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Page 1
Evolutionary insights into toxins diversity in Ceriantharia (Cnidaria; Anthozoa).
Lopes CSS, Iwama RE, Cortez T, Andrade SCS, Klompen AML, Audino JA, Macrander J, Reitzel AM, Nagata RM, Lanna E, Martinez LD, Chagas BM, Stampar SN. Lopes CSS, et al. Toxicon X. 2025 Jun 4;27:100227. doi: 10.1016/j.toxcx.2025.100227. eCollection 2025 Sep. Toxicon X. 2025. PMID: 40552252 Free PMC article.
Pathophysiological role of endothelial biomarkers in Bothrops sp. venom-induced renal dysfunction and the therapeutic effect of antivenom.
Lopes NC, Meneses GC, Sales de Souza Santos R, Machado de Araújo L, Barroso Martins BV, Maria Dos Reis Araújo K, Nogueira de Aquino VH, Moreira de Almeida I, Brasileiro Mota SM, Bezerra da Silva Junior G, Rodrigues CE, De Francesco Daher E, Moura Moreira Albuquerque PL, Costa Martins AM. Lopes NC, et al. Toxicon X. 2025 May 20;26:100226. doi: 10.1016/j.toxcx.2025.100226. eCollection 2025 Jun. Toxicon X. 2025. PMID: 40525140 Free PMC article.
A polygeneric immunogen composed of 22 venoms from sub-Saharan African snakes to expand the neutralization scope of the EchiTAb-plus-ICP antivenom.
Sánchez A, Durán G, Cerdas M, Gutiérrez J, Segura Á, Herrera M, Vargas M, Sánchez A, Sánchez P, Solano G, Villalta M, Moscoso E, Umaña D, Arguedas M, Gómez A, Gutiérrez JM, León G. Sánchez A, et al. Toxicon X. 2024 Nov 16;24:100213. doi: 10.1016/j.toxcx.2024.100213. eCollection 2024 Dec. Toxicon X. 2024. PMID: 39640251 Free PMC article.
Supplementation of polyclonal antibodies, developed against epitope-string toxin-specific peptide immunogens, to commercial polyvalent antivenom, shows improved neutralization of Indian Big Four and Naja kaouthia snake venoms.
Chanda A, Salvi NC, Shelke PV, Kalita B, Patra A, Puzari U, Khadilkar MV, Mukherjee AK. Chanda A, et al. Toxicon X. 2024 Sep 26;24:100210. doi: 10.1016/j.toxcx.2024.100210. eCollection 2024 Dec. Toxicon X. 2024. PMID: 39398349 Free PMC article.
Bioprospection of rattlesnake venom peptide fractions with anti-adipose and anti-insulin resistance activity in vitro.
Meléndez-Martínez D, Ortega-Hernández E, Reza-Zaldívar EE, Carbajal-Saucedo A, Arnaud-Franco G, Gatica-Colima A, Plenge-Tellechea LF, Antunes-Ricardo M, Jacobo-Velázquez DA, Mayolo-Deloisa K, Lozano O, Rito-Palomares M, Benavides J. Meléndez-Martínez D, et al. Toxicon X. 2024 Sep 19;24:100209. doi: 10.1016/j.toxcx.2024.100209. eCollection 2024 Dec. Toxicon X. 2024. PMID: 39398348 Free PMC article.
Design, development and preclinical assessment of MENAVip-ICP, a new snake antivenom with potential coverage of species in the Middle East and North Africa regions.
Segura Á, Moscoso E, Umaña D, Vargas M, Sánchez A, Hernández A, Durán G, Villalta M, Gómez A, Herrera M, Arguedas M, Gutiérrez JM, León G. Segura Á, et al. Toxicon X. 2024 Aug 30;24:100206. doi: 10.1016/j.toxcx.2024.100206. eCollection 2024 Dec. Toxicon X. 2024. PMID: 39290878 Free PMC article.
Pilot-scale evaluation of a dynamic body-feed filtration system for primary clarification of snake antivenoms produced by the caprylic acid method.
