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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1968 2
1969 2
1970 10
1971 50
1972 43
1973 63
1974 95
1975 78
1976 65
1977 76
1978 106
1979 137
1980 208
1981 183
1982 279
1983 341
1984 431
1985 432
1986 351
1987 336
1988 421
1989 552
1990 521
1991 647
1992 656
1993 736
1994 833
1995 953
1996 1031
1997 1080
1998 1192
1999 1430
2000 1524
2001 1740
2002 2262
2003 2621
2004 2944
2005 3789
2006 4534
2007 5160
2008 5916
2009 6537
2010 7960
2011 8821
2012 9806
2013 10642
2014 9852
2015 10049
2016 9933
2017 10356
2018 9421
2019 3565
2020 34
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126,460 results
Results by year
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Page 1
Cancer stem cells revisited.
Batlle E and Clevers H. Nat Med 2017 - Review. PMID 28985214
The cancer stem cell (CSC) concept was proposed four decades ago, and states that tumor growth, analogous to the renewal of healthy tissues, is fueled by small numbers of dedicated stem cells. ...Here we discuss new developments in the CSC field in relationship to changing insights into how normal stem cells maintain healthy tissues. ...
The cancer stem cell (CSC) concept was proposed four decades ago, and states that tumor growth, analogous to the renewal of healthy t …
DNA Damage in Stem Cells.
Vitale I, et al. Mol Cell 2017 - Review. PMID 28475867 Free article.
Both embryonic and adult stem cells are endowed with a superior capacity to prevent the accumulation of genetic lesions, repair them, or avoid their propagation to daughter cells, which would be particularly detrimental to the whole organism. ...Here, we discuss the pathophysiological and therapeutic implications of the molecular pathways through which stem cells cope with DNA damage....
Both embryonic and adult stem cells are endowed with a superior capacity to prevent the accumulation of genetic lesions, repai …
Influence of pH on Skin Stem Cells and Their Differentiation.
Charruyer A and Ghadially R. Curr Probl Dermatol 2018 - Review. PMID 30130775
Intracellular pH influences proliferation and differentiation in a range of stem-like and progenitor cells, including embryonic stem cells, induced pluripotent stem cells, mesenchymal stem cells, and cancer stem cells. ...Study of the influence of NHE1 and intracellular pH on epidermal stem cell behavior could lead to the discovery of new targets to use in order to manipulate stem cell divisions. ...
Intracellular pH influences proliferation and differentiation in a range of stem-like and progenitor cells, including embryoni …
Deconstructing and reconstructing the mouse and human early embryo
Shahbazi MN and Zernicka-Goetz M. Nat Cell Biol 2018 - Review. PMID 30038253
The foundations of the body plan are laid throughout the first days of post-implantation development as embryonic stem cells undergo symmetry breaking and initiate lineage specification, in a process that coincides with a global morphological reorganization of the embryo. ...
The foundations of the body plan are laid throughout the first days of post-implantation development as embryonic stem cells u …
Stem cells in the treatment of diabetes mellitus - Focus on mesenchymal stem cells.
Päth G, et al. Metabolism 2019 - Review. PMID 30342065
Beside traditional treatment with insulin and oral anti-diabetic drugs, clinicians try to improve patient's care by cell therapies using embryonic stem cells (ESC), induced pluripotent stem cells (iPSC) and adult mesenchymal stem cells (MSC). ESC display a virtually unlimited plasticity, including the differentiation into insulin producing β-cells, but they raise ethical concerns and bear, like iPSC, the risk of tumours. ...
Beside traditional treatment with insulin and oral anti-diabetic drugs, clinicians try to improve patient's care by cell therapies using emb …
Blood stem cells: from beginning to end.
Bigas A and Waskow C. Development 2016 - Review. PMID 27702782 Free article.
In June 2016, around 200 scientists from all over the world gathered at EMBL headquarters in Heidelberg, Germany to discuss the recent advances in hematopoietic stem cells from three different angles: developmental, adulthood and aging. The meeting, aptly named 'Hematopoietic stem cells: from the embryo to the aging organism' also covered cutting-edge technologies applied to this subject, such as single-cell analysis, reprogramming and imaging. ...
In June 2016, around 200 scientists from all over the world gathered at EMBL headquarters in Heidelberg, Germany to discuss the recent advan …
Quiescence Entry, Maintenance, and Exit in Adult Stem Cells.
Mohammad K, et al. Int J Mol Sci 2019 - Review. PMID 31052375 Free PMC article.
Quiescent cells in mammals and humans include adult stem cells. These cells exhibit improved stress resistance and enhanced survival ability. ...In this review, we describe many traits shared by different types of quiescent adult stem cells. We discuss how these traits contribute to the quiescence, self-renewal, and proliferation of adult stem cells. ...
Quiescent cells in mammals and humans include adult stem cells. These cells exhibit improved stress resistance a …
Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells.
Lim WF, et al. Stem Cell Res Ther 2013 - Review. PMID 23796405 Free PMC article.
Pluripotent stem cells, both embryonic stem cells and induced pluripotent stem cells, are undifferentiated cells that can self-renew and potentially differentiate into all hematopoietic lineages, such as hematopoietic stem cells (HSCs), hematopoietic progenitor cells and mature hematopoietic cells in the presence of a suitable culture system. ...We hereby review the current progress of hematopoietic cell induction from embryonic stem/induced pluripotent stem cells....
Pluripotent stem cells, both embryonic stem cells and induced pluripotent stem cells, are undiffer …
126,460 results
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