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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 1
1965 1
1966 4
1967 12
1968 9
1969 17
1970 12
1971 20
1972 7
1973 11
1974 14
1975 10
1976 18
1977 17
1978 16
1979 19
1980 18
1981 31
1982 31
1983 29
1984 39
1985 42
1986 39
1987 43
1988 53
1989 70
1990 62
1991 76
1992 72
1993 87
1994 103
1995 117
1996 102
1997 109
1998 143
1999 135
2000 138
2001 176
2002 203
2003 202
2004 268
2005 287
2006 286
2007 325
2008 360
2009 431
2010 494
2011 557
2012 621
2013 688
2014 754
2015 818
2016 776
2017 778
2018 723
2019 348
2020 4
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9,739 results
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Page 1
Systemic inflammatory response syndrome in Sepsis-3: a retrospective study.
Zhang W, et al. BMC Infect Dis 2019. PMID 30744579 Free PMC article.
BACKGROUND: In the new Sepsis-3 definition, sepsis is defined as "life-threatening organ dysfunction due to a dysregulated host response to infection." We tested the predictive validity of the systematic inflammatory response syndrome (SIRS) criteria in patients in the Sepsis-3 cohort. ...
BACKGROUND: In the new Sepsis-3 definition, sepsis is defined as "life-threatening organ dysfunction due to a dysregulated hos …
Presumed Systemic Inflammatory Response Syndrome in the Pediatric Emergency Department.
Foo CPZ, et al. Pediatr Emerg Care 2019. PMID 29438125
OBJECTIVE: The aim of this study was to examine the incidence and outcomes of patients presenting with systemic inflammatory response syndrome (SIRS) in the pediatric emergency department (PED). ...CONCLUSIONS: Presumed SIRS and sepsis are relatively common in the PED. Use of pSIRS to screen for sepsis risks missing infection, whereas using pSIRS in the current sepsis definition results in overinclusion of nonsevere illness....
OBJECTIVE: The aim of this study was to examine the incidence and outcomes of patients presenting with systemic inflammator
Epidemiology of the Systemic Inflammatory Response Syndrome (SIRS) in the emergency department.
Horeczko T, et al. West J Emerg Med 2014. PMID 24868313 Free PMC article.
INTRODUCTION: Consensus guidelines recommend sepsis screening for adults with systemic inflammatory response syndrome (SIRS), but the epidemiology of SIRS among adult emergency department (ED) patients is poorly understood. ...CONCLUSION: SIRS is very common in the ED. Infectious etiologies make up only a quarter of adult SIRS cases. SIRS may be more useful if modified by clinician judgment when used as a screening test in the rapid identification and assessment of patients with the potential for sepsis. ...
INTRODUCTION: Consensus guidelines recommend sepsis screening for adults with systemic inflammatory response syndrome (
Epidemiology of severe sepsis
Mayr FB, et al. Virulence 2014 - Review. PMID 24335434 Free PMC article.
Severe sepsis is a leading cause of death in the United States and the most common cause of death among critically ill patients in non-coronary intensive care units (ICU). ...The type of organism causing severe sepsis is an important determinant of outcome, and gram-positive organisms as a cause of sepsis have increased in frequency over time and are now more common than gram-negative infections. ...
Severe sepsis is a leading cause of death in the United States and the most common cause of death among critically ill
Toward an epidemiology and natural history of SIRS (systemic inflammatory response syndrome).
Bone RC. JAMA 1992 - Review. PMID 1460735
BACKGROUND: New definitions for sepsis and the systemic inflammatory response syndrome (SIRS) have been established. Comparatively little is known, however, about the types of patients who will be included within these new definitions. ...DESIGN: A comparative analysis of patient characteristics in the Methylprednisolone, Veterans Administration Systemic Sepsis, HA-1A, and E5 studies. ...
BACKGROUND: New definitions for sepsis and the systemic inflammatory response syndrome (SIRS) have been established. Comparati …
Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations.
Fleischmann C, et al. Am J Respir Crit Care Med 2016. PMID 26414292
METHODS: We systematically searched 15 international citation databases for population-level estimates of sepsis incidence rates and fatality in adult populations using consensus criteria and published in the last 36 years. ...Our analyses underline the urgent need to implement global strategies to measure sepsis morbidity and mortality, particularly in low- and middle-income countries....
METHODS: We systematically searched 15 international citation databases for population-level estimates of sepsis incidence rat …
Systemic inflammatory response syndrome is more associated with bacteremia in elderly patients with suspected sepsis in emergency departments.
Chou HL, et al. Medicine (Baltimore) 2016 - Clinical Trial. PMID 27930596 Free PMC article.
Early diagnosis of bacteremia for patients with suspected sepsis is 1 way to improve prognosis of sepsis. Systemic inflammatory response syndrome (SIRS) has long been utilized as a screening tool to detect bacteremia by front-line healthcare providers. ...Fever at the triage was most predictive of bacteremia, especially in the elderly patients (aOR: 2.19, 95% CI: 1.81-2.65 in the young-old and aOR: 2.27, 95% CI: 1.95-2.63 in the old), and tachypnea was not predictive of bacteremia among the elderly patients (all P > 0.2).The performance of SIRS to predict bacteremia was more suitable for elderly patients in EDs observed in this study. ...
Early diagnosis of bacteremia for patients with suspected sepsis is 1 way to improve prognosis of sepsis. Systemic i
The Epidemiology of Sepsis in Childhood.
de Souza DC, et al. Shock 2017 - Review. PMID 27454387
BACKGROUND: Sepsis, or systemic inflammatory response to infection, is a major childhood disease and a common cause of death in children. Despite its importance, a global perspective on the epidemiology and mortality of pediatric sepsis across the world is still lacking. ...
BACKGROUND: Sepsis, or systemic inflammatory response to infection, is a major childhood disease and a common ca …
The Changing Epidemiology and Definitions of Sepsis
Kempker JA and Martin GS. Clin Chest Med 2016 - Review. PMID 27229635 Free PMC article.
This article describes the trends in the incidence of and mortality from sepsis in the United States and globally. The article then discusses the known factors associated with increased risk for developing sepsis and the limitations of the current clinical definition and the clinical correlations of the current epidemiology....
This article describes the trends in the incidence of and mortality from sepsis in the United States and globally. The …
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