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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 2
1953 2
1955 3
1959 2
1960 1
1961 1
1962 3
1963 1
1964 5
1965 5
1966 9
1967 10
1968 7
1969 6
1970 3
1971 7
1972 4
1973 4
1974 6
1975 19
1976 28
1977 26
1978 38
1979 40
1980 51
1981 70
1982 70
1983 179
1984 224
1985 345
1986 451
1987 507
1988 625
1989 748
1990 834
1991 878
1992 994
1993 1016
1994 1095
1995 1174
1996 1222
1997 1300
1998 1317
1999 1384
2000 1474
2001 1522
2002 1630
2003 1712
2004 1869
2005 2028
2006 2117
2007 2312
2008 2488
2009 2760
2010 3042
2011 3424
2012 3833
2013 4173
2014 4630
2015 4931
2016 5858
2017 6217
2018 6418
2019 6985
2020 7351
2021 7023
2022 5927
2023 5219
2024 2389

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101,785 results

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Page 1
制备人脐静脉内皮细胞和人肺腺癌细胞融合细胞的新方法.
席 玉. 席 玉. Technol Cancer Res Treat. 2021 Jan-Dec;20:15330338211034260. doi: 10.1177/15330338211034260. Technol Cancer Res Treat. 2021. PMID: 34318732 Free PMC article.
METHODS: A549 cells were induced by ethyl methane sulfonate (EMS) and 8-azaguanine (8-AG) to get hypoxanthine guanine phosphoribosyl transferase (HGPRT) auxotrophic A549 cells. ...VE-cadherin and platelet endothelial cell adhesion molecule-1 (CD31) wer …
METHODS: A549 cells were induced by ethyl methane sulfonate (EMS) and 8-azaguanine (8-AG) to get hypoxanthine guanine phosphor …
Baicalein increases cisplatin sensitivity of A549 lung adenocarcinoma cells via PI3K/Akt/NF-kappaB pathway.
Yu M, Qi B, Xiaoxiang W, Xu J, Liu X. Yu M, et al. Biomed Pharmacother. 2017 Jun;90:677-685. doi: 10.1016/j.biopha.2017.04.001. Epub 2017 Apr 14. Biomed Pharmacother. 2017. PMID: 28415048 Review.
Our study showed that baicalein significantly enhanced the chemosensitivity of cisplatin (CDDP) in vivo and in vitro. We found that A549/CDDP (resistant to CDDP) cells not only acquired epithelial-mesenchymal transition (EMT) phenotype, but also showed increased NF- …
Our study showed that baicalein significantly enhanced the chemosensitivity of cisplatin (CDDP) in vivo and in vitro. We found that A549
Identification and validation of ferroptosis-related genes in lipopolysaccharide-induced acute lung injury.
Wang S, Song Y, Xu F, Liu H, Shen Y, Hu L, Fu Y, Zhu L. Wang S, et al. Cell Signal. 2023 Aug;108:110698. doi: 10.1016/j.cellsig.2023.110698. Epub 2023 May 5. Cell Signal. 2023. PMID: 37149072
In vitro, the upregulated mRNA levels of CXCL2, IL-6, SLC2A1, FTH1, TNFAIP3, and downregulated NQO1 and CAV1 in LPS-stimulated BEAS-2B and A549 cells were verified. CONCLUSION: We identified 86 potential ferroptosis-related genes of LPS-induced ALI through RNA-seq. …
In vitro, the upregulated mRNA levels of CXCL2, IL-6, SLC2A1, FTH1, TNFAIP3, and downregulated NQO1 and CAV1 in LPS-stimulated BEAS-2B and …
Luteolin inhibits A549 cells proliferation and migration by down-regulating androgen receptors.
Li X, Tang Y, Liang P, Sun M, Li T, Shen Z, Sha S. Li X, et al. Eur J Med Res. 2023 Sep 16;28(1):353. doi: 10.1186/s40001-023-01302-4. Eur J Med Res. 2023. PMID: 37716981 Free PMC article.
METHODS: Molecular docking, network pharmacology methods and quantitative structure-activity relationship (QSAR) model were used to identify the active components of YQG and their possible mechanisms of action. Western blot analysis was used to measure AR expression in A549
METHODS: Molecular docking, network pharmacology methods and quantitative structure-activity relationship (QSAR) model were used to identify …
Anti-cancer activity of benzoxazinone derivatives via targeting c-Myc G-quadruplex structure.
