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Year Number of Results
1969 1
1970 1
1977 1
1981 2
1983 1
1986 3
1987 38
1988 109
1989 132
1990 120
1991 133
1992 117
1993 110
1994 139
1995 147
1996 137
1997 166
1998 203
1999 193
2000 168
2001 181
2002 187
2003 202
2004 227
2005 246
2006 241
2007 273
2008 276
2009 212
2010 236
2011 225
2012 192
2013 159
2014 179
2015 176
2016 194
2017 177
2018 157
2019 145
2020 133
2021 131
2022 158
2023 198
2024 62

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5,950 results

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Page 1
Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy.
Waldhauer I, Gonzalez-Nicolini V, Freimoser-Grundschober A, Nayak TK, Fahrni L, Hosse RJ, Gerrits D, Geven EJW, Sam J, Lang S, Bommer E, Steinhart V, Husar E, Colombetti S, Van Puijenbroek E, Neubauer M, Cline JM, Garg PK, Dugan G, Cavallo F, Acuna G, Charo J, Teichgräber V, Evers S, Boerman OC, Bacac M, Moessner E, Umaña P, Klein C. Waldhauer I, et al. MAbs. 2021 Jan-Dec;13(1):1913791. doi: 10.1080/19420862.2021.1913791. MAbs. 2021. PMID: 33974508 Free PMC article.
The binding and immunostimulatory properties of FAP-IL2v were investigated in vitro and compared with FAP-IL2wt. Tumor targeting was investigated in tumor-bearing mice and in a rhesus monkey. The ability of FAP-IL2v to potentiate the efficacy of different imm …
The binding and immunostimulatory properties of FAP-IL2v were investigated in vitro and compared with FAP-IL2wt. Tumor targeting was investi …
Assessment of Blood Pressure in Irradiated Rhesus Macaques (Macaca mulatta).
Achilles S, Olson JD, Dugan GO, Mark Cline J. Achilles S, et al. Radiat Res. 2023 Jul 1;200(1):13-20. doi: 10.1667/RADE-22-00117.1. Radiat Res. 2023. PMID: 37083731
Because there is a link between high blood pressure and vascular disease in all these sites, we undertook a retrospective study to evaluate blood pressure and radiation in this cohort of animals. In this work, we utilized a cohort of nonhuman primates (rhesus
Because there is a link between high blood pressure and vascular disease in all these sites, we undertook a retrospective study to evaluate …
Multireceptor targeting of glioblastoma.
Sharma P, Sonawane P, Herpai D, D'Agostino R, Rossmeisl J, Tatter S, Debinski W. Sharma P, et al. Neurooncol Adv. 2020 Aug 26;2(1):vdaa107. doi: 10.1093/noajnl/vdaa107. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 33150335 Free PMC article.
We conjugated QUAD with a modified bacterial toxin PE38QQR and tested it in vitro and in vivo. RESULTS: The QUAD variants preserved functional characteristics of the respective ligands for the 4 receptors. The QUAD 3.0 variant conjugate was highly cytotoxic to GBM c …
We conjugated QUAD with a modified bacterial toxin PE38QQR and tested it in vitro and in vivo. RESULTS: The QUAD variants pres …
In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig.
Corona BT, Call JA, Borkowski M, Greising SM. Corona BT, et al. J Vis Exp. 2021 Sep 3;(175). doi: 10.3791/62905. J Vis Exp. 2021. PMID: 34542541
There are strengths and weaknesses to each of these preparations; however, a clear advantage of in vivo strength testing is the ability to perform repeated measurements in the same animal. Herein, the materials and methods to reliably assess isometric torque …
There are strengths and weaknesses to each of these preparations; however, a clear advantage of in vivo strength testing is th …
Self-Assembling Peptide Solution Accelerates Hemostasis.
Carter T, Qi G, Wang W, Nguyen A, Cheng N, Ju YM, Lee SJ, Yoo JJ, Atala A, Sun XS. Carter T, et al. Adv Wound Care (New Rochelle). 2021 Apr;10(4):191-203. doi: 10.1089/wound.2019.1109. Epub 2020 Sep 10. Adv Wound Care (New Rochelle). 2021. PMID: 32716728 Free PMC article.
