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Microbiological and clinical effects of probiotics and antibiotics on nonsurgical treatment of chronic periodontitis: a randomized placebo- controlled trial with 9-month follow-up.
Morales A, et al. J Appl Oral Sci 2018 - Clinical Trial. PMID 29364340 Free PMC article.
The aim of this double-blind, placebo-controlled and parallel- arm randomized clinical trial was to evaluate the effects of Lactobacillus rhamnosus SP1-containing probiotic sachet and azithromycin tablets as an adjunct to nonsurgical therapy in clinical parameters and in presence and levels of Tannerella forsythia, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. ...
The aim of this double-blind, placebo-controlled and parallel- arm randomized clinical trial was to evaluate the effects of Lactobaci …
Comparative evaluation of antiplaque and antigingivitis effects of an herbal and chlorine dioxide mouthwashes: A clinicomicrobiological study.
Siddeshappa ST, et al. Indian J Dent Res 2018 - Clinical Trial. PMID 29442084 Free article.
The microbial colony-forming units were assessed at baseline, 7(th) day, 14(th) day, and 21(st) day for Streptococcus mutans, Tannerella forsythia, and Fusobacterium nucleatum. ...
The microbial colony-forming units were assessed at baseline, 7(th) day, 14(th) day, and 21(st) day for Streptococcus mutans, Tannerella
Microbiologic Response to Periodontal Therapy and Multivariable Prediction of Clinical Outcome
Mombelli A, et al. J Periodontol 2017. PMID 28844191
BACKGROUND: This study assesses the microbiologic effects of a two-phase antimicrobial periodontal therapy and tested microbiologic, clinical, and biologic markers as prognostic indicators for clinical success. ...RESULTS: T1 decreased the counts of Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia (Pi), and Treponema denticola significantly more in group A than group B. ...
BACKGROUND: This study assesses the microbiologic effects of a two-phase antimicrobial periodontal therapy and tested microbiologic, …
Efficacy of β-caryophyllene for periodontal disease related factors
Yoo HJ and Jwa SK. Arch Oral Biol 2019. PMID 30826504
OBJECTIVE: This study aimed to investigate the antimicrobial activity of β-caryophyllene against periodontopathogens as well as its inhibitory effects on the expression of inflammatory cytokines and production of volatile sulfur compounds by lipopolysaccharide and periodontopathogenic enzymes, respectively. DESIGN: The antimicrobial activity of β-caryophyllene againstPorphyromonas gingivalis, Tannerella forsythia, and Treponema denticola was investigated via a susceptibility assay using a microplate reader. ...
OBJECTIVE: This study aimed to investigate the antimicrobial activity of β-caryophyllene against periodontopathogens as well as its inhibito …
In vitro Resistance Testing of Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia to Triclosan.
Farsi D and Tanner A. J Contemp Dent Pract 2016. PMID 27340161
AIM: To determine the sensitivity of Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia to triclosan, and determine if these bacteria develop resistance to triclosan upon prolonged exposure. MATERIALS AND METHODS: Susceptibility to triclosan was tested against three periodontal pathogens P. gingivalis, P. intermedia, and T. forsythia. ...
AIM: To determine the sensitivity of Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia to triclosan, a …
Effect of Resveratrol on periodontal pathogens during experimental periodontitis in rats
Cirano FR, et al. Braz Oral Res 2016. PMID 27901209 Free article.
Then, the presence and concentrations of Porphyromonas gingivalis, Tannerella forsythia and Aggregatibacter actinomycetemcomitans in the cotton ligatures collected from the first molars were evaluated using real-time PCR. Inter-group comparisons of the microbiological outcomes revealed that no differences were detected for P. gingivalis, T. forsythia and A. actinomycetemcomitans levels (p > 0.05). ...
Then, the presence and concentrations of Porphyromonas gingivalis, Tannerella forsythia and Aggregatibacter actinomycetemcomit …
Inhibition of malodorous gas formation by oral bacteria with cetylpyridinium and zinc chloride
Kang JH, et al. Arch Oral Biol 2017. PMID 28987726
DESIGN: Minimum inhibitory concentrations (MIC) and growth curves were determined for ZnCl(2), CPC, and CPC with ZnCl(2) solutions against eight oral microorganisms (Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella intermedia, Treponema denticola, Tannerella forsythia, Staphylococcus aureus and Streptococcus mutans) known to be involved in the pathophysiology of both halitosis and periodontal disease. ...Production of CH(3)SH, the most malodorous component among the three major VSCs from mouth air was evident in F. nucleatum and T. forsythia. ...
DESIGN: Minimum inhibitory concentrations (MIC) and growth curves were determined for ZnCl(2), CPC, and CPC with ZnCl(2) solutions against e …
Microbiological and Clinical Effects of Sitafloxacin and Azithromycin in Periodontitis Patients Receiving Supportive Periodontal Therapy.
Nakajima T, et al. Antimicrob Agents Chemother 2016. PMID 26729495 Free PMC article.
The microbiological and clinical parameters were examined until 12 months after the systemic administration of each drug. The concentration of each drug in periodontal pockets and the antimicrobial susceptibility of clinical isolates were also analyzed. The proportions of red complex bacteria, i.e., Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia, which are the representative periodontopathic bacteria, were significantly reduced at 1 month and remained lower at 12 months than those at baseline in both the STFX and AZM groups. ...
The microbiological and clinical parameters were examined until 12 months after the systemic administration of each drug. The concent …
New bicyclic brominated furanones as potent autoinducer-2 quorum-sensing inhibitors against bacterial biofilm formation
Park JS, et al. Eur J Med Chem 2017. PMID 28554093
., 3-(dibromomethylene)isobenzofuran-1(3H)-one derivatives, and demonstrate their inhibitory activities against biofilm formation by periodontopathogens, including F. nucleatum, Porphyromonas gingivalis, and Tannerella forsythia....
., 3-(dibromomethylene)isobenzofuran-1(3H)-one derivatives, and demonstrate their inhibitory activities against biofilm formation by periodo …
Influence of a triclosan toothpaste on periodontopathic bacteria and periodontitis progression in cardiovascular patients: a randomized controlled trial
Seymour GJ, et al. J Periodontal Res 2017 - Clinical Trial. PMID 26932733
Concurrent load of the periodontal pathogens Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Tannerella forsythia and Porphyromonas gingivalis was determined, using quantitative real-time PCR, in 437 patients with baseline plaque samples. ...In contrast, the prevalence of T. forsythia and P. gingivalis showed more variability; however, there was no significant difference between the groups, at any time point, in the prevalence of any organism. ...
Concurrent load of the periodontal pathogens Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Tannerella forsythia
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