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Akkermansia muciniphila is a promising probiotic.
Zhang T, Li Q, Cheng L, Buch H, Zhang F. Zhang T, et al. Microb Biotechnol. 2019 Nov;12(6):1109-1125. doi: 10.1111/1751-7915.13410. Epub 2019 Apr 21. Microb Biotechnol. 2019. PMID: 31006995 Free PMC article. Review.
Akkermansia muciniphila (A. muciniphila), an intestinal symbiont colonizing in the mucosal layer, is considered to be a promising candidate as probiotics. ...Moreover, A. muciniphila may have a value in modifying cancer treatment. However, most of the …
Akkermansia muciniphila (A. muciniphila), an intestinal symbiont colonizing in the mucosal layer, is considered to be a …
Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms.
Cani PD, Depommier C, Derrien M, Everard A, de Vos WM. Cani PD, et al. Nat Rev Gastroenterol Hepatol. 2022 Oct;19(10):625-637. doi: 10.1038/s41575-022-00631-9. Epub 2022 May 31. Nat Rev Gastroenterol Hepatol. 2022. PMID: 35641786 Review.
Ever since Akkermansia muciniphila was discovered and characterized two decades ago, numerous studies have shown that the lack or decreased abundance of this commensal bacterium was linked with multiple diseases (such as obesity, diabetes, liver steatosis, inflammat …
Ever since Akkermansia muciniphila was discovered and characterized two decades ago, numerous studies have shown that the lack …
A next generation probiotic, Akkermansia muciniphila.
Zhai Q, Feng S, Arjan N, Chen W. Zhai Q, et al. Crit Rev Food Sci Nutr. 2019;59(19):3227-3236. doi: 10.1080/10408398.2018.1517725. Epub 2018 Oct 29. Crit Rev Food Sci Nutr. 2019. PMID: 30373382 Review.
Akkermansia muciniphila, a symbiotic bacterium of the mucus layer, can utilize mucin as its sole carbon, nitrogen, and energy source. As an abundant resident in the intestinal tract of humans and animals, the probiotic effects of A. muciniphila including meta …
Akkermansia muciniphila, a symbiotic bacterium of the mucus layer, can utilize mucin as its sole carbon, nitrogen, and energy …
The role of Akkermansia muciniphila in obesity, diabetes and atherosclerosis.
Hasani A, Ebrahimzadeh S, Hemmati F, Khabbaz A, Hasani A, Gholizadeh P. Hasani A, et al. J Med Microbiol. 2021 Oct;70(10). doi: 10.1099/jmm.0.001435. J Med Microbiol. 2021. PMID: 34623232 Review.
Alteration in the composition of the gut microbiota can lead to a number of chronic clinical diseases. Akkermansia muciniphila is an anaerobic bacteria constituting 3-5% of the gut microbial community in healthy adults. ...However, the underlying mechanisms by which …
Alteration in the composition of the gut microbiota can lead to a number of chronic clinical diseases. Akkermansia muciniphila …
Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer.
Derosa L, Routy B, Thomas AM, Iebba V, Zalcman G, Friard S, Mazieres J, Audigier-Valette C, Moro-Sibilot D, Goldwasser F, Silva CAC, Terrisse S, Bonvalet M, Scherpereel A, Pegliasco H, Richard C, Ghiringhelli F, Elkrief A, Desilets A, Blanc-Durand F, Cumbo F, Blanco A, Boidot R, Chevrier S, Daillère R, Kroemer G, Alla L, Pons N, Le Chatelier E, Galleron N, Roume H, Dubuisson A, Bouchard N, Messaoudene M, Drubay D, Deutsch E, Barlesi F, Planchard D, Segata N, Martinez S, Zitvogel L, Soria JC, Besse B. Derosa L, et al. Nat Med. 2022 Feb;28(2):315-324. doi: 10.1038/s41591-021-01655-5. Epub 2022 Feb 3. Nat Med. 2022. PMID: 35115705 Free PMC article.
