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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 7
1952 9
1953 12
1954 18
1955 16
1956 12
1957 15
1958 13
1959 20
1960 14
1961 16
1962 11
1964 4
1966 18
1967 18
1968 18
1969 24
1970 19
1971 27
1972 18
1973 22
1974 43
1975 22
1976 33
1977 29
1978 50
1979 50
1980 49
1981 43
1982 40
1983 40
1984 50
1985 38
1986 39
1987 69
1988 30
1989 37
1990 40
1991 26
1992 41
1993 47
1994 34
1995 25
1996 23
1997 33
1998 38
1999 25
2000 19
2001 18
2002 21
2003 24
2004 22
2005 35
2006 45
2007 45
2008 55
2009 47
2010 46
2011 40
2012 46
2013 71
2014 66
2015 56
2016 50
2017 71
2018 57
2019 42
2020 1
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2,087 results
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Page 1
Imbalance of erythropoiesis and iron metabolism in patients with thalassemia.
Huang Y, et al. Int J Med Sci 2019. PMID 30745811 Free PMC article.
Aim: This study aimed to evaluate the imbalance of erythropoiesis and iron metabolism in patients with thalassemia. Methods: 192 patients with non-transfusion-dependent thalassemia (NTDT), 94 patients with transfusion-dependent thalassemia (TDT) and 101 healthy controls were recruited between June 2013 and December 2016 in the Hematology Department, the First Affiliated Hospital of Guangxi Medical University. ...Hepcidin levels and ratios of hepcidin to erythropoietic activity and to iron biomarker levels were lower in patients with β-thalassemia intermedia or hemoglobin (Hb) E/β-thalassemia than in patients with HbH disease. ...
Aim: This study aimed to evaluate the imbalance of erythropoiesis and iron metabolism in patients with thalassemia. Methods: 192 pati …
Analysis of Glycosylation Profiles of Serum Glycoprotein from Iron Overload Thalassemia.
Huang A, et al. Clin Lab 2018. PMID 30146840
METHODS: This study enrolled iron overload α/β-thalassemia patients and no iron overload α/β-thalassemia patients. Lectin microarray was used to detect the alteration of protein glycosylation. ...RESULTS: In this study, 19 differentiating lectins were screened from the iron overload α-thalassemia group, and 15 were screened from the iron overload β-thalassemia group. ...
METHODS: This study enrolled iron overload α/β-thalassemia patients and no iron overload α/β-thalassemia patients. Lectin micr …
Where Did That Peak Come From?
Rutherford NJ, et al. Clin Chem 2018. PMID 30154200
Is there a difference in phenotype between males and females with non-transfusion-dependent thalassemia? A cross-sectional evaluation.
Marsella M, et al. Hematology 2018 - Clinical Trial. PMID 29303050
OBJECTIVES: Non-transfusion-dependent thalassemia includes a variety of phenotypes and genotypes that rarely require regular transfusions. ...CONCLUSION: This data should be considered in studies with experimental treatments aiming to correct anemia in patients with non-transfusion-dependent thalassemia. ...
OBJECTIVES: Non-transfusion-dependent thalassemia includes a variety of phenotypes and genotypes that rarely require regular transfus …
Glucose Homeostasis Markers in Beta-Thalassemia.
Gomber S, et al. J Pediatr Hematol Oncol 2018. PMID 29668553
Hence, the study was carried out to find out which marker holds promise among Indian beta-thalassemic children. METHODS: In this case-control study, 60 diagnosed cases of beta-thalassemia major and equal number of normal controls who were ≥8 years of age were enrolled. ...Despite this finding, HbA1c continues to be a good marker for worsening glucose homeostasis in thalassemics as higher values were found in thalassemics with abnormal glucose tolerance compared with their normal counterparts. ...
Hence, the study was carried out to find out which marker holds promise among Indian beta-thalassemic children. METHODS: In this case …
Impact of hydroxyurea therapy on serum fatty acids of β-thalassemia patients.
Iqbal A, et al. Metabolomics 2018. PMID 30830370
Therefore, in the present study we have carried out the quantification of thirteen free fatty acids to disclose the prognosis of HU in β-thalassemia. ...HbF induction in β-thalassemia patients....
Therefore, in the present study we have carried out the quantification of thirteen free fatty acids to disclose the prognosis of HU in β- …
Thalassemia among blood donors at the Hospital Universiti Sains Malaysia.
Rosline H, et al. Southeast Asian J Trop Med Public Health 2006. PMID 17120978
The types of thalassemias detected were Hb E, 11.25% (n=9/80) and beta thalassemia trait, 5% (n=4/80). Among the thalassemias detected, the Hb E hemoglobinopathy was comprised of Hb E/ alpha-thalassemia (38.5%: n=5), Hb E /beta-thalassemia (23.1%: n=3), Hb E trait (7.6%: n=1) and beta-thalassemia (30.8%: n=4). ...Further studies are required to look at the effects of donated thalassemic blood....
The types of thalassemias detected were Hb E, 11.25% (n=9/80) and beta thalassemia trait, 5% (n=4/80). Among the thalassemi
Normal hemostatic parameters in children and young adults with α-thalassemia diseases.
Sirachainan N, et al. Thromb Res 2016. PMID 27572718
Thalassemia intermedia (TI), a non-transfusion dependent thalassemia, is divided into α-thalassemia, such as HbH disease, and β-thalassemia diseases, such as HbE/β(+) thromboembolism (TE) in TI has been mostly reported in β-thalassemia diseases with incidence rates of 3.9-29%. The present study enrolled 60 patients with α-thalassemia intermedia. The control groups were thalassemia major (TM) consisting of 17 patients diagnosed with β-thalassemia diseases, 24 patients diagnosed with splenectomized β-thalassemia diseases and 25 normal subjects. ...
Thalassemia intermedia (TI), a non-transfusion dependent thalassemia, is divided into α-thalassemia, such as HbH diseas
Prothrombotic markers in Thalassemia major patients: A paradigm shift.
Sultan S, et al. Med J Malaysia 2018. PMID 30121679 Free article.
BACKGROUND: It is being increasingly recognised that thalassemia major patients, like intermedia, have increased propensity for thromboembolism. ...
BACKGROUND: It is being increasingly recognised that thalassemia major patients, like intermedia, have increased propensity for throm …
Rheological behaviour of red blood cells in beta and deltabeta thalassemia trait.
Vayá A, et al. Clin Hemorheol Microcirc 2003. PMID 12652012
In major and intermediate thalassemia a decrease in erythrocyte deformability and increased erythrocyte aggregability has been described, but few studies have dealt with the question of rheological red blood cell behaviour in minor beta and deltabeta thalassemia carriers, mostly in deltabeta, because it is a less common entity. ...Minor beta thalassemia carriers showed lower EI than deltabeta carriers (p<0.001). Erythrocyte aggregability measured with the Myrenne aggregometer was significantly lower in both thalassemic groups than in controls (p<0.001), although no significant differences could be observed between both thalassemic groups. ...
In major and intermediate thalassemia a decrease in erythrocyte deformability and increased erythrocyte aggregability has been descri …
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