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2014 23
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2016 40
2017 77
2018 106
2019 59
2020 0
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Management of delayed hemolytic transfusion reaction in sickle cell disease: Prevention, diagnosis, treatment.
Pirenne F, et al. Transfus Clin Biol 2017. PMID 28669521
Transfusion remains a key treatment of sickle cell disease complications. However, delayed hemolytic transfusion reaction, the most serious complication of transfusion, may be life-threatening if hyperhemolysis develops. ...Early diagnosis might make it possible to implement specific treatments in some cases, thereby avoiding the need for secondary transfusion. ...
Transfusion remains a key treatment of sickle cell disease complications. However, delayed hemolytic transfusion reaction
Transfusion-associated circulatory overload and transfusion-related acute lung injury.
Semple JW, et al. Blood 2019 - Review. PMID 30808638
Transfusion-associated circulatory overload (TACO) and transfusion-related acute lung injury (TRALI) are syndromes of acute respiratory distress that occur within 6 hours of blood transfusion. ...Collectively, this may result in improved diagnostics and development of therapeutic approaches for these life-threatening transfusion reactions....
Transfusion-associated circulatory overload (TACO) and transfusion-related acute lung injury (TRALI) are syndromes of acute re
Comparing transfusion reaction risks for various plasma products - an analysis of 7 years of ISTARE haemovigilance data.
Saadah NH, et al. Br J Haematol 2018. PMID 29318576
Plasma transfusions may result in transfusion reactions. We used the International Surveillance of Transfusion-Associated Reactions and Events (ISTARE) database, containing yearly reported national annual aggregate data on transfusion reactions from participating countries, to investigate risks of plasma transfusion reactions and compare transfusion reaction risks for different plasma types. We calculated risks for plasma transfusion reactions and compared transfusion reaction risks between plasma types using random effects regression on repeated measures. ...
Plasma transfusions may result in transfusion reactions. We used the International Surveillance of Transfusion-Associat …
Prevention of delayed hemolytic transfusion reaction.
Pirenne F. Transfus Clin Biol 2019 - Clinical Trial. PMID 30926306
Post-transfusion hemolysis is the most frequent immune reaction to transfusion in sickle cell disease. Its frequency is underestimated due to its biological and clinical characteristics. ...Prevention is based on the prevention of alloimmunization through the use of matched RBCs for highly immunogenic blood groups, taking into account the patient's transfusion history, particularly in patients undergoing occasional transfusion, which is associated with a higher risk of DHTR development than chronic transfusion. ...
Post-transfusion hemolysis is the most frequent immune reaction to transfusion in sickle cell disease. Its frequency is …
Perioperative bleeding management in pediatric patients
Goobie SM and Haas T. Curr Opin Anaesthesiol 2016 - Review. PMID 26844864 Free article.
Traditional bleeding management has consisted of transfusion of autologous blood products, however, there is strong evidence that transfusion-related side-effects are associated with increased morbidity and mortality in children. Especially concerning is the increased reported incidence of noninfectious adverse events such as transfusion-related acute lung injury, transfusion-related circulatory overload and transfusion-related immunomodulation. ...
Traditional bleeding management has consisted of transfusion of autologous blood products, however, there is strong evidence that …
An acute transfusion reaction.
Webb C, et al. Clin Med (Lond) 2018. PMID 29436447 Free PMC article.
We present the case of a 67-year-old man who suffered an acute anaphylactic reaction during red cell transfusion due to the presence of anti-IgA antibodies. ...This case highlights the need to consider the potential risks of blood component transfusion against the purported benefit....
We present the case of a 67-year-old man who suffered an acute anaphylactic reaction during red cell transfusion due to the pr …
The first case of severe acute hemolytic transfusion reaction caused by anti-Sc2.
Lemay AS, et al. Transfusion 2018. PMID 30299537
The transfusion history was reviewed and a monocyte monolayer assay (MMA) was performed. RESULTS: The patient was investigated for a RBC reaction 9 years prior, when she developed symptoms of HTR. ...Finally, the transfusion reaction reported herein occurred when she received by happenstance RBCs from the same donor who was associated with the remote reaction 9 years earlier. ...
The transfusion history was reviewed and a monocyte monolayer assay (MMA) was performed. RESULTS: The patient was investigated for a …
Transfusion-related red blood cell alloantibodies: induction and consequences.
Tormey CA and Hendrickson JE. Blood 2019 - Review. PMID 30808636 Free PMC article.
Blood transfusion is the most common procedure completed during a given hospitalization in the United States. Although often life-saving, transfusions are not risk-free. ...Alloantibodies may be clinically significant in future transfusion scenarios, potentially resulting in acute or delayed hemolytic transfusion reactions or in difficulty locating compatible RBC units for future transfusion. ...
Blood transfusion is the most common procedure completed during a given hospitalization in the United States. Although often life-sav …
Noninfectious transfusion-associated adverse events and their mitigation strategies.
Goel R, et al. Blood 2019 - Review. PMID 30808635
The most common noninfectious reactions include febrile nonhemolytic transfusion reactions, allergic transfusion reactions, transfusion-associated circulatory overload, transfusion-related acute lung injury, and acute and delayed hemolytic transfusion reactions. ...Hemovigilance systems for monitoring transfusion events have been developed and demonstrated decreases in some adverse events, such as hemolytic transfusion reactions. ...
The most common noninfectious reactions include febrile nonhemolytic transfusion reactions, allergic transfusion reactions, …
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