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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1946 11
1947 10
1948 6
1949 6
1951 14
1952 8
1953 25
1954 50
1955 40
1956 45
1957 34
1958 42
1959 35
1960 42
1961 30
1962 22
1964 4
1965 89
1966 184
1967 203
1968 261
1969 316
1970 304
1971 471
1972 404
1973 485
1974 545
1975 455
1976 436
1977 478
1978 437
1979 556
1980 590
1981 608
1982 688
1983 743
1984 684
1985 718
1986 710
1987 753
1988 723
1989 806
1990 851
1991 934
1992 1013
1993 1060
1994 1209
1995 1364
1996 1333
1997 1483
1998 1562
1999 1606
2000 1670
2001 1736
2002 1659
2003 1891
2004 1991
2005 2094
2006 2290
2007 2379
2008 2415
2009 2501
2010 2810
2011 3088
2012 3203
2013 3337
2014 3283
2015 3205
2016 3023
2017 3016
2018 2899
2019 1488
2020 23
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70,500 results
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Page 1
Severe sepsis and septic shock
Angus DC and van der Poll T. N Engl J Med 2013 - Review. PMID 23984731 Free article.
The inflammatory response in sepsis.
Bosmann M and Ward PA. Trends Immunol 2013 - Review. PMID 23036432 Free PMC article.
The pathophysiology of sepsis and its accompanying systemic inflammatory response syndrome (SIRS) and the events that lead to multiorgan failure and death are poorly understood. It is known that, in septic humans and rodents, the development of SIRS is associated with a loss of the redox balance, but SIRS can also develop in noninfectious states. ...
The pathophysiology of sepsis and its accompanying systemic inflammatory response syndrome (SIRS) and the events that l …
Prevalence of the systemic inflammatory response syndrome in patients who underwent orthognathic surgery.
Silva ML, et al. Oral Maxillofac Surg 2018. PMID 29644541
PURPOSE: The systemic inflammatory response syndrome (SIRS) is the body's response to an insult, such as infection, trauma, burn, and surgical stress linked to several factors deemed potential for multiple organ failure if left untreated. ...RESULTS: From the sample of 80 patients, 26 (32.5% of total) patients had SIRS with higher incidence in females who are 40 years old. ...
PURPOSE: The systemic inflammatory response syndrome (SIRS) is the body's response to an insult, such as infe
The role of the gut microbiota in sepsis.
Haak BW and Wiersinga WJ. Lancet Gastroenterol Hepatol 2017 - Review. PMID 28403983
For decades, the gut was thought to play an important role in sepsis pathogenesis. Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. ...In this Review, we identify knowledge gaps which, if addressed, will help researchers understand the role of the microbiota in sepsis, and provide microbiota-targeted tools to improve sepsis management....
For decades, the gut was thought to play an important role in sepsis pathogenesis. Sepsis is defined as life-threatenin …
Sepsis in children.
Plunkett A and Tong J. BMJ 2015 - Review. PMID 26060188
The Central Role of the Inflammatory Response in Understanding the Heterogeneity of Sepsis-3.
Ding R, et al. Biomed Res Int 2018 - Review. PMID 29977913 Free PMC article.
In sepsis-3, in contrast with sepsis-1, the definition "systemic inflammatory response" has been replaced with "dysregulated host response", and "systemic inflammatory response syndrome" (SIRS) has been replaced with "sequential organ failure assessment" (SOFA). ...An unbalanced pro- and anti-inflammatory response, inflammatory resolution disorder, and persistent inflammation play important roles in the acute and/or chronic phases of sepsis. ...
In sepsis-3, in contrast with sepsis-1, the definition "systemic inflammatory response" has been replaced with "
The systemic inflammatory response syndrome: definitions and aetiology.
Nyström PO. J Antimicrob Chemother 1998 - Review. PMID 9511080
Systemic inflammatory response syndrome (SIRS) is the clinical expression of the action of complex intrinsic mediators of the acute phase reaction. ...SIRS and MODS are graded expressions of the inflammation associated with acute illness. Mild forms are frequent in general wards for both medical and surgical patients but those with severe forms require intensive care. ...
Systemic inflammatory response syndrome (SIRS) is the clinical expression of the action of complex intrinsic med
Sepsis-induced immunoparalysis: mechanisms, markers, and treatment options.
Hamers L, et al. Minerva Anestesiol 2015 - Review. PMID 24878876 Free article.
Sepsis remains the leading cause of death in the ICU. Considering the key role of the immune system in sepsis, immunomodulation represents an attractive target for adjunctive therapy. ...As such, identification of patients suffering from immunoparalysis using biomarkers is of utmost importance to guide immunostimulatory treatment. ...
Sepsis remains the leading cause of death in the ICU. Considering the key role of the immune system in sepsis, …
Innate immune responses to danger signals in systemic inflammatory response syndrome and sepsis.
Castellheim A, et al. Scand J Immunol 2009 - Review. PMID 19439008 Free article.
The systemic immune response induced by non-infectious agents is called systemic inflammatory response syndrome (SIRS) and infection-induced systemic immune response is called sepsis. ...In critical illness, the acute immune response is organized and executed by innate immunity influenced by the neuroendocrine system. ...
The systemic immune response induced by non-infectious agents is called systemic inflammatory
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