensor for the quantification and detection of sex-determining region Y (SRY) genes. This section of genetic code, which is found on the Y chromosome, finds importance for study as it causes fetuses to develop characteristics of male sex-like gonads when a mutation occurs. ...
In this work, we present for the first time, the use of a simple fractal capacitive biosensor for the quantification and detection of sex
Sry and SoxE genes: How they participate in mammalian sex determination and gonadal development?
She ZY and Yang WX. Semin Cell Dev Biol 2017 - Review. PMID 27481580
In mammals, sex determination defines the differentiation of the bipotential genital ridge into either testes or ovaries. Sry, the mammalian Y-chromosomal testis-determining gene, is a master regulator of male sex determination. ...The mutual antagonisms between male and female sex-determining pathways are crucial in not just the initiation but also the maintenance of the somatic sex of the gonad throughout the organism's lifetime. ...
In mammals, sex determination defines the differentiation of the bipotential genital ridge into either testes or ovaries. Sry, the ma …
A novel sex-determining region on Y (SRY) missense mutation identified in a 46,XY female and also in the father.
Imai A, et al. Endocr J 1999. PMID 10670762 Free article.
Mutations in the sex-determining gene SR Y previously identified occur in the 46, XY females. In this study, we investigated whether the SR Y mutation participates in the onset of XY sex reversal. ...One of the 46, XY females suffered a novel missense mutation at position 306 of SR Y gene, wherein cytosine was replaced by adenine (CGC-->AGC), resulting in a substitution of serine for arginine at amino acid position 76 of SR Y protein. ...
Mutations in the sex-determining gene SR Y previously identified occur in the 46, XY females. In this study, we investi …
Identification of sex-determining region Y (SRY) in maternal plasma after paternal lymphocyte immunization: is it possible?
Machado IN, et al. Am J Reprod Immunol 2012. PMID 22032865
This study evaluated the applicability of fetal sex determination using fragments of sex-determining region Y (SRY) in the plasma of women submitted to paternal lymphocyte immunization. ...For the 26 pregnant women, the results of the identification of sex -determining in maternal plasma were completely in agreement with the infant sex. ...
This study evaluated the applicability of fetal sex determination using fragments of sex-determining region Y
Regulation of CATSPER1 expression by the testis-determining gene SRY.
Olivares A, et al. PLoS One 2018. PMID 30379860 Free PMC article.
CATSPER1 gene encodes a pore-forming and pH-sensing subunit of the CatSper Ca2+- permeable channel, a protein in the flagellum essential for sperm hyperactivation. ...Likewise, it is acknowledged that the human CATSPER1 gene promoter sequence is enriched in potential interaction sites for the sex-determining region Y gene (SRY), which suggest a novel regulatory transcriptional mechanism for CatSper1 channel expression. ...
CATSPER1 gene encodes a pore-forming and pH-sensing subunit of the CatSper Ca2+- permeable channel, a protein in the flagellum essent …
Localization of the SRY Gene on Chromosome 3 in a Patient with Azoospermia and a Complex Karyotype 45,X/46,X,i(Y)(q10)/46,XX/ 47,XX,i(Y)(q10).
Barnabas LC, et al. Cytogenet Genome Res 2018. PMID 30466086
Cytogenetic evaluation was performed by G-banding, C-banding, and FISH using centromeric probes for chromosomes X and Y and showed the presence of a monocentric isochromosome Y with a complex, mosaic karyotype 45,X/46,X,i(Y)(q10)/46,XX/47,XX,i(Y)(q10). ...Subtelomere FISH for 3q and Yp evidenced that the subtelomeric region of the Y chromosome was found on the terminal region of 3q. ...
Cytogenetic evaluation was performed by G-banding, C-banding, and FISH using centromeric probes for chromosomes X and Y and showed th …
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