Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1950 1
1956 2
1958 1
1961 1
1962 2
1963 3
1964 1
1965 1
1966 1
1967 1
1969 1
1970 1
1972 1
1973 2
1975 4
1976 5
1977 3
1978 3
1979 2
1980 5
1981 9
1982 7
1983 6
1984 6
1985 8
1986 6
1987 10
1988 8
1989 10
1990 11
1991 7
1992 5
1993 8
1994 8
1995 5
1996 14
1997 11
1998 18
1999 14
2000 10
2001 19
2002 10
2003 11
2004 14
2005 18
2006 16
2007 13
2008 6
2009 16
2010 10
2011 16
2012 20
2013 29
2014 24
2015 18
2016 14
2017 17
2018 16
2019 18
2020 24
2021 25
2022 30
2023 15
2024 21
2025 17
2026 27

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

629 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "Testicular failure primary"
Page 1
Primary Testicular Failure.
Behre HM, Bergmann M, Simoni M, Tüttelmann F. Behre HM, et al. 2015 Aug 30. In: Feingold KR, Adler RA, Ahmed SF, Anawalt B, Blackman MR, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hamilton E, Hofland J, Jan de Beur S, Kalra S, Kaltsas G, Kapoor N, Kim M, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, Muzumdar R, Purnell J, Rey R, Sahay R, Shah AS, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. 2015 Aug 30. In: Feingold KR, Adler RA, Ahmed SF, Anawalt B, Blackman MR, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hamilton E, Hofland J, Jan de Beur S, Kalra S, Kaltsas G, Kapoor N, Kim M, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, Muzumdar R, Purnell J, Rey R, Sahay R, Shah AS, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905302 Free Books & Documents. Review.
Primary testicular failure may result in endocrine failure, leading to testosterone deficiency or exocrine failure causing impaired spermatogenesis and subsequently male infertility. While some aspects of primary testicular fail …
Primary testicular failure may result in endocrine failure, leading to testosterone deficiency or exocrine fa …
Primary gonadal failure.
Ladjouze A, Donaldson M. Ladjouze A, et al. Best Pract Res Clin Endocrinol Metab. 2019 Jun;33(3):101295. doi: 10.1016/j.beem.2019.101295. Epub 2019 Jul 12. Best Pract Res Clin Endocrinol Metab. 2019. PMID: 31327696 Review.
The term primary gonadal failure encompasses not only testicular insufficiency in 46,XY males and ovarian insufficiency in 46,XX females, but also those disorders of sex development (DSD) which result in gender assignment that is at variance with the genotype …
The term primary gonadal failure encompasses not only testicular insufficiency in 46,XY males and ovarian insufficiency …
Genetics of Azoospermia.
Cioppi F, Rosta V, Krausz C. Cioppi F, et al. Int J Mol Sci. 2021 Mar 23;22(6):3264. doi: 10.3390/ijms22063264. Int J Mol Sci. 2021. PMID: 33806855 Free PMC article. Review.
The diagnostic yield of genetic tests in azoospermia is different in the different etiological categories, with the highest in Congenital Bilateral Absence of Vas Deferens (90%) and the lowest in Non-Obstructive Azoospermia (NOA) due to primary testicular failure …
The diagnostic yield of genetic tests in azoospermia is different in the different etiological categories, with the highest in Congenital Bi …
First-line treatment for primary testicular diffuse large B-cell lymphoma with rituximab-CHOP, CNS prophylaxis, and contralateral testis irradiation: final results of an international phase II trial.
Vitolo U, Chiappella A, Ferreri AJ, Martelli M, Baldi I, Balzarotti M, Bottelli C, Conconi A, Gomez H, Lopez-Guillermo A, Martinelli G, Merli F, Novero D, Orsucci L, Pavone V, Ricardi U, Storti S, Gospodarowicz MK, Cavalli F, Sarris AH, Zucca E. Vitolo U, et al. J Clin Oncol. 2011 Jul 10;29(20):2766-72. doi: 10.1200/JCO.2010.31.4187. Epub 2011 Jun 6. J Clin Oncol. 2011. PMID: 21646602 Free article. Clinical Trial.