Sánchez A, Cerdas M, Gutiérrez J, Vargas M, Segura Á, Herrera M, Chaves-Araya S, Sánchez R, Villalta M, Durán G, Sánchez A, Solano G, Cordero D, Sánchez P, Gutiérrez JM, León G. Sánchez A, et al. Toxicon X. 2024 Aug 13;23:100202. doi: 10.1016/j.toxcx.2024.100202. eCollection 2024 Sep. Toxicon X. 2024. PMID: 39246647 Free PMC article.
Clinical effects of immunization, bleeding, and albumin-based fluid therapy in horses used as immunoglobulin source to produce a polyspecific antivenom (Echitab-plus-ICP) towards venoms of African snakes.
Huertas RM, Arguedas M, Estrada JM, Moscoso E, Umaña D, Solano G, Vargas M, Segura Á, Sánchez A, Herrera M, Villalta M, Arroyo-Portilla C, Gutiérrez JM, León G. Huertas RM, et al. Toxicon X. 2023 Apr 17;18:100158. doi: 10.1016/j.toxcx.2023.100158. eCollection 2023 Jun. Toxicon X. 2023. PMID: 37180815 Free PMC article.
A subfraction obtained from the venom of the tarantula Poecilotheria regalis contains inhibitor cystine knot peptides and induces relaxation of rat aorta by inhibiting L-type voltage-gated calcium channels.
Díaz-Peña LF, Daniela TO, Aguilar MB, Luis E, Lazcano-Pérez F, Arreguín-Espinosa R, Hernandez-Cruz A, Ibarra-Alvarado C, García-Arredondo A. Díaz-Peña LF, et al. Toxicon X. 2023 Feb 17;18:100151. doi: 10.1016/j.toxcx.2023.100151. eCollection 2023 Jun. Toxicon X. 2023. PMID: 36873112 Free PMC article.
Histopathological, ultrastructural, and biochemical traits of apoptosis induced by peroxisomicine A1 (toxin T-514) from Karwinskia parvifolia in kidney and lung.
Soto-Domínguez A, Salas-Treviño D, Guillén-Meléndez GA, Castillo-Velázquez U, Ballesteros-Elizondo RG, Montes-de-Oca-Saucedo CR, Villa-Cedillo SA, Morales-Ávalos R, Rodríguez-Tovar LE, Montes-de-Oca-Luna R, Saucedo-Cárdenas O. Soto-Domínguez A, et al. Toxicon X. 2022 Dec 22;17:100148. doi: 10.1016/j.toxcx.2022.100148. eCollection 2023 Mar. Toxicon X. 2022. PMID: 36593898 Free PMC article.
Perspectives on snakebite envenoming care needs across different sociocultural contexts and health systems: A comparative qualitative analysis among US and Brazilian health providers.
Strand E, Murta F, Tupetz A, Barcenas L, Phillips AJ, Farias AS, Santos AC, Rocha GDS, Staton CA, Ramos FR, Machado VA, Wen FH, Vissoci JRN, Sachett J, Monteiro W, Gerardo CJ. Strand E, et al. Toxicon X. 2022 Dec 9;17:100143. doi: 10.1016/j.toxcx.2022.100143. eCollection 2023 Mar. Toxicon X. 2022. PMID: 36578905 Free PMC article.
Mapping of clinical management resources for snakebites and other animal envenomings in the Brazilian Amazon.
Beck TP, Tupetz A, Farias AS, Silva-Neto A, Rocha T, Smith ER, Murta F, Dourado FS, Cardoso D, Ramos TA, Sachett A, Pinto TS, Pucca MB, Sampaio V, Ramos F, Vissoci JN, Sachett J, Wen FH, Staton CA, Gerardo CJ, Monteiro W. Beck TP, et al. Toxicon X. 2022 Sep 16;16:100137. doi: 10.1016/j.toxcx.2022.100137. eCollection 2022 Dec. Toxicon X. 2022. PMID: 36160931 Free PMC article.
Corrigendum to "What is the impact of snakebite envenoming on domestic animals? A nation-wide community-based study in Nepal and Cameroon" [Toxicon: X 9 (2021) 100068].
