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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1966 4
1967 3
1968 2
1969 13
1970 7
1971 4
1972 4
1973 4
1974 11
1975 12
1976 14
1977 10
1978 11
1979 16
1980 21
1981 16
1982 13
1983 13
1984 14
1985 19
1986 27
1987 16
1988 20
1989 17
1990 25
1991 18
1992 21
1993 16
1994 13
1995 15
1996 17
1997 12
1998 11
1999 18
2000 11
2001 5
2002 18
2003 13
2004 18
2005 25
2006 26
2007 34
2008 30
2009 30
2010 34
2011 37
2012 35
2013 49
2014 36
2015 44
2016 28
2017 20
2018 28
2019 16
2020 0
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929 results
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Page 1
Cellular and molecular mechanisms of tooth root development.
Li J, et al. Development 2017 - Review. PMID 28143844 Free PMC article.
The tooth root is an integral, functionally important part of our dentition. The formation of a functional root depends on epithelial-mesenchymal interactions and integration of the root with the jaw bone, blood supply and nerve innervations. ...Here, we discuss recent advances in understanding the cellular and molecular mechanisms underlying tooth root formation. We review the function of cellular structure and components such as Hertwig's epithelial root sheath, cranial neural crest cells and stem cells residing in developing and adult teeth. ...
The tooth root is an integral, functionally important part of our dentition. The formation of a functional root depends …
[The role of bone morphogenetic protein signaling pathway in tooth root development].
Liu CW, et al. Hua Xi Kou Qiang Yi Xue Za Zhi 2018 - Review. PMID 30465352 Chinese. Free article.
BMP-mediated signaling plays an important role in tooth root development, which is a part of tooth development. Epithelial and mesenchymal interactions are involved in tooth root development, but the BMP signaling pathway has a different effect on tooth root development in epithelial and mesenchymal. This review summarizes the advances of BMP signaling in tooth root development....
BMP-mediated signaling plays an important role in tooth root development, which is a part of tooth development. Epithel …
Site-specific function and regulation of Osterix in tooth root formation.
He YD, et al. Int Endod J 2016 - Review. PMID 26599722 Free PMC article.
Congenital diseases of tooth roots, in terms of developmental abnormalities of short and thin root phenotypes, can lead to loss of teeth. A more complete understanding of the genetic molecular pathways and biological processes controlling tooth root formation is required. ...
Congenital diseases of tooth roots, in terms of developmental abnormalities of short and thin root phenotypes, can lead to los …
Osterix regulates tooth root formation in a site-specific manner.
Kim TH, et al. J Dent Res 2015. PMID 25568170 Free PMC article.
These phenotypes were closely related to the temporospatial expression pattern of Osx during tooth development. These findings indicate that Osx is required for root formation by regulating odontoblast differentiation, maturation, and root elongation. Cumulatively, our data strongly indicate that Osx is a site-specific regulator in tooth root formation....
These phenotypes were closely related to the temporospatial expression pattern of Osx during tooth development. These findings indica …
Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation.
Ono W, et al. Nat Commun 2016. PMID 27068606 Free PMC article.
Dental root formation is a dynamic process in which mesenchymal cells migrate toward the site of the future root, differentiate and secrete dentin and cementum. ...Deletion of histone deacetylase-4 (HDAC4) partially recapitulates the PPR deletion root phenotype. These findings indicate that PPR signalling in dental mesenchymal progenitors is essential for tooth root formation, underscoring importance of the PTHrP-PPR system during root morphogenesis and tooth eruption....
Dental root formation is a dynamic process in which mesenchymal cells migrate toward the site of the future root, differentiat …
Essential role of osterix for tooth root but not crown dentin formation.
Zhang H, et al. J Bone Miner Res 2015. PMID 25349111 Free PMC article.
Tooth is made of crown and root. It is widely believed that dentin formation in crown and root uses the same regulatory mechanism. ...Compared to the Nfic-KO tooth, which contains essentially no dentin tubules and remains in a "root-less" status at adult stages, the Osx-cKO root phenotype had partially improved at the late stage, indicating that other factors can compensate for OSX function. ...
Tooth is made of crown and root. It is widely believed that dentin formation in crown and root uses the same regulatory
Contribution of mesenchymal proliferation in tooth root morphogenesis.
Sohn WJ, et al. J Dent Res 2014. PMID 24155265 Free PMC article.
This study compared the morphogenesis and cellular events of the mesial-root-forming (MRF) and bifurcation-forming (BF) regions, located in the mesial and center of the first lower molar, to better define the developmental mechanisms involved in multi-rooted tooth formation. ...Both drugs resulted in altered morphological changes in the tooth root structures. In particular, the nocodazole- and cytochalasin-D-treated specimens showed a loss of root diameter and formation of a single-root, respectively. ...
This study compared the morphogenesis and cellular events of the mesial-root-forming (MRF) and bifurcation-forming (BF) regions, loca …
Revascularization: a treatment for permanent teeth with necrotic pulp and incomplete root development.
Wigler R, et al. J Endod 2013 - Review. PMID 23402501
There is a risk of inducing a dentin wall fracture or extending gutta-percha into the periapical tissue during compaction of the root canal filling. ...RESULTS: Disinfection of the root canal and stimulation of residual stem cells can induce formation of new hard tissue on the existing dentin wall and continued root development. ...
There is a risk of inducing a dentin wall fracture or extending gutta-percha into the periapical tissue during compaction of the root
Effects of mechanical force application on the developing root apex in rat maxillary molars.
Zhao L, et al. Arch Oral Biol 2019. PMID 30903951
Moreover, the force was released after 3 and 7 days of tooth movement, and root apical morphology at postnatal day 35 was subsequently observed. ...After 7 days of tooth movement, the root length decreased significantly with bending root apex, decreased cell proliferation and altered gene expression in developing root apex. ...
Moreover, the force was released after 3 and 7 days of tooth movement, and root apical morphology at postnatal day 35 was subs …
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