PURPOSE: Primary testicular lymphoma (PTL) has poor prognosis with failures in contralateral testis, CNS, and extranodal sites. ...Ten patients died: lymphoma (n = 6), secondary leukemia (n = 2), heart failure (n = 1), and gastric cancer (n = 1). Grade 3 to 4 …
PURPOSE: Primary testicular lymphoma (PTL) has poor prognosis with failures in contralateral testis, CNS, and extranodal sites …
Male hypogonadism.
Basaria S. Basaria S. Lancet. 2014 Apr 5;383(9924):1250-63. doi: 10.1016/S0140-6736(13)61126-5. Epub 2013 Oct 10. Lancet. 2014. PMID: 24119423 Review.
Male hypogonadism is a clinical syndrome that results from failure to produce physiological concentrations of testosterone, normal amounts of sperm, or both. Hypogonadism may arise from testicular disease (primary hypogonadism) or dysfunction of the hypothala …
Male hypogonadism is a clinical syndrome that results from failure to produce physiological concentrations of testosterone, normal am …
Late-Onset Hypogonadism as Primary Testicular Failure.
Swee DS, Gan EH. Swee DS, et al. Front Endocrinol (Lausanne). 2019 Jun 12;10:372. doi: 10.3389/fendo.2019.00372. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 31244778 Free PMC article. No abstract available.
Adult-Onset Hypogonadism.
Khera M, Broderick GA, Carson CC 3rd, Dobs AS, Faraday MM, Goldstein I, Hakim LS, Hellstrom WJ, Kacker R, Köhler TS, Mills JN, Miner M, Sadeghi-Nejad H, Seftel AD, Sharlip ID, Winters SJ, Burnett AL. Khera M, et al. Mayo Clin Proc. 2016 Jul;91(7):908-26. doi: 10.1016/j.mayocp.2016.04.022. Epub 2016 Jun 21. Mayo Clin Proc. 2016. PMID: 27343020 Free article. Review.
In August 2015, an expert colloquium commissioned by the Sexual Medicine Society of North America (SMSNA) convened in Washington, DC, to discuss the common clinical scenario of men who present with low testosterone (T) and associated signs and symptoms accompanied by low or norma …
In August 2015, an expert colloquium commissioned by the Sexual Medicine Society of North America (SMSNA) convened in Washington, DC, to dis …
Azoospermia.
Sharma M, Leslie SW. Sharma M, et al. 2023 Nov 18. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2023 Nov 18. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 35201719 Free Books & Documents.
NOA is most often due to severe defects in spermatogenesis, which are frequently due to primary testicular failure or dysfunction. It can also result from dysfunction of the pituitary or hypothalamus. ...Advanced assisted reproductive techniques can often tre …
NOA is most often due to severe defects in spermatogenesis, which are frequently due to primary testicular failure or d …
Whole exome sequencing analysis of 167 men with primary infertility.
Zhou H, Yin Z, Ni B, Lin J, Luo S, Xie W. Zhou H, et al. BMC Med Genomics. 2024 Sep 12;17(1):230. doi: 10.1186/s12920-024-02005-3. BMC Med Genomics. 2024. PMID: 39267058 Free PMC article.
BACKGROUND: Spermatogenic failure is one of the leading causes of male infertility and its genetic etiology has not yet been fully understood. METHODS: The study screened a cohort of patients (n = 167) with primary male infertility in contrast to 210 normally fertil …
BACKGROUND: Spermatogenic failure is one of the leading causes of male infertility and its genetic etiology has not yet been fully un …
Testicular steroid sulfatase overexpression is associated with Leydig cell dysfunction in primary spermatogenic failure.
Lardone MC, Reyes IN, Ortiz E, Piottante A, Palma C, Ebensperger M, Castro A. Lardone MC, et al. Andrology. 2021 Mar;9(2):657-664. doi: 10.1111/andr.12950. Epub 2020 Dec 30. Andrology. 2021. PMID: 33290605 Free article.
However, it is unknown whether the sulfatase pathway contributes to the increased availability of active estrogens in patients with primary spermatogenic failure. OBJECTIVES: To assess estrogen sulfotransferase (SULT1E1) and steroid sulfatase (STS) mRNA abundance in …
However, it is unknown whether the sulfatase pathway contributes to the increased availability of active estrogens in patients with prima …
629 results