Bolon I, Babo Martins S, Ochoa C, Alcoba G, Herrera M, Bofia Boyogueno HM, Sharma BK, Subedi M, Shah B, Wanda F, Sharma SK, Nkwescheu AS, Ray N, Chappuis F, Ruiz de Castañeda R. Bolon I, et al. Toxicon X. 2022 Jul 11;15:100133. doi: 10.1016/j.toxcx.2022.100133. eCollection 2022 Sep. Toxicon X. 2022. PMID: 35856052 Free PMC article.
Antifungal activity of Rhopalurus crassicauda venom against Candida spp.
Zottich U, de Oliveira IS, Fereira IG, Cerni FA, Karla de Castro Figueiredo B, Arantes EC, Gomes VM, Dias GB, Pucca MB. Zottich U, et al. Toxicon X. 2022 Mar 23;14:100120. doi: 10.1016/j.toxcx.2022.100120. eCollection 2022 Jun. Toxicon X. 2022. PMID: 35345480 Free PMC article.
In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus.
Menzies SK, Clare RH, Xie C, Westhorpe A, Hall SR, Edge RJ, Alsolaiss J, Crittenden E, Marriott AE, Harrison RA, Kool J, Casewell NR. Menzies SK, et al. Toxicon X. 2022 Mar 18;14:100118. doi: 10.1016/j.toxcx.2022.100118. eCollection 2022 Jun. Toxicon X. 2022. PMID: 35321116 Free PMC article.
Toxicon and Toxicon: X - 2022 and beyond.
Norton RS, Tambourgi DV. Norton RS, et al. Toxicon X. 2022 Feb 7;13:100098. doi: 10.1016/j.toxcx.2022.100098. eCollection 2022 Mar. Toxicon X. 2022. PMID: 35198966 Free PMC article. No abstract available.
Implications of bleaching on cnidarian venom ecology.
Kaposi KL, Courtney RL, Seymour JE. Kaposi KL, et al. Toxicon X. 2022 Jan 31;13:100094. doi: 10.1016/j.toxcx.2022.100094. eCollection 2022 Mar. Toxicon X. 2022. PMID: 35146416 Free PMC article. Review.
A transdisciplinary approach to snakebite envenoming.
Ruiz de Castañeda R, Bolon I, Gutiérrez JM. Ruiz de Castañeda R, et al. Toxicon X. 2021 Dec 22;13:100088. doi: 10.1016/j.toxcx.2021.100088. eCollection 2022 Mar. Toxicon X. 2021. PMID: 35005608 Free PMC article. No abstract available.
Access to antivenoms in the developing world: A multidisciplinary analysis.
Potet J, Beran D, Ray N, Alcoba G, Habib AG, Iliyasu G, Waldmann B, Ralph R, Faiz MA, Monteiro WM, de Almeida Gonçalves Sachett J, di Fabio JL, Cortés MLÁ, Brown NI, Williams DJ. Potet J, et al. Toxicon X. 2021 Oct 26;12:100086. doi: 10.1016/j.toxcx.2021.100086. eCollection 2021 Nov. Toxicon X. 2021. PMID: 34786555 Free PMC article.
Clinical management of snakebite envenoming: Future perspectives.
Hamza M, Knudsen C, Gnanathasan CA, Monteiro W, Lewin MR, Laustsen AH, Habib AG. Hamza M, et al. Toxicon X. 2021 Aug 8;11:100079. doi: 10.1016/j.toxcx.2021.100079. eCollection 2021 Sep. Toxicon X. 2021. PMID: 34430847 Free PMC article.
Chronic health effects and cost of snakebite.
Kasturiratne A, Lalloo DG, Janaka de Silva H. Kasturiratne A, et al. Toxicon X. 2021 Jul 17;9-10:100074. doi: 10.1016/j.toxcx.2021.100074. eCollection 2021 Jul. Toxicon X. 2021. PMID: 34355162 Free PMC article.
Citizen science and online data: Opportunities and challenges for snake ecology and action against snakebite.