In a previous retrospective analysis, we documented that fecal Akkermansia muciniphila (Akk) was associated with clinical benefit of ICI in patients with NSCLC or kidney cancer. ...
In a previous retrospective analysis, we documented that fecal Akkermansia muciniphila (Akk) was associated with clinical bene …
Akkermansia muciniphila Alleviates Dextran Sulfate Sodium (DSS)-Induced Acute Colitis by NLRP3 Activation.
Qu S, Fan L, Qi Y, Xu C, Hu Y, Chen S, Liu W, Liu W, Si J. Qu S, et al. Microbiol Spectr. 2021 Oct 31;9(2):e0073021. doi: 10.1128/Spectrum.00730-21. Epub 2021 Oct 6. Microbiol Spectr. 2021. PMID: 34612661 Free PMC article.
Akkermansia muciniphila has been proved to play a crucial role in the progression of colitis, but its underlying mechanism remains inconclusive. ...Mechanistically, the expression of NLRP3, caspase-1 p20, and IL-1beta p17 were upregulated in A. muciniphila-tr …
Akkermansia muciniphila has been proved to play a crucial role in the progression of colitis, but its underlying mechanism rem …
A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.
Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KC, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD. Plovier H, et al. Nat Med. 2017 Jan;23(1):107-113. doi: 10.1038/nm.4236. Epub 2016 Nov 28. Nat Med. 2017. PMID: 27892954 Free article. Clinical Trial.
Obesity and type 2 diabetes are associated with low-grade inflammation and specific changes in gut microbiota composition. We previously demonstrated that administration of Akkermansia muciniphila to mice prevents the development of obesity and associated complicati …
Obesity and type 2 diabetes are associated with low-grade inflammation and specific changes in gut microbiota composition. We previously dem …
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity.
Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, Guiot Y, Derrien M, Muccioli GG, Delzenne NM, de Vos WM, Cani PD. Everard A, et al. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9066-71. doi: 10.1073/pnas.1219451110. Epub 2013 May 13. Proc Natl Acad Sci U S A. 2013. PMID: 23671105 Free PMC article.
Microbial composition and the mechanisms of interaction with the host that affect gut barrier function during obesity and type 2 diabetes have not been elucidated. We recently isolated Akkermansia muciniphila, which is a mucin-degrading bacterium that resides in the …
Microbial composition and the mechanisms of interaction with the host that affect gut barrier function during obesity and type 2 diabetes ha …
Akkermansia muciniphila phospholipid induces homeostatic immune responses.
Bae M, Cassilly CD, Liu X, Park SM, Tusi BK, Chen X, Kwon J, Filipčík P, Bolze AS, Liu Z, Vlamakis H, Graham DB, Buhrlage SJ, Xavier RJ, Clardy J. Bae M, et al. Nature. 2022 Aug;608(7921):168-173. doi: 10.1038/s41586-022-04985-7. Epub 2022 Jul 27. Nature. 2022. PMID: 35896748 Free PMC article.
Multiple studies have established associations between human gut bacteria and host physiology, but determining the molecular mechanisms underlying these associations has been challenging(1-3). Akkermansia muciniphila has been robustly associated with positive system …
Multiple studies have established associations between human gut bacteria and host physiology, but determining the molecular mechanisms unde …
The human gut microbiota: Metabolism and perspective in obesity.
Gomes AC, Hoffmann C, Mota JF. Gomes AC, et al. Gut Microbes. 2018 Jul 4;9(4):308-325. doi: 10.1080/19490976.2018.1465157. Epub 2018 May 24. Gut Microbes. 2018. PMID: 29667480 Free PMC article. Review.
In obese people, this dysbiosis seems be related to increases of the phylum Firmicutes, the genus Clostridium, and the species Eubacterium rectale, Clostridium coccoides, Lactobacillus reuteri, Akkermansia muciniphila, Clostridium histolyticum, and Staphylococcus au …
In obese people, this dysbiosis seems be related to increases of the phylum Firmicutes, the genus Clostridium, and the species Eubacterium r …
1,063 results