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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 2
1997 2
1998 106
1999 393
2000 415
2001 363
2002 340
2003 365
2004 383
2005 407
2006 360
2007 363
2008 371
2009 324
2010 350
2011 317
2012 315
2013 321
2014 300
2015 278
2016 240
2017 194
2018 228
2019 81
2020 3
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6,215 results
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The crosstalk between α-irradiated Beas-2B cells and its bystander U937 cells through MAPK and NF-κB signaling pathways.
Fu J, et al. Mutat Res 2016. PMID 26613333
In the present study, a cell co-culture system was used to investigate the interaction between α-particle irradiated human bronchial epithelial cells (Beas-2B) and its bystander macrophage U937 cells. ...For α-irradiated epithelial cells, the activation of NF-κB and MAPK pathways in U937 cells participated in detrimental cellular responses since the above inhibitors could largely attenuate cell viability loss and apoptosis of irradiated cells. ...
In the present study, a cell co-culture system was used to investigate the interaction between α-particle irradiated human bronchial epithel …
20(S)-Ginsenoside Rh2 Induce the Apoptosis and Autophagy in U937 and K562 Cells.
Zhuang J, et al. Nutrients 2018. PMID 29518056 Free PMC article.
By using the above methods, it was determined that apoptosis induced by 20(S)-GRh2 was more obvious in K562 than U937 cells and 20(S)-GRh2 could generate autophagy in K562 and U937 cells. When pretreated by a specific inhibitor of autophagy, (3-methyladenine), the 20(S)-GRh2-induced apoptosis was enhanced, which indicated that 20(S)-GRh2-induced autophagy may protect U937 and K562 cells from undergoing apoptotic cell death. ...
By using the above methods, it was determined that apoptosis induced by 20(S)-GRh2 was more obvious in K562 than U937 cells an …
Induction of Apoptosis in U937 Cells by Using a Combination of Bortezomib and Low-Intensity Ultrasound.
Saliev T, et al. Med Sci Monit 2016. PMID 28003640 Free PMC article.
Treated U937 cells were analyzed for viability and levels of early and late apoptosis. In addition, scanning electron microscopy analysis of treated cells was performed. ...The percentage of U937 cells in the late apoptosis stage was not significantly different from that in the group treated with bortezomib only. ...
Treated U937 cells were analyzed for viability and levels of early and late apoptosis. In addition, scanning electron microsco …
Cell Fractionation of U937 Cells in the Absence of High-speed Centrifugation.
McCaig WD, et al. J Vis Exp 2019. PMID 30735201
In this protocol we detail a method to obtain subcellular fractions of U937 cells without the use of ultracentrifugation or indiscriminate detergents. ...We have successfully used this method to separate cytosolic, plasma membrane and mitochondrial proteins in the human monocyte cell line U937....
In this protocol we detail a method to obtain subcellular fractions of U937 cells without the use of ultracentrifugation or in …
Hydroquinone-induced FOXP3-ADAM17-Lyn-Akt-p21 signaling axis promotes malignant progression of human leukemia U937 cells.
Chen YJ, et al. Arch Toxicol 2017. PMID 27307158
Proliferation and colony formation of U937/HQ cells were notably higher than those of U937 cells. Ten-eleven translocation methylcytosine dioxygenase-mediated demethylation of the Treg-specific demethylated region in FOXP3 gene resulted in higher FOXP3 expression in U937/HQ cells than in U937 cells. ...Moreover, U937/HQ cells showed higher Lyn-mediated Akt activation and cytoplasmic p21 expression than U937 cells did. Abolishment of Akt activation decreased cytoplasmic p21 expression in U937/HQ cells. ...
Proliferation and colony formation of U937/HQ cells were notably higher than those of U937 cells. Ten-eleven tra …
Macrophage-like U937 cells recognize collagen fibrils with strain-induced discrete plasticity damage.
Veres SP, et al. J Biomed Mater Res A 2015. PMID 24616426
In this study, we have demonstrated that U937 macrophage-like cells respond specifically to overload-damaged collagen fibrils. ...Matched-pairs were cultured with U937 cells differentiated to a macrophage-like form directly on the substrate. Morphological responses of the U937 cells to the two substrates-and evidence of collagenolysis by the cells-were assessed using scanning electron microscopy. ...
In this study, we have demonstrated that U937 macrophage-like cells respond specifically to overload-damaged collagen fibrils. …
Crosstalk Between Human Monocytic U937 Cells and Gingival Fibroblasts in Coculturally Enhanced Matrix Metalloproteinase-2 Expression.
Kuo PJ, et al. J Periodontol 2016. PMID 27294432
Synergistically enhanced MMP-2 expression in a coculture of human gingival fibroblasts (HGFs) and human monocytic U937 cells was observed. Crosstalk between these two cells via the extracellular matrix metalloproteinase inducer (EMMPRIN) was demonstrated. METHODS: Enzyme levels of MMP-2 in HGFs and direct coculture with U937 were examined by zymography. ...
Synergistically enhanced MMP-2 expression in a coculture of human gingival fibroblasts (HGFs) and human monocytic U937 cells w …
[Study of the effects and mechanism of all-trans retinoic acid on leukemic cell line U937 cells with NPM1 mutation].
Qiu SW, et al. Zhonghua Xue Ye Xue Za Zhi 2017. PMID 29166739 Chinese.
Objective: To investigate the effect and mechanism of all-trans retinoic acid (ATRA) on leukemic cell line U937 cells with NPM1 mutation. ...Besides, ATRA could synergize with drugs to suppress the leukemic cells survival more effectively when ATRA was administered after the cytotoxic drugs exposure in U937 leukemic cells with NPM1 mutation....
Objective: To investigate the effect and mechanism of all-trans retinoic acid (ATRA) on leukemic cell line U937 cells with NPM …
Monitoring of the interaction between U937 cells and electroactive daunomycin with an arginine-rich peptide.
Sugawara K, et al. Bioelectrochemistry 2015. PMID 26057596
Daunomycin penetrates the membrane of a U937 cell, which is a human histiocyte-related lymphoma cell. Several arginine-rich peptides have also exhibited a high degree of permeability with these cells. ...The peak current of daunomycin with U937 cells had decreased. For the mixture of the daunomycin/peptide-1 probe and cells, the electrode response was smaller than that of daunomycin with the cells. ...
Daunomycin penetrates the membrane of a U937 cell, which is a human histiocyte-related lymphoma cell. Several arginine-rich peptides …
[Proteomic analysis of U937 cells expressing Mycobacterium tuberculosis heat shock protein 16.3].
Li T, et al. Zhonghua Jie He He Hu Xi Za Zhi 2015. PMID 25791654 Chinese.
OBJECTIVE: To compare the protein expression differences between U937 macrophages expressing M. tuberculosis (MTB) Hsp16.3 protein and U937 macrophages expressing green fluorescent protein (GFP), and therefore to explore the protein expressions related to latent TB infection(LTBI). METHODS: U937 macrophages were infected with an integrase-deficient Lentivirus vector to transiently express MTB Hsp16.3, and green fluorescent protein (GFP) as a control. 2-DE was used to compare the differentially expressed proteins in the infected U937 cells. ...
OBJECTIVE: To compare the protein expression differences between U937 macrophages expressing M. tuberculosis (MTB) Hsp16.3 protein an …
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