Durso AM, Ruiz de Castañeda R, Montalcini C, Mondardini MR, Fernandez-Marques JL, Grey F, Müller MM, Uetz P, Marshall BM, Gray RJ, Smith CE, Becker D, Pingleton M, Louies J, Abegg AD, Akuboy J, Alcoba G, Daltry JC, Entiauspe-Neto OM, Freed P, de Freitas MA, Glaudas X, Huang S, Huang T, Kalki Y, Kojima Y, Laudisoit A, Limbu KP, Martínez-Fonseca JG, Mebert K, Rödel MO, Ruane S, Ruedi M, Schmitz A, Tatum SA, Tillack F, Visvanathan A, Wüster W, Bolon I. Durso AM, et al. Toxicon X. 2021 Jun 22;9-10:100071. doi: 10.1016/j.toxcx.2021.100071. eCollection 2021 Jul. Toxicon X. 2021. PMID: 34278294 Free PMC article.
The influence of ecological factors on cnidarian venoms.
O'Hara EP, Wilson D, Seymour JE. O'Hara EP, et al. Toxicon X. 2021 May 29;9-10:100067. doi: 10.1016/j.toxcx.2021.100067. eCollection 2021 Jul. Toxicon X. 2021. PMID: 34142080 Free PMC article. Review.
Isolation and structural characterization of bioactive compound from Aristolochia sprucei aqueous extract with anti-myotoxic activity.
González Rodríguez II, Francisco AF, Moreira-Dill LS, Quintero A, Guimarães CLS, Fernandes CAH, Takeda AAS, Zanchi FB, Caldeira CAS, Pereira PS, Fontes MRM, Zuliani JP, Soares AM. González Rodríguez II, et al. Toxicon X. 2020 Jun 20;7:100049. doi: 10.1016/j.toxcx.2020.100049. eCollection 2020 Sep. Toxicon X. 2020. PMID: 32613196 Free PMC article.
Bothrops atrox, the most important snake involved in human envenomings in the amazon: How venomics contributes to the knowledge of snake biology and clinical toxinology.
Monteiro WM, Contreras-Bernal JC, Bisneto PF, Sachett J, Mendonça da Silva I, Lacerda M, Guimarães da Costa A, Val F, Brasileiro L, Sartim MA, Silva-de-Oliveira S, Bernarde PS, Kaefer IL, Grazziotin FG, Wen FH, Moura-da-Silva AM. Monteiro WM, et al. Toxicon X. 2020 Apr 23;6:100037. doi: 10.1016/j.toxcx.2020.100037. eCollection 2020 Jun. Toxicon X. 2020. PMID: 32550592 Free PMC article.
Dagestan blunt-nosed viper, Macrovipera lebetina obtusa (Dwigubsky, 1832), venom. Venomics, antivenomics, and neutralization assays of the lethal and toxic venom activities by anti-Macrovipera lebetina turanica and anti-Vipera berus berus antivenoms.
Pla D, Quesada-Bernat S, Rodríguez Y, Sánchez A, Vargas M, Villalta M, Mesén S, Segura Á, Mustafin DO, Fomina YA, Al-Shekhadat RI, Calvete JJ. Pla D, et al. Toxicon X. 2020 Apr 20;6:100035. doi: 10.1016/j.toxcx.2020.100035. eCollection 2020 Jun. Toxicon X. 2020. PMID: 32550590 Free PMC article.
The comparative toxicity of Isocoma species in calves.
Davis TZ, Green BT, Stegelmeier BL, Lee ST. Davis TZ, et al. Toxicon X. 2020 Jan 2;5:100022. doi: 10.1016/j.toxcx.2019.100022. eCollection 2020 Mar. Toxicon X. 2020. PMID: 32550578 Free PMC article.
The emerging field of venom-microbiomics for exploring venom as a microenvironment, and the corresponding Initiative for Venom Associated Microbes and Parasites (iVAMP).
Ul-Hasan S, Rodríguez-Román E, Reitzel AM, Adams RMM, Herzig V, Nobile CJ, Saviola AJ, Trim SA, Stiers EE, Moschos SA, Keiser CN, Petras D, Moran Y, Colston TJ. Ul-Hasan S, et al. Toxicon X. 2019 Sep 20;4:100016. doi: 10.1016/j.toxcx.2019.100016. eCollection 2019 Oct. Toxicon X. 2019. PMID: 32550573 Free PMC article.