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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 2
1967 5
1968 12
1969 11
1970 14
1971 13
1972 10
1973 15
1974 16
1975 8
1976 18
1977 11
1978 10
1979 14
1980 17
1981 60
1982 50
1983 56
1984 34
1985 45
1986 31
1987 26
1988 24
1989 25
1990 38
1991 35
1992 38
1993 53
1994 31
1995 32
1996 44
1997 35
1998 36
1999 58
2000 56
2001 48
2002 44
2003 71
2004 79
2005 60
2006 62
2007 68
2008 82
2009 76
2010 102
2011 99
2012 121
2013 115
2014 134
2015 137
2016 130
2017 119
2018 119
2019 70
2020 1
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2,589 results
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Page 1
Septic Shock: Advances in Diagnosis and Treatment.
Seymour CW and Rosengart MR. JAMA 2015 - Review. PMID 26284722 Free PMC article.
IMPORTANCE: Septic shock is a clinical emergency that occurs in more than 230,000 US patients each year. OBSERVATIONS AND ADVANCES: In the setting of suspected or documented infection, septic shock is typically defined in a clinical setting by low systolic (≤90 mm Hg) or mean arterial blood pressure (≤65 mm Hg) accompanied by signs of hypoperfusion (eg, oliguria, hyperlactemia, poor peripheral perfusion, or altered mental status). ...In septic shock, 3 randomized clinical trials demonstrate that protocolized care offers little advantage compared with management without a protocol. ...
IMPORTANCE: Septic shock is a clinical emergency that occurs in more than 230,000 US patients each year. OBSERVATIONS AND ADVA …
The recognition and management of sepsis and septic shock: a guide for non-intensivists.
Keeley A, et al. Postgrad Med J 2017 - Review. PMID 28756405
Sepsis is common, often fatal and requires rapid interventions to improve outcomes. While the optimal management of sepsis in the intensive care setting is the focus of extensive research interest, the mainstay of the recognition and initial management of sepsis will occur outside the intensive care setting. ...This review discusses the latest updates in sepsis care including the new consensus definition of sepsis, the outcome of the proCESS, ProMISe and ARISE trials of early goal directed therapy (EGDT), and the most recent guidelines from the Surviving Sepsis Campaign....
Sepsis is common, often fatal and requires rapid interventions to improve outcomes. While the optimal management of sepsis in
Advances in the Management of Pediatric Septic Shock: Old Questions, New Answers.
Ismail J and Jayashree M. Indian Pediatr 2018 - Review. PMID 29726824 Free article.
It is therefore imperative for all of us to be aware of the recent changes in management, to enable us to adopt an evidenced based approach while managing children with septic shock. In this review, we have tried to summarize the key changes in evidence that have occurred over the past decade at various steps in the management of pediatric septic shock....
It is therefore imperative for all of us to be aware of the recent changes in management, to enable us to adopt an evidenced based approach …
Role of Point-of-Care Ultrasonography for the Management of Sepsis and Septic Shock.
Shrestha GS and Srinivasan S. Rev Recent Clin Trials 2018 - Review. PMID 29651944
BACKGROUND: Sepsis and septic shock remain a major cause of morbidity and mortality globally. In recent years, the outcome of patients with sepsis and septic shock has gradually improved, in part due to early recognition and timely appropriate management. ...CONCLUSION: Bedside ultrasound can help to individualize management of patients with sepsis and septic shock and may potentially improve patient outcome....
BACKGROUND: Sepsis and septic shock remain a major cause of morbidity and mortality globally. In recent years, the outc …
New Sepsis and Septic Shock Definitions: Clinical Implications and Controversies.
Rhee C and Klompas M. Infect Dis Clin North Am 2017 - Review. PMID 28687209
The diagnosis of septic shock requires vasopressor dependence and increased lactate levels. Strengths of these definitions include their simplicity and clear association with adverse outcomes. However, their utility in identifying patients with serious infections before frank sepsis ensues remains to be seen. This article reviews challenges in defining sepsis, strengths and weaknesses of the new definitions, and unresolved issues....
The diagnosis of septic shock requires vasopressor dependence and increased lactate levels. Strengths of these definitions inc …
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock.
Dellinger RP, et al. Crit Care Med 2004 - Review. PMID 15090974
OBJECTIVE: In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines for severe sepsis and septic shock that would be of practical use for the bedside clinician, under the auspices of the Surviving Sepsis Campaign, an international effort to increase awareness and improve outcome in severe sepsis. ...CONCLUSION: Evidence-based recommendations can be made regarding many aspects of the acute management of sepsis and septic shock that are hoped to translate into improved outcomes for the critically ill patient. ...
OBJECTIVE: In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines …
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012.
Dellinger RP, et al. Intensive Care Med 2013. PMID 23361625
OBJECTIVE: To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. ...Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for this important group of critically ill patients....
OBJECTIVE: To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic
A targeted real-time early warning score (TREWScore) for septic shock.
Henry KE, et al. Sci Transl Med 2015. PMID 26246167
Sepsis is a leading cause of death in the United States, with mortality highest among patients who develop septic shock. Early aggressive treatment decreases morbidity and mortality. Although automated screening tools can detect patients currently experiencing severe sepsis and septic shock, none predict those at greatest risk of developing shock. ...
Sepsis is a leading cause of death in the United States, with mortality highest among patients who develop septic shock
Defining Septic Shock--Reply.
Shankar-Hari M and Singer M. JAMA 2016. PMID 27458958
Defining Septic Shock.
Hernández G, et al. JAMA 2016. PMID 27458954
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