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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 1
1996 1
1998 1
1999 3
2000 1
2001 1
2004 1
2007 1
2008 1
2009 1
2011 1
2012 1
2015 1
2021 1
2023 0
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17 results
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Page 1
The molecular landscape of well differentiated retroperitoneal liposarcoma.
Tyler R, Dilworth MP, James J, Blakeway D, Stockton JD, Morton DG, Taniere P, Gourevitch D, Desai A, Beggs AD. Tyler R, et al. J Pathol. 2021 Oct;255(2):132-140. doi: 10.1002/path.5749. Epub 2021 Aug 4. J Pathol. 2021. PMID: 34156092
Recurrent amplification of HGMA2 was observed, although this was in fact part of a general amplification of the region around this gene. Recurrent gene fusions in HGMA2, SDHA, TSPAN31, and MDM2 were also observed as well as consistent rearrangements between chromosome 6 an …
Recurrent amplification of HGMA2 was observed, although this was in fact part of a general amplification of the region around this gene. Rec …
Carboxypeptidase M: a biomarker for the discrimination of well-differentiated liposarcoma from lipoma.
Erickson-Johnson MR, Seys AR, Roth CW, King AA, Hulshizer RL, Wang X, Asmann YW, Lloyd RV, Jacob EK, Oliveira AM. Erickson-Johnson MR, et al. Mod Pathol. 2009 Dec;22(12):1541-7. doi: 10.1038/modpathol.2009.149. Epub 2009 Oct 9. Mod Pathol. 2009. PMID: 19820690 Free article.
These abnormal chromosomes are mainly composed of amplified genomic sequences derived from chromosome 12q13-15, and contain several genes, including MDM2, CDK4 (SAS), TSPAN31, HMGA2, and others. MDM2 is consistently amplified in well-differentiated liposarcomas/atypical li …
These abnormal chromosomes are mainly composed of amplified genomic sequences derived from chromosome 12q13-15, and contain several genes, i …
Characterization of the 12q amplicons in lipomatous soft tissue tumors by multiplex ligation-dependent probe amplification-based copy number analysis.
Creytens D, Van Gorp J, Speel EJ, Ferdinande L. Creytens D, et al. Anticancer Res. 2015 Apr;35(4):1835-42. Anticancer Res. 2015. PMID: 25862836
RESULTS: We recorded several amplified genes of 12q13-15, including miR-26a-2, a gene not well studied in liposarcoma, and the well-known and previously described genes murine double minute 2 (MDM2), YEATS domain-containing protein 4 (YEATS4), high-mobility AT-hook 2 (HMGA2), cyc …
RESULTS: We recorded several amplified genes of 12q13-15, including miR-26a-2, a gene not well studied in liposarcoma, and the well-known an …
A newly characterized human well-differentiated liposarcoma cell line contains amplifications of the 12q12-21 and 10p11-14 regions.
Pedeutour F, Maire G, Pierron A, Thomas DM, Garsed DW, Bianchini L, Duranton-Tanneur V, Cortes-Maurel A, Italiano A, Squire JA, Coindre JM. Pedeutour F, et al. Virchows Arch. 2012 Jul;461(1):67-78. doi: 10.1007/s00428-012-1256-5. Epub 2012 Jun 8. Virchows Arch. 2012. PMID: 22678079
We analyzed the mRNA expression status by real-time reverse transcription polymerase chain reaction for six genes from this amplicon: MDM2, HMGA2, CDK4, TSPAN31, WIF1, and YEATS4. mRNA overexpression was correlated with genomic amplification. ...
We analyzed the mRNA expression status by real-time reverse transcription polymerase chain reaction for six genes from this amplicon: MDM2, …
Analysis of 12q13-15 genes in parosteal osteosarcoma.
Gamberi G, Ragazzini P, Benassi MS, Ferrari C, Sollazzo MR, Molendini L, Merli M, Magagnoli G, Ruggieri P, Balladelli A, Orlando C, Bacchini P, Pazzagli M, Picci P. Gamberi G, et al. Clin Orthop Relat Res. 2000 Aug;(377):195-204. doi: 10.1097/00003086-200008000-00026. Clin Orthop Relat Res. 2000. PMID: 10943202
High-resolution genomic mapping reveals consistent amplification of the fibroblast growth factor receptor substrate 2 gene in well-differentiated and dedifferentiated liposarcoma.
Wang X, Asmann YW, Erickson-Johnson MR, Oliveira JL, Zhang H, Moura RD, Lazar AJ, Lev D, Bill K, Lloyd RV, Yaszemski MJ, Maran A, Oliveira AM. Wang X, et al. Genes Chromosomes Cancer. 2011 Nov;50(11):849-58. doi: 10.1002/gcc.20906. Epub 2011 Jul 26. Genes Chromosomes Cancer. 2011. PMID: 21793095
Cytogenetically, WDLS is characterized by the presence of ring or giant rod chromosomes containing several amplified genes, including MDM2, TSPAN31, CDK4, and others mainly derived from chromosome bands 12q13-15. ...
Cytogenetically, WDLS is characterized by the presence of ring or giant rod chromosomes containing several amplified genes, including MDM2, …
Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma.
Ragazzini P, Gamberi G, Benassi MS, Orlando C, Sestini R, Ferrari C, Molendini L, Sollazzo MR, Merli M, Magagnoli G, Bertoni F, Bohling T, Pazzagli M, Picci P. Ragazzini P, et al. Cancer Detect Prev. 1999;23(2):129-36. doi: 10.1046/j.1525-1500.1999.09907.x. Cancer Detect Prev. 1999. PMID: 10101594
HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon.
Italiano A, Bianchini L, Keslair F, Bonnafous S, Cardot-Leccia N, Coindre JM, Dumollard JM, Hofman P, Leroux A, Mainguené C, Peyrottes I, Ranchere-Vince D, Terrier P, Tran A, Gual P, Pedeutour F. Italiano A, et al. Int J Cancer. 2008 May 15;122(10):2233-41. doi: 10.1002/ijc.23380. Int J Cancer. 2008. PMID: 18214854 Free article.
In addition, using quantitative RT-PCR we studied the expression of MDM2, CDK4, DDIT3 (CHOP/GADD153), DYRK2, HMGA2, TSPAN31 and YEATS4 (GAS41) in 11 cases. We showed that CDK4 (12q14.1) belonged to a distinct amplicon than MDM2 (12q15). ...
In addition, using quantitative RT-PCR we studied the expression of MDM2, CDK4, DDIT3 (CHOP/GADD153), DYRK2, HMGA2, TSPAN31 and YEATS …
17 results