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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1963 3
1964 1
1965 27
1966 96
1967 178
1968 223
1969 225
1970 264
1971 299
1972 357
1973 363
1974 350
1975 339
1976 349
1977 325
1978 308
1979 295
1980 313
1981 304
1982 398
1983 422
1984 525
1985 567
1986 474
1987 430
1988 425
1989 534
1990 421
1991 505
1992 446
1993 457
1994 524
1995 415
1996 412
1997 379
1998 385
1999 321
2000 303
2001 287
2002 249
2003 260
2004 269
2005 231
2006 247
2007 245
2008 200
2009 189
2010 184
2011 194
2012 167
2013 144
2014 135
2015 94
2016 124
2017 117
2018 79
2019 26
2020 0
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16,081 results
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Page 1
Remodeling of the vascular tree in hypertension: drug effects.
Struyker Boudier HA, et al. Trends Pharmacol Sci 1990 - Review. PMID 2200183
The primary aim of current antihypertensive therapy is to lower blood pressure through the reduction of peripheral vascular resistance. Resistance reduction is achieved primarily by interference with acutely acting pressor stimuli. However, recent research has stressed the importance of slow pressor stimuli, which act by gradually remodeling the vascular tree. ...
The primary aim of current antihypertensive therapy is to lower blood pressure through the reduction of peripheral vascular resist
Acute effects of inhaled sulphur dioxide on pig nasal vascular and airway resistances.
Lung MA. Sheng Li Xue Bao 2014. PMID 24553872 Free article.
This study was to investigate the acute effects of SO2 on nasal vascular and airway resistances in anaesthetized pigs for elucidating the underlying vascular and control mechanisms. ...Nasal airway and lower airway pressures were measured to reflect airflow resistance changes. Systemic arterial pressure and nasal arterial flow were measured to calculate nasal vascular resistance. ...
This study was to investigate the acute effects of SO2 on nasal vascular and airway resistances in anaesthetized pigs for eluc …
Dose-related effects of pharmacological mediators on tracheal vascular resistance in dogs.
Laitinen LA, et al. Br J Pharmacol 1987. PMID 3427276 Free PMC article.
1 Various doses of mediators were tested on tracheal vascular resistance in dogs anaesthetized with pentobarbitone. Tracheal vascular resistance was determined by perfusing the cranial tracheal arteries at constant flows and measuring inflow pressures. 2 All drugs produced dose-related changes in vascular resistance. 3 The peptides bradykinin, substance P and vasoactive intestinal peptide (VIP) each had similar vasodilator potencies and were much more powerful than histamine, methacholine and salbutamol. 4 Platelet activating factor (Paf) was a weaker dilator than the peptides. Prostaglandins D2, E1 and F2 alpha had wide dilator potency ranges, PGE1 being very effective even at low concentrations. 5 Phenylephrine, an alpha-adrenoceptor agonist, was the only drug tested that always increased vascular resistance. 6 All the drugs studied also had effects on the contralateral tracheal vascular resistance....
1 Various doses of mediators were tested on tracheal vascular resistance in dogs anaesthetized with pentobarbitone. Tracheal …
Effects of propofol on mean arterial pressure and systemic vascular resistance during cardiopulmonary bypass.
Pensado A, et al. Acta Anaesthesiol Scand 1993 - Clinical Trial. PMID 8356864
This study was designed to evaluate the effects of propofol on mean arterial pressure (MAP) and systemic vascular resistance (SVR) during cardiopulmonary bypass (CPB). ...
This study was designed to evaluate the effects of propofol on mean arterial pressure (MAP) and systemic vascular resistanc
The total vascular burden, peripheral and coronary: vasodilator effects of nifedipine.
Opie LH and Commerford PJ. Am Heart J 1988 - Review. PMID 3276110
While the total ischemic burden on the left ventricle represents the combined effects of both symptomatic and asymptomatic myocardial ischemia, the total vascular burden has many components including an increased systemic peripheral vascular resistance, an increased pulmonary vascular resistance, and an increased coronary vascular resistance. ...In congestive heart failure, low-dose nifedipine reduces the afterload and has been shown to have beneficial effects in the majority of patients. ...
While the total ischemic burden on the left ventricle represents the combined effects of both symptomatic and asymptomatic myocardial …
Assessment of right ventricular responses to therapy in pulmonary hypertension
Spruijt OA, et al. Drug Discov Today 2014 - Review. PMID 24637045
Irrespective of its cause, pulmonary hypertension (PH) leads to an increase in pulmonary vascular resistance (PVR). Failing adaption of the right ventricle (RV) to the increased afterload is the main cause of death in PH patients and therefore monitoring RV function during treatment is essential. ...
Irrespective of its cause, pulmonary hypertension (PH) leads to an increase in pulmonary vascular resistance (PVR). Failing ad …
Systematic Review of Randomized Controlled Trials of Endothelin Receptor Antagonists for Pulmonary Arterial Hypertension
Kuntz M, et al. Lung 2016 - Review. PMID 27506903
Studies that analyzed 6-min walking distance, pulmonary vascular resistance, pulmonary arterial pressure, or WHO functional status were incorporated for analysis. ...RESULTS: A constant decrease in pulmonary vascular resistance and pulmonary arterial pressure was globally reported among the different studies, resulting in increased 6-min walking distance and functional status compared to placebo. ...
Studies that analyzed 6-min walking distance, pulmonary vascular resistance, pulmonary arterial pressure, or WHO functional st …
Effects of drug treatment on human resistance arteriole morphology in essential hypertension: direct evidence for structural remodelling of resistance vessels.
Heagerty AM, et al. Lancet 1988. PMID 2903951
To examine whether effective drug treatment would reverse the morphological changes in resistance arterioles which characterise untreated essential hypertension, the vessels' media thickness and contractility were measured before and after long-term treatment. ...Subcutaneous resistance arterioles were dissected and mounted in a myograph. Treatment did not affect the shift in sensitivity to noradrenaline in the presence of cocaine, sensitivity to exogenously administered calcium, and the rate of relaxation after withdrawal of vasoconstrictor stimuli. ...
To examine whether effective drug treatment would reverse the morphological changes in resistance arterioles which characteris …
[Venotonics]
Mikadze ISh. Vestn Khir Im I I Grek 2006 - Review. PMID 16752656 Russian.
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