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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1956 1
1957 2
1958 1
1959 1
1960 1
1961 2
1962 2
1963 5
1964 8
1965 9
1966 8
1967 17
1968 25
1969 22
1970 27
1971 62
1972 45
1973 57
1974 46
1975 57
1976 77
1977 65
1978 49
1979 43
1980 33
1981 34
1982 36
1983 33
1984 47
1985 56
1986 26
1987 37
1988 22
1989 31
1990 25
1991 26
1992 24
1993 27
1994 24
1995 32
1996 38
1997 21
1998 41
1999 25
2000 44
2001 35
2002 52
2003 50
2004 47
2005 42
2006 51
2007 54
2008 59
2009 64
2010 61
2011 95
2012 91
2013 107
2014 75
2015 86
2016 76
2017 76
2018 62
2019 41
2020 4
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2,385 results
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Page 1
Xylitol Toxicosis in Dogs: An Update.
Murphy LA and Dunayer EK. Vet Clin North Am Small Anim Pract 2018 - Review. PMID 30064708
Xylitol ingestions in dogs may result in severe hypoglycemia followed by acute hepatic failure and associated coagulopathies. ...Because of increased availability of xylitol-containing products in the market and in the dog's environment, it is likely that there will continue to be increased exposures and toxicity in dogs....
Xylitol ingestions in dogs may result in severe hypoglycemia followed by acute hepatic failure and associated coagulopathies. ...Beca
Xylitol's Health Benefits beyond Dental Health: A Comprehensive Review.
Salli K, et al. Nutrients 2019 - Review. PMID 31390800 Free PMC article.
Xylitol has been widely documented to have dental health benefits, such as reducing the risk for dental caries. Here we report on other health benefits that have been investigated for xylitol. ...As a low caloric sweetener, xylitol may contribute to weight management. It has been suggested that xylitol also increases satiety, but these results are not convincing yet. ...
Xylitol has been widely documented to have dental health benefits, such as reducing the risk for dental caries. Here we report on oth
Effectiveness of Xylitol in Reducing Dental Caries in Children.
Marghalani AA, et al. Pediatr Dent 2017 - Review. PMID 28390459
PURPOSE: The purpose of this study was to evaluate the effectiveness of xylitol in reducing dental caries in children compared to no treatment, a placebo, or preventive strategies. ...CONCLUSIONS: The present systematic review examining the effectiveness of xylitol on caries incidence in children showed a small effect size in randomized controlled trials and a very low quality of evidence that makes preventive action of xylitol uncertain....
PURPOSE: The purpose of this study was to evaluate the effectiveness of xylitol in reducing dental caries in children compared to no …
Xylitol: a review on bioproduction, application, health benefits, and related safety issues.
Ur-Rehman S, et al. Crit Rev Food Sci Nutr 2015 - Review. PMID 24915309
Xylitol is a pentahydroxy sugar-alcohol which exists in a very low quantity in fruits and vegetables (plums, strawberries, cauliflower, and pumpkin). On commercial scale, xylitol can be produced by chemical and biotechnological processes. Chemical production is costly and extensive in purification steps. ...
Xylitol is a pentahydroxy sugar-alcohol which exists in a very low quantity in fruits and vegetables (plums, strawberries, cauliflowe
Effects of Consuming Xylitol on Gut Microbiota and Lipid Metabolism in Mice.
Uebanso T, et al. Nutrients 2017. PMID 28708089 Free PMC article.
However, the effects of lower daily doses of dietary xylitol on gut microbiota and lipid metabolism are unclear. We examined the effect of 40 and 200 mg/kg body weight/day xylitol intake on gut microbiota and lipid metabolism in mice. ...Relative to mice not fed xylitol, the addition of medium-dose xylitol to a regular and HFD in experimental mice reduced the abundance of fecal Bacteroidetes phylum and the genus Barnesiella, whereas the abundance of Firmicutes phylum and the genus Prevotella was increased in mice fed an HFD with medium-dose dietary xylitol. ...
