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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 5
1997 9
1998 14
1999 17
2000 33
2001 28
2002 33
2003 33
2004 40
2005 29
2006 32
2007 41
2008 43
2009 28
2010 36
2011 35
2012 38
2013 24
2014 34
2015 18
2016 23
2017 14
2018 16
2019 10
2020 0
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575 results
Results by year
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Page 1
Multiple RPAs make WRN syndrome protein a superhelicase.
Lee M, Shin S, Uhm H, Hong H, Kirk J, Hyun K, Kulikowicz T, Kim J, Ahn B, Bohr VA, Hohng S. Lee M, et al. Nucleic Acids Res. 2018 May 18;46(9):4689-4698. doi: 10.1093/nar/gky272. Nucleic Acids Res. 2018. PMID: 29668972 Free PMC article.
Human RecQ helicases in DNA repair, recombination, and replication.
Croteau DL, Popuri V, Opresko PL, Bohr VA. Croteau DL, et al. Annu Rev Biochem. 2014;83:519-52. doi: 10.1146/annurev-biochem-060713-035428. Epub 2014 Mar 3. Annu Rev Biochem. 2014. PMID: 24606147 Free PMC article. Review.
WRN helicase is a synthetic lethal target in microsatellite unstable cancers.
Chan EM, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Bin Liu J, Lazaro JB, Gu P, Piett CG, Apffel A, Ali SO, Deasy R, Keskula P, Ng RWS, Roberts EA, Reznichenko E, Leung L, Alimova M, Schenone M, Islam M, Maruvka YE, Liu Y, Roper J, Raghavan S, Giannakis M, Tseng YY, Nagel ZD, D'Andrea A, Root DE, Boehm JS, Getz G, Chang S, Golub TR, Tsherniak A, Vazquez F, Bass AJ. Chan EM, et al. Nature. 2019 Apr;568(7753):551-556. doi: 10.1038/s41586-019-1102-x. Epub 2019 Apr 10. Nature. 2019. PMID: 30971823 Free PMC article.
G-quadruplexes and helicases.
Mendoza O, Bourdoncle A, Boulé JB, Brosh RM Jr, Mergny JL. Mendoza O, et al. Nucleic Acids Res. 2016 Mar 18;44(5):1989-2006. doi: 10.1093/nar/gkw079. Epub 2016 Feb 15. Nucleic Acids Res. 2016. PMID: 26883636 Free PMC article. Review.
Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.
Zhang W, Li J, Suzuki K, Qu J, Wang P, Zhou J, Liu X, Ren R, Xu X, Ocampo A, Yuan T, Yang J, Li Y, Shi L, Guan D, Pan H, Duan S, Ding Z, Li M, Yi F, Bai R, Wang Y, Chen C, Yang F, Li X, Wang Z, Aizawa E, Goebl A, Soligalla RD, Reddy P, Esteban CR, Tang F, Liu GH, Belmonte JC. Zhang W, et al. Science. 2015 Jun 5;348(6239):1160-3. doi: 10.1126/science.aaa1356. Epub 2015 Apr 30. Science. 2015. PMID: 25931448 Free PMC article.
Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer.
Shamanna RA, Lu H, Croteau DL, Arora A, Agarwal D, Ball G, Aleskandarany MA, Ellis IO, Pommier Y, Madhusudan S, Bohr VA. Shamanna RA, et al. Oncotarget. 2016 Mar 22;7(12):13269-84. doi: 10.18632/oncotarget.7906. Oncotarget. 2016. PMID: 26959889 Free PMC article.
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