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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1994 68
1995 192
1996 270
1997 283
1998 302
1999 363
2000 379
2001 400
2002 401
2003 418
2004 396
2005 380
2006 398
2007 386
2008 406
2009 345
2010 377
2011 370
2012 361
2013 346
2014 281
2015 259
2016 262
2017 190
2018 180
2019 64
2020 4
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7,349 results
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Page 1
AP-1 Transcription Factor Serves as a Molecular Switch between Chlamydia pneumoniae Replication and Persistence.
Krämer S, et al. Infect Immun 2015. PMID 25895972 Free PMC article.
Here we focused on the interaction of chlamydiae with the host cell transcription factor activator protein 1 (AP-1) and its consequence on chlamydial development. ...In all, these data demonstrate that the AP-1 transcription factor is involved in C. pneumoniae development, with tanshinone IIA treatment resulting in persistence....
Here we focused on the interaction of chlamydiae with the host cell transcription factor activator protein 1 (AP
AP-1 Expression and its Clinical Relevance in Immune Disorders and Cancer.
Trop-Steinberg S and Azar Y. Am J Med Sci 2017 - Review. PMID 28502334
We review current knowledge regarding the functions of activator protein 1 (AP-1) as an important modulator in several immune disorders and carcinomas. ...AP-1 may enable the development of helpful markers to identify early-stage disease or to predict severity....
We review current knowledge regarding the functions of activator protein 1 (AP-1) as an important modulator in several …
Expression patterns of the activator protein-1 (AP-1) family members in lymphoid neoplasms.
Papoudou-Bai A, et al. Clin Exp Med 2017 - Review. PMID 27600282
The activator protein-1 (AP-1) is a dimeric transcription factor composed of proteins belonging to the Jun (c-Jun, JunB and JunD), Fos (c-Fos, FosB, Fra1 and Fra2) and activating transcription factor protein families. AP-1 is involved in various cellular events including differentiation, proliferation, survival and apoptosis. Deregulated expression of AP-1 transcription factors is implicated in the pathogenesis of various lymphomas such as classical Hodgkin lymphomas, anaplastic large cell lymphomas, diffuse large B cell lymphomas and adult T cell leukemia/lymphoma. ...
The activator protein-1 (AP-1) is a dimeric transcription factor composed of proteins belonging to the Ju …
Interactome analysis of transcriptional coactivator multiprotein bridging factor 1 unveils a yeast AP-1-like transcription factor involved in oxidation tolerance of mycopathogen Beauveria bassiana.
Chu XL, et al. Curr Genet 2018. PMID 28871395
As a transcriptional coactivator, multiprotein bridging factor 1 mediates the activity of transcription factor in diverse physiological processes, and its homolog in B. bassiana (BbMBF1) contributes to fungal oxidation tolerance. ...Importantly, a B. bassiana homolog of yeast AP-1-like transcription factor (BbAP-1) was specifically associated with the BbMBF1-interactome under oxidation and significantly contributed to fungal oxidation tolerance. ...
As a transcriptional coactivator, multiprotein bridging factor 1 mediates the activity of transcription facto
AP-1 Takes Centre Stage in Enhancer Chromatin Dynamics.
Madrigal P and Alasoo K. Trends Cell Biol 2018 - Review. PMID 29778529
Recent studies involving induced pluripotent stem cell (iPSC) reprogramming in mice and monocyte-to-macrophage differentiation in humans have revealed a role for the transcription factor (TF) activator protein 1 (AP-1) in chromatin accessibility. Enhancer selection may be determined not only by cell type-specific sets of TFs but also by broadly expressed ones like AP-1....
Recent studies involving induced pluripotent stem cell (iPSC) reprogramming in mice and monocyte-to-macrophage differentiation in humans hav …
Response to metals treatment of Fra1, a member of the AP-1 transcription factor family, in P. lividus sea urchin embryos.
Russo R, et al. Mar Environ Res 2018. PMID 29776592
To deeply address the response of Paracentrotus lividus embryos to these metals, we studied the expression profiling of Pl-Fra transcription factor (TF), relating it to Pl-jun, a potential partner for AP-1 complex formation, and to Pl-MT, known to be an AP-1 target and to have a protective role against heavy metals. The AP-1 TFs are found throughout the animal kingdom and are involved in many cellular events, i.e. cell proliferation and differentiation, immune and stress responses, cancer growth. ...
To deeply address the response of Paracentrotus lividus embryos to these metals, we studied the expression profiling of Pl-Fra transcript
Activator protein-1 (AP-1): a bridge between life and death in lung epithelial (A549) cells under hypoxia.
Yadav S, et al. Mol Cell Biochem 2017. PMID 28589371
Activator protein-1 (AP-1) transcription factor plays a central role in hypoxia to modulate the expression of genes that decides the fate of the cell. ...In conclusion, hypoxia for different time points activated different subunits of AP-1 that combined to form different heterodimers. ...
Activator protein-1 (AP-1) transcription factor plays a central role in hypoxia to modulate the expressio …
AP-1 as a regulator of cell life and death.
Shaulian E and Karin M. Nat Cell Biol 2002 - Review. PMID 11988758
The transcription factor AP-1 (activator protein-1) is involved in cellular proliferation, transformation and death. Using mice and cells lacking AP-1 components, the target-genes and molecular mechanisms mediating these processes were recently identified. ...
The transcription factor AP-1 (activator protein-1) is involved in cellular proliferation, transformation …
Regulation of AP-1 gene transcription factor binding activity in the rat brain during nicotine dependence.
Pandey SC, et al. Neurosci Lett 1999. PMID 10320004
The effects of acute and chronic nicotine treatment on activator protein-1 (AP-1) gene transcription factor binding activity in the rat cortex were investigated. AP-1 DNA binding activity was determined by the electrophoretic gel mobility shift assay. It was observed that 1 h after acute nicotine treatment (single injection) AP-1 DNA binding activity was significantly increased in the rat cortex. ...
The effects of acute and chronic nicotine treatment on activator protein-1 (AP-1) gene transcription factor
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.
Whitmarsh AJ and Davis RJ. J Mol Med (Berl) 1996 - Review. PMID 8912180
One nuclear target of these MAP kinase signaling pathways is the transcription factor AP-1. MAP kinases regulate AP-1 transcriptional activity by multiple mechanisms. Here we review recent progress towards understanding AP-1 regulation by the ERK, JNK, and p38 MAP kinase signal transduction pathways....
One nuclear target of these MAP kinase signaling pathways is the transcription factor AP-1. MAP kinases regulate …
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