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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1966 1
1967 3
1968 7
1969 5
1970 5
1971 10
1972 8
1973 12
1974 6
1975 10
1976 10
1977 10
1978 5
1979 6
1980 10
1981 10
1982 12
1983 12
1984 15
1985 11
1986 15
1987 23
1988 29
1989 41
1990 48
1991 37
1992 45
1993 39
1994 66
1995 90
1996 86
1997 96
1998 105
1999 105
2000 107
2001 110
2002 95
2003 110
2004 141
2005 169
2006 173
2007 163
2008 153
2009 162
2010 165
2011 160
2012 247
2013 249
2014 303
2015 351
2016 334
2017 297
2018 269
2019 159
2020 2
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4,487 results
Results by year
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Page 1
Integrated genomic characterization of papillary thyroid carcinoma.
Cancer Genome Atlas Research Network . Cell 2014. PMID 25417114 Free PMC article.
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we describe the genomic landscape of 496 PTCs. ...Our results propose a reclassification of thyroid cancers into molecular subtypes that better reflect their underlying signaling and differentiation properties, which has the potential to improve their pathological classification and better inform the management of the disease....
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we describe the genomic landscape of 496 PT …
[Genetics of thyroid nodules and thyroid carcinoma].
Führer D. Internist (Berl) 2018 - Review. PMID 29931438 German.
While the mutation rate is generally low in differentiated thyroid cancers, poorly differentiated and anaplastic thyroid cancers show a high mutation load. The identification of somatic mutations in fine needle aspirates can be helpful for the differential diagnostics of thyroid nodules; however, a prognostic contribution is less certain. ...
While the mutation rate is generally low in differentiated thyroid cancers, poorly differentiated and anaplastic thyroid cance …
ROLE OF MOLECULAR MARKERS IN THYROID NODULE MANAGEMENT: THEN AND NOW.
Nikiforov YE. Endocr Pract 2017 - Review. PMID 28534687
This knowledge provides the basis for establishing and further improving molecular tests for thyroid nodules and cancer and for the introduction of new entities such as noninvasive follicular thyroid neoplasm with papillary-like nuclear features. ...ABBREVIATIONS: FNA = fine-needle aspiration miRNA = micro RNA NGS = next-generation sequencing NIFTP = noninvasive follicular thyroid neoplasm with papillary-like nuclear features NPV = negative predictive value PPV = positive predictive value PTC = papillary thyroid carcinoma RAI = radioactive iodine....
This knowledge provides the basis for establishing and further improving molecular tests for thyroid nodules and cancer and for the i …
Molecular genetics of thyroid cancer.
Rebaї M and Rebaї A. Genet Res (Camb) 2016 - Review. PMID 27174043 Free PMC article.
The pathogenesis of the development and progression of thyroid cancer (TC) is far from being clear at present. Accumulated evidence suggests that it is a complex polygenic disorder for which genetic factors play an important role in disease aetiology. ...
The pathogenesis of the development and progression of thyroid cancer (TC) is far from being clear at present. Accumulated evidence s …
Molecular pathogenesis and mechanisms of thyroid cancer.
Xing M. Nat Rev Cancer 2013 - Review. PMID 23429735 Free PMC article.
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in understanding its molecular pathogenesis in recent years, as best exemplified by the elucidation of the fundamental role of several major signalling pathways and related molecular derangements. ...Many of these molecular alterations represent novel diagnostic and prognostic molecular markers and therapeutic targets for thyroid cancer, which provide unprecedented opportunities for further research and clinical development of novel treatment strategies for this cancer....
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in understanding its molecular pathogenesis in rece
Molecular Genetics of Thyroid Cancer in Children and Adolescents.
Bauer AJ. Endocrinol Metab Clin North Am 2017 - Review. PMID 28476228
There has been a steady incorporation of powerful new molecular tools into the evaluation and management of thyroid nodules and thyroid cancer. ...However, additional investment and efforts are needed to define the genomic landscape for pediatric DTC with the goal of improving preoperative diagnostic accuracy as well as stratifying treatment in an effort to reduce complications of therapy....
There has been a steady incorporation of powerful new molecular tools into the evaluation and management of thyroid nodules an …
Thyroid Cancer in the Pediatric Population.
Paulson VA, et al. Genes (Basel) 2019 - Review. PMID 31540418 Free PMC article.
Thyroid cancer is rare in the pediatric population, but thyroid carcinomas occurring in children carry a unique set of clinical, pathologic, and molecular characteristics. ...Differences are also seen in pediatric follicular thyroid cancer, although there are few studies of non-papillary pediatric thyroid tumors published in the literature due to their rarity, and in medullary carcinoma, which is most frequently diagnosed in the pediatric population in the setting of prophylactic thyroidectomies for known multiple endocrine neoplasia syndromes. ...
Thyroid cancer is rare in the pediatric population, but thyroid carcinomas occurring in children carry a unique set of clinica
Papillary Thyroid Cancer: Genetic Alterations and Molecular Biomarker Investigations.
Abdullah MI, et al. Int J Med Sci 2019 - Review. PMID 30911279 Free PMC article.
Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is usually contained within the thyroid gland and generally biologically indolent. Prognosis of the cancer is excellent, with less than 2% mortality at 5 years. ...
Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of the thyroid. It is also one of th …
Performance of a Multigene Genomic Classifier in Thyroid Nodules With Indeterminate Cytology: A Prospective Blinded Multicenter Study.
Steward DL, et al. JAMA Oncol 2019 - Clinical Trial. PMID 30419129 Free PMC article.
IMPORTANCE: Approximately 20% of fine-needle aspirations (FNA) of thyroid nodules have indeterminate cytology, most frequently Bethesda category III or IV. ...RESULTS: Of the 286 cytologically indeterminate nodules, 206 (72%) were benign, 69 (24%) malignant, and 11 (4%) noninvasive follicular thyroid neoplasms with papillary-like nuclei (NIFTP). ...
IMPORTANCE: Approximately 20% of fine-needle aspirations (FNA) of thyroid nodules have indeterminate cytology, most frequently …
Molecular Diagnostic Evaluation of Thyroid Nodules.
Mayson SE and Haugen BR. Endocrinol Metab Clin North Am 2019 - Review. PMID 30717912
The historical management approach for many patients with indeterminate thyroid nodule fine needle aspiration cytology is a diagnostic lobectomy or thyroidectomy. ...Molecular testing is a diagnostic tool that can be used to help guide the clinical management of thyroid nodules with indeterminate cytology results. ...
The historical management approach for many patients with indeterminate thyroid nodule fine needle aspiration cytology is a di …
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