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Page 1
Acute Migraine Treatment in Adults.
Becker WJ. Becker WJ. Headache. 2015 Jun;55(6):778-93. doi: 10.1111/head.12550. Epub 2015 Apr 15. Headache. 2015. PMID: 25877672 Review.
Clinical features to be considered when choosing an acute migraine medication include usual headache intensity, usual rapidity of pain intensity increase, nausea, vomiting, degree of disability, patient response to previously used medications, history of headache recurrenc …
Clinical features to be considered when choosing an acute migraine medication include usual headache intensity, usual rapidity of pain …
Non-invasive neuromodulation in the acute treatment of migraine: a systematic review and meta-analysis of randomized controlled trials.
Clark O, Mahjoub A, Osman N, Surmava AM, Jan S, Lagman-Bartolome AM. Clark O, et al. Neurol Sci. 2022 Jan;43(1):153-165. doi: 10.1007/s10072-021-05664-7. Epub 2021 Oct 26. Neurol Sci. 2022. PMID: 34698941
We included randomized controlled clinical trials studying patients with migraine treated with any form of non-invasive neuromodulation. Primary outcome was pain freedom within 2 h post-treatment. Secondary outcomes were pain relief within 2-h post-treatment and sus …
We included randomized controlled clinical trials studying patients with migraine treated with any form of non-invasive neuromodulation. Pri …
Effect of Ubrogepant vs Placebo on Pain and the Most Bothersome Associated Symptom in the Acute Treatment of Migraine: The ACHIEVE II Randomized Clinical Trial.
Lipton RB, Dodick DW, Ailani J, Lu K, Finnegan M, Szegedi A, Trugman JM. Lipton RB, et al. JAMA. 2019 Nov 19;322(19):1887-1898. doi: 10.1001/jama.2019.16711. JAMA. 2019. PMID: 31742631 Free PMC article. Clinical Trial.
INTERVENTIONS: Ubrogepant 50 mg (n = 562), ubrogepant 25 mg (n = 561), or placebo (n = 563) for a migraine attack of moderate or severe pain intensity. MAIN OUTCOMES AND MEASURES: Co-primary efficacy outcomes were pain freedom and absence of the participant-designat …
INTERVENTIONS: Ubrogepant 50 mg (n = 562), ubrogepant 25 mg (n = 561), or placebo (n = 563) for a migraine attack of moderate or severe p …
Lasmiditan for the acute treatment of migraine.
DeJulio PA, Perese JK, Schuster NM, Oswald JC. DeJulio PA, et al. Pain Manag. 2021 Sep;11(5):437-449. doi: 10.2217/pmt-2021-0002. Epub 2021 Apr 12. Pain Manag. 2021. PMID: 33840206 Review.
Lay abstract Migraine is a leading cause of pain and disability worldwide. Triptans (e.g., sumatriptan) were the first migraine-specific drug class developed and have proven to be effective treatments. ...
Lay abstract Migraine is a leading cause of pain and disability worldwide. Triptans (e.g., sumatriptan) were the first migraine-speci …
Practice guidelines for the treatment of acute migraine and chronic knee osteoarthritis with paracetamol: an expert appraisal on evolution over time between scientific societies.
Perrot S, Eschalier A, Desmeules J, Lanteri-Minet M, Attal N. Perrot S, et al. Curr Med Res Opin. 2022 Sep;38(9):1579-1585. doi: 10.1080/03007995.2022.2076475. Epub 2022 May 31. Curr Med Res Opin. 2022. PMID: 35549792 Free article.
Despite evidence-based recommendations for management of acute and chronic pain with paracetamol, practices seem to vary considerably in its modalities of use, with or without restrictions, between renowned scientific societies and over time. ...Consensus is lacking …
Despite evidence-based recommendations for management of acute and chronic pain with paracetamol, practices seem to vary consi …
Rimegepant: acute treatment for migraine headaches.
Peters GL, Hennessey EK. Peters GL, et al. Pain Manag. 2021 May;11(3):259-266. doi: 10.2217/pmt-2020-0090. Epub 2021 Feb 8. Pain Manag. 2021. PMID: 33550872
Rimegepant is one of these newly approved agents for acute migraine treatment in adults with or without aura. Rimegepant has been found to decrease pain and symptoms associated with migraine attacks and is generally well-tolerated....
Rimegepant is one of these newly approved agents for acute migraine treatment in adults with or without aura. Rimegepant has been found to d …
Evaluation of Patients with Insufficient Efficacy and/or Tolerability to Triptans for the Acute Treatment of Migraine: A Systematic Literature Review.
Leroux E, Buchanan A, Lombard L, Loo LS, Bridge D, Rousseau B, Hopwood N, Matthews BR, Reuter U. Leroux E, et al. Adv Ther. 2020 Dec;37(12):4765-4796. doi: 10.1007/s12325-020-01494-9. Epub 2020 Sep 29. Adv Ther. 2020. PMID: 32990921 Free PMC article.
The most commonly applied measures of efficacy were headache pain freedom and pain relief at 2 h. Ten studies assessed efficacy of switching or optimizing treatment in patients with historical insufficient efficacy or tolerability to previous triptan treatment and d …
The most commonly applied measures of efficacy were headache pain freedom and pain relief at 2 h. Ten studies assessed efficac …
Practice guideline update summary: Acute treatment of migraine in children and adolescents: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society.
Oskoui M, Pringsheim T, Holler-Managan Y, Potrebic S, Billinghurst L, Gloss D, Hershey AD, Licking N, Sowell M, Victorio MC, Gersz EM, Leininger E, Zanitsch H, Yonker M, Mack K. Oskoui M, et al. Headache. 2019 Sep;59(8):1158-1173. doi: 10.1111/head.13628. Headache. 2019. PMID: 31529481
RESULTS: There is evidence to support the efficacy of the use of ibuprofen, acetaminophen (in children and adolescents), and triptans (mainly in adolescents) for the relief of migraine pain, although confidence in the evidence varies between agents. There is high confidenc …
RESULTS: There is evidence to support the efficacy of the use of ibuprofen, acetaminophen (in children and adolescents), and triptans (mainl …
Comparison of Remote Electrical Neuromodulation and Standard-Care Medications for Acute Treatment of Migraine in Adolescents: A Post Hoc Analysis.
Hershey AD, Irwin S, Rabany L, Gruper Y, Ironi A, Harris D, Sharon R, McVige J. Hershey AD, et al. Pain Med. 2022 Apr 8;23(4):815-820. doi: 10.1093/pm/pnab197. Pain Med. 2022. PMID: 34185084
Efficacy was compared within participants through the use of McNemar's test at four endpoints (2 hours after treatment): single-treatment pain freedom and pain relief, and consistency of pain freedom and pain relief (defined as response in at least 50% …
Efficacy was compared within participants through the use of McNemar's test at four endpoints (2 hours after treatment): single-treatment …
Combining Guided Intervention of Education and Relaxation (GIER) with Remote Electrical Neuromodulation (REN) in the Acute Treatment of Migraine.
Buse DC, Rabany L, Lin T, Ironi A, Connelly MA, Bickel JL. Buse DC, et al. Pain Med. 2022 Aug 31;23(9):1544-1549. doi: 10.1093/pm/pnac021. Pain Med. 2022. PMID: 35148414
The groups were compared on the proportion of migraine attacks in which they achieved pain relief, pain freedom, improvement of function, and return to normal function, all at 2 hours after treatment. ...CONCLUSIONS: The results suggest that combining the GIER behav …
The groups were compared on the proportion of migraine attacks in which they achieved pain relief, pain freedom, improvement o …
27 results