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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1946 14
1947 12
1948 9
1949 12
1950 21
1951 20
1952 23
1953 31
1954 26
1955 28
1956 25
1957 45
1958 32
1959 23
1960 27
1961 32
1962 70
1963 112
1964 99
1965 56
1966 33
1967 33
1968 35
1969 45
1970 24
1971 37
1972 57
1973 45
1974 48
1975 35
1976 37
1977 35
1978 38
1979 41
1980 27
1981 47
1982 44
1983 33
1984 44
1985 47
1986 44
1987 56
1988 167
1989 404
1990 434
1991 467
1992 507
1993 539
1994 478
1995 619
1996 543
1997 601
1998 736
1999 744
2000 780
2001 891
2002 949
2003 1034
2004 1172
2005 1423
2006 1537
2007 1667
2008 1892
2009 2011
2010 2052
2011 2336
2012 2443
2013 2748
2014 2839
2015 2660
2016 2594
2017 2643
2018 2598
2019 1055
2020 17
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40,685 results
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Page 1
Definition and classification of cancer cachexia: an international consensus
Fearon K, et al. Lancet Oncol 2011 - Review. PMID 21296615
The agreed diagnostic criterion for cachexia was weight loss greater than 5%, or weight loss greater than 2% in individuals already showing depletion according to current bodyweight and height (body-mass index [BMI] <20 kg/m(2)) or skeletal muscle mass (sarcopenia). ...Severity can be classified according to degree of depletion of energy stores and body protein (BMI) in combination with degree of ongoing weight loss. ...
The agreed diagnostic criterion for cachexia was weight loss greater than 5%, or weight loss greater than 2% in …
Management of obesity
Bray GA, et al. Lancet 2016 - Review. PMID 26868660
A modern approach to obesity acknowledges the multifactorial determinants of weight gain and the health benefits to be derived from weight loss. ...For patients who struggle with weight loss and who would receive health benefit from weight loss, management of medications that are contributing to weight gain and use of approved medications for chronic weight management along with lifestyle changes are appropriate. ...
A modern approach to obesity acknowledges the multifactorial determinants of weight gain and the health benefits to be derived from …
Cancer Cachexia: Beyond Weight Loss.
Bruggeman AR, et al. J Oncol Pract 2016 - Review. PMID 27858548
The impact of cancer cachexia on quality of life, treatment-related toxicity, physical function, and mortality are well established; however, establishing a clinically meaningful definition has proven challenging because of the focus on weight loss alone. ...Oncologists must recognize cachexia beyond weight loss alone, focusing instead on body composition and physical functioning. ...
The impact of cancer cachexia on quality of life, treatment-related toxicity, physical function, and mortality are well established; however …
GLP-1 and weight loss: unraveling the diverse neural circuitry.
Kanoski SE, et al. Am J Physiol Regul Integr Comp Physiol 2016 - Review. PMID 27030669 Free PMC article.
Long-acting GLP-1 analogs potently reduce food intake and body weight, and recent discoveries reveal that peripheral administration of these drugs reduces food intake largely through humoral pathways involving direct action on brain GLP-1 receptors (GLP-1R). Thus, it is of critical importance to understand the neural systems through which GLP-1 and long-acting GLP-1 analogs reduce food intake and body weight. ...
Long-acting GLP-1 analogs potently reduce food intake and body weight, and recent discoveries reveal that peripheral administration o …
Nutrition support for treating cancer-associated weight loss: an update.
Molfino A, et al. Curr Opin Support Palliat Care 2018 - Review. PMID 30382948
PURPOSE OF REVIEW: Patients with cancer present high risk for involuntary body weight loss and reduced food intake, which, contributing to progressive tissue wasting and affecting the nutritional status, are often under-estimated in the clinical practice. In this article, we aimed at focusing on cancer-associated weight loss and investigating recent evidences on the indications of nutritional interventions to treat this condition. ...
PURPOSE OF REVIEW: Patients with cancer present high risk for involuntary body weight loss and reduced food intake, which, con …
Diagnostic criteria for the classification of cancer-associated weight loss.
Martin L, et al. J Clin Oncol 2015. PMID 25422490
PURPOSE: Existing definitions of clinically important weight loss (WL) in patients with cancer are unclear and heterogeneous and do not consider current trends toward obesity. ...Differences in survival were observed across five categories of BMI (< 20.0, 20.0 to 21.9, 22.0 to 24.9, 25.0 to 27.9, and ≥ 28.0 kg/m(2); P < .001) and five categories of %WL (-2.5% to -5.9%, -6.0% to -10.9%, -11.0% to -14.9%, ≥ -15.0%, and weight stable (± 2.4%); P < .001). ...
PURPOSE: Existing definitions of clinically important weight loss (WL) in patients with cancer are unclear and heterogeneous a …
Measuring cachexia-diagnostic criteria
Dev R. Ann Palliat Med 2019 - Review. PMID 30525765 Free article.
Weight loss in cancer patients is not readily reversible by conventional nutritional support. The definition of cachexia and sarcopenia are evolving with time, as well as the assessment of weight loss in cancer patients. ...For cancer patients with weight loss, assessments of BMI and percentage weight loss, symptoms which impact nutritional intake, quality of life, physical function, biological markers, energy expenditure, and body composition are ideally needed in order to measure cachexia and implement therapeutic interventions....
Weight loss in cancer patients is not readily reversible by conventional nutritional support. The definition of cachexia and s
The applicability of a weight loss grading system in cancer cachexia: a longitudinal analysis.
Vagnildhaug OM, et al. J Cachexia Sarcopenia Muscle 2017. PMID 28627024 Free PMC article.
For each patient, weight loss grade was scored 0-4. Weight loss grade 0 represents a high BMI with limited weight loss, progressing through to weight loss grade 4 representing low BMI and a high degree of weight loss. ...Median survival decreased across the weight loss grades ranging from 407 days (95% CI 312-502)-weight loss grade 0 to 119 days (95% CI 93-145)-weight loss grade 4. ...
For each patient, weight loss grade was scored 0-4. Weight loss grade 0 represents a high BMI with limited we
Prospective Evaluation of Internalized Weight Bias and Weight Change Among Successful Weight-Loss Maintainers.
Olson KL, et al. Obesity (Silver Spring) 2018. PMID 30421843 Free PMC article.
This study prospectively evaluated IWB as a predictor of weight change in a longitudinal observational study of successful weight-loss maintainers. ...A one-point reduction in WBIS-M score at follow-up was associated with a 3.0% weight loss. CONCLUSIONS: Among weight-loss maintainers, IWB may be a risk factor for weight gain among men. ...
This study prospectively evaluated IWB as a predictor of weight change in a longitudinal observational study of successful weight
Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice.
den Hartigh LJ, et al. PLoS One 2017. PMID 28245284 Free PMC article.
OBJECTIVE: We therefore sought to directly compare weight loss by 10,12 CLA versus caloric restriction (CR, 15-25%), an acceptable healthy method of weight loss, to determine how 10,12 CLA-mediated weight loss fails to improve glucose metabolism. ...Collectively, we have shown that weight loss due to 10,12 CLA supplementation or CR results in dramatically different metabolic phenotypes, with the latter promoting a healthier form of weight loss....
OBJECTIVE: We therefore sought to directly compare weight loss by 10,12 CLA versus caloric restriction (CR, 15-25%), an accept …
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