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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1963 1
1964 1
1969 2
1971 1
1973 1
1976 1
1977 1
1980 1
1981 1
1982 8
1983 3
1984 6
1985 1
1986 6
1987 5
1988 7
1989 11
1990 20
1991 21
1992 24
1993 27
1994 24
1995 28
1996 31
1997 35
1998 24
1999 32
2000 32
2001 34
2002 26
2003 32
2004 44
2005 57
2006 62
2007 59
2008 67
2009 73
2010 75
2011 74
2012 94
2013 115
2014 98
2015 117
2016 83
2017 71
2018 83
2019 75
2020 93
2021 71
2022 79
2023 73
2024 13

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1,810 results

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Page 1
Treponema denticola Has the Potential to Cause Neurodegeneration in the Midbrain via the Periodontal Route of Infection-Narrative Review.
Pisani F, Pisani V, Arcangeli F, Harding A, Singhrao SK. Pisani F, et al. Int J Environ Res Public Health. 2023 Jun 4;20(11):6049. doi: 10.3390/ijerph20116049. Int J Environ Res Public Health. 2023. PMID: 37297653 Free PMC article. Review.
On this basis, this review aims to discuss the hypothesis of the ability of Treponema denticola to damage the peripheral axons in the periodontal ligament, to evade the complemental pathway and microglial immune response, to determine the cytoskeletal impairment and …
On this basis, this review aims to discuss the hypothesis of the ability of Treponema denticola to damage the peripheral axons …
Potential Treponema denticola-based periodontal vaccine to resolve a global public health challenge: a narrative literature review.
Mirmohammadsadegh N, Mashreghi Mohammadi N, Amin M. Mirmohammadsadegh N, et al. Expert Rev Vaccines. 2022 May;21(5):621-632. doi: 10.1080/14760584.2022.2044798. Epub 2022 Mar 4. Expert Rev Vaccines. 2022. PMID: 35195497 Review.
AREAS COVERED: A comprehensive literature review was performed to summarize published studies in English during the period of 1990-2021 to discuss the rationales for developing periodontal vaccine, cost-effectiveness analyses on the prevention of periodontitis, Treponema
AREAS COVERED: A comprehensive literature review was performed to summarize published studies in English during the period of 1990-2021 to d …
Treponema denticola Induces Neuronal Apoptosis by Promoting Amyloid-beta Accumulation in Mice.
Wu L, Su X, Tang Z, Jian L, Zhu H, Cheng X, Wu H. Wu L, et al. Pathogens. 2022 Oct 5;11(10):1150. doi: 10.3390/pathogens11101150. Pathogens. 2022. PMID: 36297207 Free PMC article.
Periodontitis is a significant risk factor for AD. The periodontal pathogens Porphyromonas gingivalis and Treponema denticola have been shown to initiate the hallmark pathologies and behavioral symptoms of AD. ...
Periodontitis is a significant risk factor for AD. The periodontal pathogens Porphyromonas gingivalis and Treponema denticola
Treponema denticola Induces Alzheimer-Like Tau Hyperphosphorylation by Activating Hippocampal Neuroinflammation in Mice.
Tang Z, Cheng X, Su X, Wu L, Cai Q, Wu H. Tang Z, et al. J Dent Res. 2022 Jul;101(8):992-1001. doi: 10.1177/00220345221076772. Epub 2022 Feb 22. J Dent Res. 2022. PMID: 35193423
The periodontal pathogen Porphyromonas gingivalis and its virulence factors have been shown to initiate and promote the hallmark pathologies and behavioral symptoms of AD. A possible link between Treponema denticola, another main periodontal pathogen, and AD has bee …
The periodontal pathogen Porphyromonas gingivalis and its virulence factors have been shown to initiate and promote the hallmark pathologies …
Effect of Treponema Denticola Infection on Epithelial Cells.
Kokubu E, Kikuchi Y, Okamoto-Shibayama K, Ishihara K. Kokubu E, et al. Bull Tokyo Dent Coll. 2022 Mar 8;63(1):13-22. doi: 10.2209/tdcpublication.2021-0037. Epub 2022 Feb 15. Bull Tokyo Dent Coll. 2022. PMID: 35173086 Free article.
Chronic periodontitis is an infectious disease caused by periodontopathic bacteria in subgingival plaque. One major pathogen of this disease, Treponema denticola, has several virulence factors, including a major surface protein (Msp) and the surface protease dentili …
Chronic periodontitis is an infectious disease caused by periodontopathic bacteria in subgingival plaque. One major pathogen of this disease …
Treponema denticola as a prognostic biomarker for periodontitis in dogs.
Kwon D, Bae K, Kim H, Kim SH, Lee D, Lee JH. Kwon D, et al. PLoS One. 2022 Jan 21;17(1):e0262859. doi: 10.1371/journal.pone.0262859. eCollection 2022. PLoS One. 2022. PMID: 35061858 Free PMC article.
To investigate trends of periodontopathic bacteria in the samples of dogs, a quantitative real-time polymerase chain reaction (PCR) was performed for quantification of 11 human periodontopathic bacteria as follows: Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingiva …
To investigate trends of periodontopathic bacteria in the samples of dogs, a quantitative real-time polymerase chain reaction (PCR) was perf …
Periodontitis: a polymicrobial disruption of host homeostasis.
Darveau RP. Darveau RP. Nat Rev Microbiol. 2010 Jul;8(7):481-90. doi: 10.1038/nrmicro2337. Nat Rev Microbiol. 2010. PMID: 20514045 Review.
However, several bacterial species found in plaque (the 'red-complex' bacteria: Porphyromonas gingivalis, Tannerella forsythia and Treponema denticola) use various mechanisms to interfere with host defence mechanisms. ...
However, several bacterial species found in plaque (the 'red-complex' bacteria: Porphyromonas gingivalis, Tannerella forsythia and Trepon
The Treponema denticola DgcA protein (TDE0125) is a functional diguanylate cyclase.
Patel DT, O'Bier NS, Schuler EJA, Marconi RT. Patel DT, et al. Pathog Dis. 2021 Mar 20;79(3):ftab004. doi: 10.1093/femspd/ftab004. Pathog Dis. 2021. PMID: 33452878
Periodontal disease (PD) is a progressive inflammatory condition characterized by degradation of the gingival epithelium, periodontal ligament, and alveolar bone ultimately resulting in tooth loss. Treponema denticola is a keystone periopathogen that contributes to …
Periodontal disease (PD) is a progressive inflammatory condition characterized by degradation of the gingival epithelium, periodontal ligame …
Virulence factors of Treponema denticola.
Ishihara K. Ishihara K. Periodontol 2000. 2010 Oct;54(1):117-35. doi: 10.1111/j.1600-0757.2009.00345.x. Periodontol 2000. 2010. PMID: 20712637 Review. No abstract available.
Genetic Manipulations of Oral Spirochete Treponema denticola.
Kurniyati K, Li C. Kurniyati K, et al. Methods Mol Biol. 2021;2210:15-23. doi: 10.1007/978-1-0716-0939-2_2. Methods Mol Biol. 2021. PMID: 32815123 Free PMC article.
Among those cultivable species, due to its medical importance and genetic tractability, Treponema denticola, one of the keystone pathogens associated with human periodontitis, has emerged as a paradigm model organism to understanding the genetics, etiology, and path …
Among those cultivable species, due to its medical importance and genetic tractability, Treponema denticola, one of the keysto …
1,810 results