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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 2
1947 6
1948 23
1949 9
1950 9
1951 6
1952 9
1953 2
1954 2
1955 6
1956 6
1957 7
1958 6
1959 9
1960 5
1961 9
1962 5
1963 15
1964 17
1965 6
1966 1
1968 1
1973 4
1975 3
1976 2
1977 1
1978 1
1979 5
1980 27
1981 51
1982 87
1983 105
1984 159
1985 133
1986 142
1987 116
1988 105
1989 124
1990 126
1991 100
1992 114
1993 108
1994 91
1995 98
1996 99
1997 106
1998 94
1999 99
2000 84
2001 94
2002 91
2003 82
2004 109
2005 117
2006 125
2007 135
2008 132
2009 126
2010 159
2011 160
2012 162
2013 181
2014 153
2015 154
2016 152
2017 127
2018 148
2019 82
2020 1
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4,564 results
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Page 1
Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial.
Jaber S, et al. Lancet 2018 - Clinical Trial. PMID 29910040 Free article.
Therefore, we aimed to evaluate whether sodium bicarbonate infusion would improve these outcomes in critically ill patients. ...We randomly assigned patients (1:1), by stratified randomisation with minimisation via a restricted web platform, to receive either no sodium bicarbonate (control group) or 4·2% of intravenous sodium bicarbonate infusion (bicarbonate group) to maintain the arterial pH above 7·30. ...
Therefore, we aimed to evaluate whether sodium bicarbonate infusion would improve these outcomes in critically ill patients. . …
Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine.
Weisbord SD, et al. N Engl J Med 2018 - Clinical Trial. PMID 29130810 Free article.
BACKGROUND: Intravenous sodium bicarbonate and oral acetylcysteine are widely used to prevent acute kidney injury and associated adverse outcomes after angiography without definitive evidence of their efficacy. ...There was no interaction between sodium bicarbonate and acetylcysteine with respect to the primary end point (P=0.33). The primary end point occurred in 110 of 2511 patients (4.4%) in the sodium bicarbonate group as compared with 116 of 2482 (4.7%) in the sodium chloride group (odds ratio, 0.93; 95% confidence interval [CI], 0.72 to 1.22; P=0.62) and in 114 of 2495 patients (4.6%) in the acetylcysteine group as compared with 112 of 2498 (4.5%) in the placebo group (odds ratio, 1.02; 95% CI, 0.78 to 1.33; P=0.88). ...
BACKGROUND: Intravenous sodium bicarbonate and oral acetylcysteine are widely used to prevent acute kidney injury and associat …
Sodium bicarbonate: A review and its uses in dentistry.
Madeswaran S and Jayachandran S. Indian J Dent Res 2018 - Review. PMID 30409952 Free article.
Sodium bicarbonate, the common baking soda, has been reported to be versatile. A search of the resources through Medline and Google Scholar was made to understand the current status of the mouth rinses and the use of sodium bicarbonate. ...
Sodium bicarbonate, the common baking soda, has been reported to be versatile. A search of the resources through Medline and G
Uses and misuses of sodium bicarbonate in the neonatal intensive care unit.
Collins A and Sahni R. Semin Fetal Neonatal Med 2017 - Review. PMID 28801177
Clinicians often feel compelled to use bicarbonate since acidosis implies a need for such therapy and thus the justification for its use is based on hearsay rather than science. This review summarizes the evidence and refutes the clinical practice of administering sodium bicarbonate to treat metabolic acidosis associated with several specific clinical syndromes in neonates....
Clinicians often feel compelled to use bicarbonate since acidosis implies a need for such therapy and thus the justification for its …
A Literature Review of the Use of Sodium Bicarbonate for the Treatment of QRS Widening.
Bruccoleri RE and Burns MM. J Med Toxicol 2016 - Review. PMID 26159649 Free PMC article.
Sodium bicarbonate is a well-known antidote for tricyclic antidepressant (TCA) poisoning. It has been used for over half a century to treat toxin-induced sodium channel blockade as evidenced by QRS widening on the electrocardiogram (ECG). ...This article will also address the literature supporting an increased serum sodium concentration, alkalemia, or the combination of both as the responsible mechanism(s) for sodium bicarbonate's antidotal properties. ...
Sodium bicarbonate is a well-known antidote for tricyclic antidepressant (TCA) poisoning. It has been used for over half a cen
"Sodium bicarbonate": an adjunct to painless palatal anesthesia.
Gupta S, et al. Oral Maxillofac Surg 2018 - Clinical Trial. PMID 30324508
The aim of this study was to make palatal anesthesia painless by adding 7.4% sodium bicarbonate as an adjunct in local anesthesia. ...CONCLUSION: Effect of sodium bicarbonate on reducing pain while injecting into the palatal aspect was noted in this study....
The aim of this study was to make palatal anesthesia painless by adding 7.4% sodium bicarbonate as an adjunct in local anesthe …
Effectiveness of sodium bicarbonate infusion on mortality in septic patients with metabolic acidosis.
Zhang Z, et al. Intensive Care Med 2018. PMID 30255318
OBJECTIVE: Although sodium bicarbonate (SB) solution has been widely used in clinical practice, its effect on mortality when administered to a large population of patients with acidosis is not known. ...Both pH [7.16 (standard deviation (SD): 0.10) vs. 7.22 (SD: 0.07); p < 0.001] and bicarbonate concentration (BC) [11.84 (SD: 3.63) vs. 14.88 (SD: 3.36) mmol/l; p < 0.001] were significantly lower in the SB than that in the non-SB group. ...
OBJECTIVE: Although sodium bicarbonate (SB) solution has been widely used in clinical practice, its effect on mortality when a …
Efficacy of omeprazole/sodium bicarbonate treatment in gastroesophageal reflux disease: a systematic review.
Higuera-de-la-Tijera F. Medwave 2018 - Review. PMID 29547594 Spanish, English.
OBJECTIVES: To assess the available literature regarding the efficacy of omeprazole/sodium bicarbonate in gastroesophageal reflux patients. ...And another study compared omeprazole/sodium bicarbonate/alginate versus omeprazole. In total, there was no difference between omeprazole/sodium bicarbonate and omeprazole. ...
OBJECTIVES: To assess the available literature regarding the efficacy of omeprazole/sodium bicarbonate in gastroesophageal ref …
Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated Acute Kidney Injury in Critically Ill Patients: A Randomized Controlled Trial.
Valette X, et al. Crit Care Med 2017 - Clinical Trial. PMID 28181941
INTERVENTIONS: Hydration with 0.9% sodium chloride or 1.4% sodium bicarbonate administered with the same infusion protocol: 3 mL/kg during 1 hour before and 1 mL/kg/hr during 6 hours after contrast medium exposure. ...Among ICU patients with stable renal function, the benefit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associated acute kidney injury is marginal, if any....
INTERVENTIONS: Hydration with 0.9% sodium chloride or 1.4% sodium bicarbonate administered with the same infusion proto …
Sodium Bicarbonate for Control of ICP: A Systematic Review.
Zeiler FA, et al. J Neurosurg Anesthesiol 2018 - Review. PMID 27673506
Twenty-one of those episodes were treated with sodium bicarbonate infusion, with the remaining 10 treated with hypertonic saline in a control model. All elevated ICP episodes treated with sodium bicarbonate solution demonstrated a significant drop in ICP, without an elevation of serum partial pressure of carbon dioxide. ...
Twenty-one of those episodes were treated with sodium bicarbonate infusion, with the remaining 10 treated with hypertonic sali …
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