In vivo hemostatic effects were studied using the Wistar rat model. ...Conclusion: This study demonstrates that h9e peptide is a promising hemostatic biomaterial, not only because of its greater hemostatic effect than commercial product Celox but also because
In vivo hemostatic effects were studied using the Wistar rat model. ...Conclusion: This study demonstrates that h9e pep
Oncogenic and tumor-suppressive mouse models for breast cancer engaging HER2/neu.
Fry EA, Taneja P, Inoue K. Fry EA, et al. Int J Cancer. 2017 Feb 1;140(3):495-503. doi: 10.1002/ijc.30399. Epub 2016 Sep 12. Int J Cancer. 2017. PMID: 27553713 Free PMC article. Review.
To understand the pathophysiology of HER2-driven carcinogenesis and test HER2-targeting therapeutic agents in vivo, numerous mouse models have been created that faithfully reproduce HER2(+) BCs in mice. They include MMTV-neu (active mutant or wild type …
To understand the pathophysiology of HER2-driven carcinogenesis and test HER2-targeting therapeutic agents in vivo, numerous …
Proceedings of the 2018 National Toxicology Program Satellite Symposium.
Elmore SA, Carreira V, Labriola CS, Mahapatra D, McKeag SR, Rinke M, Shackelford C, Singh B, Talley A, Wallace SM, Wancket LM, Willson CJ. Elmore SA, et al. Toxicol Pathol. 2018 Dec;46(8):865-897. doi: 10.1177/0192623318800734. Epub 2018 Oct 3. Toxicol Pathol. 2018. PMID: 30282530 Free PMC article.
Various lesions and other topics covered during the symposium included seminiferous tubule dysgenesis in rats, ameloblast and odontoblast degeneration/necrosis in a Sprague Dawley rat, intestinal leiomyositis in a beagle dog, gallbladder mucinous hyperplasia, …
Various lesions and other topics covered during the symposium included seminiferous tubule dysgenesis in rats, ameloblast and odontoblast de …
Estrogen/isoflavone interactions in cynomolgus macaques (Macaca fascicularis).
Cline JM, Wood CE. Cline JM, et al. Am J Primatol. 2009 Sep;71(9):722-31. doi: 10.1002/ajp.20680. Am J Primatol. 2009. PMID: 19322873 Review.
Soy isoflavones appear to decrease breast and endometrial cancer risk in human observational studies, but paradoxically stimulate growth of breast cancer cells in culture and uterine enlargement in rodents. We have shown that these compounds are not estrogenic in cynomolgus
Soy isoflavones appear to decrease breast and endometrial cancer risk in human observational studies, but paradoxically stimulate growth of …
Neuropsychology of cognitive aging in rhesus monkeys.
Baxter MG, Roberts MT, Roberts JA, Rapp PR. Baxter MG, et al. Neurobiol Aging. 2023 Oct;130:40-49. doi: 10.1016/j.neurobiolaging.2023.06.011. Epub 2023 Jun 21. Neurobiol Aging. 2023. PMID: 37453251 Free article.
Aged rhesus monkeys, like aged humans, show declines in cognitive function. We present cognitive test data from a large sample of male and female rhesus monkeys, 34 young (aged 3.5-13.6 years) and 71 aged (aged 19.9-32.5 years at the start of cognitive …
Aged rhesus monkeys, like aged humans, show declines in cognitive function. We present cognitive test data from a large sample …
Nonhuman primate models of social behavior and cocaine abuse.
Nader MA, Czoty PW, Nader SH, Morgan D. Nader MA, et al. Psychopharmacology (Berl). 2012 Nov;224(1):57-67. doi: 10.1007/s00213-012-2843-5. Epub 2012 Aug 16. Psychopharmacology (Berl). 2012. PMID: 22895674 Free PMC article. Review.
The following dependent variables are examined: (1) cocaine-induced changes in social behavior and (2) cocaine self-administration in cynomolgus monkeys of varying social ranks. The independent variables examined include several environmental and pharmacological man …
The following dependent variables are examined: (1) cocaine-induced changes in social behavior and (2) cocaine self-administration in cyn
5,950 results