However, the effects of lower daily doses of dietary xylitol on gut microbiota and lipid metabolism are unclear. We examined the effe …
Xylitol-containing products for preventing dental caries in children and adults.
Riley P, et al. Cochrane Database Syst Rev 2015 - Review. PMID 25809586
It has been postulated that the consumption of xylitol could help to prevent caries. The evidence on the effects of xylitol products is not clear and therefore it is important to summarise the available evidence to determine its effectiveness and safety. ...One study reported that xylitol syrup (8 g per day) reduced caries by 58% (95% CI 33% to 83%, 94 infants analysed, low quality evidence) when compared to a low-dose xylitol syrup (2.67 g per day) consumed for 1 year.The following results had 95% CIs that were compatible with both a reduction and an increase in caries associated with xylitol: xylitol lozenges versus no treatment in children (very low quality body of evidence); xylitol sucking tablets versus no treatment in infants (very low quality body of evidence); xylitol tablets versus control (sorbitol) tablets in infants (very low quality body of evidence); xylitol wipes versus control wipes in infants (low quality body of evidence).There was only one study investigating the effects of xylitol lozenges, when compared to control lozenges, in adults (low quality body of evidence). ...
It has been postulated that the consumption of xylitol could help to prevent caries. The evidence on the effects of xylitol pr …
Xylitol and its usage in ENT practice.
Sakallioğlu Ö, et al. J Laryngol Otol 2014 - Review. PMID 24999540
BACKGROUND: Xylitol is a five-carbon sugar alcohol. Natural sources of xylitol include plums, strawberries and raspberries. Xylitol is commercially available in chewing gums, lozenges, syrups, nasal sprays, toothpastes, mouthwashes and other products in some countries. ...RESULTS: Xylitol has no antibacterial properties of its own; rather, it appears to enhance the body's own innate immunity. Xylitol has anti-adhesive effects on micro-organisms like Streptococcus pneumoniae and Streptococcus mutans, inhibiting their growth. ...
BACKGROUND: Xylitol is a five-carbon sugar alcohol. Natural sources of xylitol include plums, strawberries and raspberries. …
Xylitol.
Peterson ME. Top Companion Anim Med 2013 - Review. PMID 23796483
Xylitol is a prevalent sugar substitute found in a wide variety of foods, particularly those labeled as "low carb." It is found in many medicines and dental products both for its antibacterial activity and to increase palatability. ...Xylitol is generally nontoxic to mammals except for dogs. In the dog, xylitol induces marked increases in insulin production and occasionally hepatopathy. ...
Xylitol is a prevalent sugar substitute found in a wide variety of foods, particularly those labeled as "low carb." It is found in ma
Xylitol Chewing Gums on the Market: Do They Prevent Caries?
Alanzi A, et al. Oral Health Prev Dent 2016. PMID 27175449
The mean measured xylitol content/piece was 0.33 ± 0.21 g. Xylitol content was < 0.3 g/ piece in 9 products, 0.3-0.5 g in 7 and > 0.5 g in 5 products. ...CONCLUSION: The majority of xylitol chewing gums sold on the GCC market do not provide the consumers with the recommended daily dose of xylitol for caries prevention. ...

The mean measured xylitol content/piece was 0.33 ± 0.21 g. Xylitol content was < 0.3 g/ piece in 9 products, 0.3-0.5 g in 7

Biosynthetic strategies to produce xylitol: an economical venture.
Xu Y, et al. Appl Microbiol Biotechnol 2019 - Review. PMID 31101942
Though great advances have been made in recent years for the biosynthesis of xylitol from xylose, glucose, and biomass hydrolysate, and the yield and productivity of xylitol are substantially improved by metabolic engineering and optimizing key metabolic pathway parameters, it is still far away from industrial-scale biosynthesis of xylitol. ...After a brief overview of chemical-based xylitol production, we critically analyzed and comprehensively summarized the major metabolic strategies used for the enhanced biosynthesis of xylitol in this review. ...
Though great advances have been made in recent years for the biosynthesis of xylitol from xylose, glucose, and biomass hydrolysate, a …
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