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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2005 6
2006 17
2007 16
2008 15
2009 18
2010 20
2011 24
2012 11
2013 17
2014 10
2015 17
2016 16
2017 8
2018 14
2019 8
2020 16
2021 12
2022 5
2023 6
2024 0

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225 results

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Page 1
Siglecs and their roles in the immune system.
Crocker PR, Paulson JC, Varki A. Crocker PR, et al. Nat Rev Immunol. 2007 Apr;7(4):255-66. doi: 10.1038/nri2056. Nat Rev Immunol. 2007. PMID: 17380156 Review.
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains.
Pluvinage JV, Haney MS, Smith BAH, Sun J, Iram T, Bonanno L, Li L, Lee DP, Morgens DW, Yang AC, Shuken SR, Gate D, Scott M, Khatri P, Luo J, Bertozzi CR, Bassik MC, Wyss-Coray T. Pluvinage JV, et al. Nature. 2019 Apr;568(7751):187-192. doi: 10.1038/s41586-019-1088-4. Epub 2019 Apr 3. Nature. 2019. PMID: 30944478 Free PMC article.
Impact of Siglecs on autoimmune diseases.
Brzezicka KA, Paulson JC. Brzezicka KA, et al. Mol Aspects Med. 2023 Apr;90:101140. doi: 10.1016/j.mam.2022.101140. Epub 2022 Aug 30. Mol Aspects Med. 2023. PMID: 36055802 Free PMC article. Review.
Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells.
Singh N, Frey NV, Engels B, Barrett DM, Shestova O, Ravikumar P, Cummins KD, Lee YG, Pajarillo R, Chun I, Shyu A, Highfill SL, Price A, Zhao L, Peng L, Granda B, Ramones M, Lu XM, Christian DA, Perazzelli J, Lacey SF, Roy NH, Burkhardt JK, Colomb F, Damra M, Abdel-Mohsen M, Liu T, Liu D, Standley DM, Young RM, Brogdon JL, Grupp SA, June CH, Maude SL, Gill S, Ruella M. Singh N, et al. Nat Med. 2021 May;27(5):842-850. doi: 10.1038/s41591-021-01326-5. Epub 2021 Apr 22. Nat Med. 2021. PMID: 33888899 Free PMC article. Clinical Trial.
Sialic acids and autoimmune disease.
Mahajan VS, Pillai S. Mahajan VS, et al. Immunol Rev. 2016 Jan;269(1):145-61. doi: 10.1111/imr.12344. Immunol Rev. 2016. PMID: 26683151 Free PMC article. Review.
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C.
Pluvinage JV, Sun J, Claes C, Flynn RA, Haney MS, Iram T, Meng X, Lindemann R, Riley NM, Danhash E, Chadarevian JP, Tapp E, Gate D, Kondapavulur S, Cobos I, Chetty S, Pașca AM, Pașca SP, Berry-Kravis E, Bertozzi CR, Blurton-Jones M, Wyss-Coray T. Pluvinage JV, et al. Sci Transl Med. 2021 Dec;13(622):eabg2919. doi: 10.1126/scitranslmed.abg2919. Epub 2021 Dec 1. Sci Transl Med. 2021. PMID: 34851695 Free PMC article.
Prosthetic Antigen Receptors.
Shen J, Vallera DA, Wagner CR. Shen J, et al. J Am Chem Soc. 2015 Aug 19;137(32):10108-11. doi: 10.1021/jacs.5b06166. Epub 2015 Aug 6. J Am Chem Soc. 2015. PMID: 26230248
225 results