Jiang S, Awadasseid A, Narva S, Cao S, Tanaka Y, Wu Y, Fu W, Zhao X, Wei C, Zhang W. Jiang S, et al. Life Sci. 2020 Oct 1;258:118252. doi: 10.1016/j.lfs.2020.118252. Epub 2020 Aug 10. Life Sci. 2020. PMID: 32791149
AIMS: This study aimed to analyze the impact of four synthesized benzoxazinone derivatives as screening drugs on c-Myc-overexpressed cancer cells (H7402, HeLa, SK-RC-42, SGC7901, and A549) and to explore their interaction mechanisms in detail. ...KEY F …
AIMS: This study aimed to analyze the impact of four synthesized benzoxazinone derivatives as screening drugs on c-Myc-overexp …
Regulation of Epithelial-Mesenchymal Transition of A549 Cells by Prostaglandin D(2).
Vafaeinik F, Kum HJ, Jin SY, Min DS, Song SH, Ha HK, Kim CD, Bae SS. Vafaeinik F, et al. Cell Physiol Biochem. 2022 Mar 25;56(2):89-104. doi: 10.33594/000000506. Cell Physiol Biochem. 2022. PMID: 35333485 Free article.
Stimulation of A549 cells with PGD(2) resulted in a significant reduction in proliferation, whereas invasion and migration were enhanced. The expression of E-cadherin was markedly downregulated, while Vimentin expression was upregulated after treatment of A549
Stimulation of A549 cells with PGD(2) resulted in a significant reduction in proliferation, whereas invasion and migration wer …
Anti-tumor alkaloids from Peganum harmala.
Zhang Q, Zan YH, Yang HG, Yang MY, Liu FS, Li SG, Peng XH, Lin B, Li ZL, Li DH, Hua HM. Zhang Q, et al. Phytochemistry. 2022 May;197:113107. doi: 10.1016/j.phytochem.2022.113107. Epub 2022 Feb 1. Phytochemistry. 2022. PMID: 35121215
The structures of the isolated compounds were determined based on their HR-ESI-MS data, extensive NMR spectroscopic analyses, and ECD calculations. 3-(4-Hydroxyphenyl)quinoline exhibited potent antiproliferative activity against the HepG-2 cell lines with an IC(50) value of 3.05 …
The structures of the isolated compounds were determined based on their HR-ESI-MS data, extensive NMR spectroscopic analyses, and ECD calcul …
Live-Cell-Templated Dynamic Combinatorial Chemistry.
Carbajo D, Pérez Y, Bujons J, Alfonso I. Carbajo D, et al. Angew Chem Int Ed Engl. 2020 Sep 21;59(39):17202-17206. doi: 10.1002/anie.202004745. Epub 2020 May 26. Angew Chem Int Ed Engl. 2020. PMID: 32348612
In order to do that, a chemical entity is used as template within a dynamic combinatorial library of interconverting species, so that the stronger binders are amplified due to the efficient interaction with the target. Here we employed whole A549 living cells as tem …
In order to do that, a chemical entity is used as template within a dynamic combinatorial library of interconverting species, so that the st …
Epithelial-to-mesenchymal transition proceeds through directional destabilization of multidimensional attractor.
Wang W, Poe D, Yang Y, Hyatt T, Xing J. Wang W, et al. Elife. 2022 Feb 21;11:e74866. doi: 10.7554/eLife.74866. Elife. 2022. PMID: 35188459 Free PMC article.
Through time-lapse imaging we recorded single cell trajectories of human A549/Vim-RFP cells undergoing EMT induced by different concentrations of exogenous TGF-beta in a multi-dimensional cell feature space. ...For instance, do all cells follow the same route …
Through time-lapse imaging we recorded single cell trajectories of human A549/Vim-RFP cells undergoing EMT induced by differen …
Bortezomib induces cellular senescence in A549 lung cancer cells by stimulating telomere shortening.
Wang L, Yin H, Huang S, Huang S, Huang C, Zhang Z, Liu H. Wang L, et al. Hum Exp Toxicol. 2022 Jan-Dec;41:9603271221124094. doi: 10.1177/09603271221124094. Hum Exp Toxicol. 2022. PMID: 36401358 Free article.
SA-beta-gal staining assay showed that BTZ caused a significant increase in beta-Gal positive A549 cells. BTZ also induced cell cycle arrest on G0/G1 phase in A549 cells. Furthermore, telomerase activity was markedly reduced in A549 cells
SA-beta-gal staining assay showed that BTZ caused a significant increase in beta-Gal positive A549 cells. BTZ also induced cel …
101,785 results
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