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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 3
2004 19
2005 457
2006 1542
2007 1852
2008 1936
2009 2158
2010 2342
2011 2593
2012 2700
2013 2771
2014 2745
2015 2689
2016 2598
2017 2431
2018 2312
2019 1092
2020 21
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28,074 results
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Page 1
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity.
Kawai T and Akira S. Immunity 2011 - Review. PMID 21616434 Free article.
Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that play a central role in host cell recognition and responses to microbial pathogens. TLR-mediated recognition of components derived from a wide range of pathogens and their role in the subsequent initiation of innate immune responses is widely accepted; however, the recent discovery of non-TLR PRRs, such as C-type lectin receptors, NOD-like receptors, and RIG-I-like receptors, suggests that many aspects of innate immunity are more sophisticated and complex. ...
Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that play a central role in host cell rec
Toll-like receptors.
Moresco EM, et al. Curr Biol 2011 - Review. PMID 21741580 Free article.
Toll-like receptor signaling.
Lim KH and Staudt LM. Cold Spring Harb Perspect Biol 2013 - Review. PMID 23284045 Free PMC article.
Toll-like receptors sense pathogen-associated molecular patterns (e.g., lipopolysaccharides) and trigger gene-expression changes that ultimately eradicate the invading microbes....
Toll-like receptors sense pathogen-associated molecular patterns (e.g., lipopolysaccharides) and trigger gene-expression chang
Toll-Like Receptors: Regulators of the Immune Response in the Human Gut.
Hug H, et al. Nutrients 2018 - Review. PMID 29438282 Free PMC article.
Toll-like receptors (TLRs) are powerful molecular regulators by which the immune system may "sense" the environment and protect the host from pathogens or endogenous threats. ...
Toll-like receptors (TLRs) are powerful molecular regulators by which the immune system may "sense" the environment and protec
Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis.
Roh YS and Seki E. J Gastroenterol Hepatol 2013 - Review. PMID 23855294 Free PMC article.
Activation of innate immune systems including Toll-like receptor (TLR) signaling is a key in chronic liver disease. Recent studies suggest that gut microflora-derived bacterial products (i.e. lipopolysaccharide [LPS], bacterial DNA) and endogenous substances (i.e. high-mobility group protein B1 [HMGB1], free fatty acids) released from damaged cells activate hepatic TLRs that contribute to the development of alcoholic (ASH) and non-alcoholic steatohepatitis (NASH) and liver fibrosis. ...
Activation of innate immune systems including Toll-like receptor (TLR) signaling is a key in chronic liver disease. Recent stu …
Toll-Like Receptors: Ligands, Cell-Based Models, and Readouts for Receptor Action.
Dowling JK and Dellacasagrande J. Methods Mol Biol 2016. PMID 26803619
This chapter details Toll-like receptors (TLRs) and the tools available to study their biology in vitro. Key parameters to consider before exploring TLR action such as receptor localization, signaling pathways, nature of ligands and cellular expression are introduced. ...
This chapter details Toll-like receptors (TLRs) and the tools available to study their biology in vitro. Key parameters to con …
Sensing danger: toll-like receptors and outcome in allogeneic hematopoietic stem cell transplantation.
Kornblit B and Müller K. Bone Marrow Transplant 2017 - Review. PMID 27941769
Pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) play key roles in initiating innate and adaptive immune responses. ...
Pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) play key roles in initiating innate and adaptive immun …
Toll-like receptors and skin.
Ermertcan AT, et al. J Eur Acad Dermatol Venereol 2011 - Review. PMID 21492250
Toll-like receptors are important pattern recognition receptors which have key roles in both innate and adaptive immune responses. ...In this manuscript, the structure and functions of Toll-like receptors in immune responses, their impact on skin diseases and recent advances on therapeutic usage have been reviewed....
Toll-like receptors are important pattern recognition receptors which have key roles in both innate and adaptive immune respon
Toll-Like Receptors 2 and 4 Polymorphisms in Age-Related Macular Degeneration.
Güven M, et al. Curr Eye Res 2016. PMID 26398587
The purpose of this study was to determine whether common variation in the human toll-like receptors (TLRs) 2 and 4 alters the risk of AMD. ...
The purpose of this study was to determine whether common variation in the human toll-like receptors (TLRs) 2 and 4 alters the …
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